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Regulation of immune reactivity by intercellular transferStimulating CD27 to quantitatively and qualitatively shape adaptive immunity to cancer.Acute Virus Control Mediated by Licensed NK Cells Sets Primary CD8+ T Cell Dependence on CD27 Costimulation.Effector CD4 T-cell transition to memory requires late cognate interactions that induce autocrine IL-2.Thymus-derived regulatory T cells restrain pro-inflammatory Th1 responses by downregulating CD70 on dendritic cells.T cells compete by cleaving cell surface CD27 and blocking access to CD70-bearing APCs.Tregs strip dendritic cells of CD70 to regulate Th1 differentiation.Trial Watch: Immunostimulatory monoclonal antibodies for oncological indications.
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description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 02 August 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
CD70 is downregulated by interaction with CD27.
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CD70 is downregulated by interaction with CD27.
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type
label
CD70 is downregulated by interaction with CD27.
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CD70 is downregulated by interaction with CD27.
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prefLabel
CD70 is downregulated by interaction with CD27.
@en
CD70 is downregulated by interaction with CD27.
@nl
P2860
P356
P1476
CD70 is downregulated by interaction with CD27
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Jonathan D Ashwell
Maria Letizia Giardino Torchia
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P304
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10.4049/JIMMUNOL.1300868
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P577
2013-08-02T00:00:00Z