Elimination of chronic viral infection by blocking CD27 signaling. - Wikidata - awgldk - TriplyDB

Elimination of chronic viral infection by blocking CD27 signaling.

Elimination of chronic viral infection by blocking CD27 signaling.

http://www.wikidata.org/entity/Q36228882

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Impact of Viral Infections on Hematopoiesis: From Beneficial to Detrimental Effects on Bone Marrow Output Acute Virus Control Mediated by Licensed NK Cells Sets Primary CD8+ T Cell Dependence on CD27 Costimulation."Negative vaccination" by specific CD4 T cell tolerisation enhances virus-specific protective antibody responses Polyclonal B cell differentiation and loss of gastrointestinal tract germinal centers in the earliest stages of HIV-1 infection Pretreatment levels of soluble cellular receptors and interleukin-6 are associated with HIV disease progression in subjects treated with highly active antiretroviral therapy.Destruction of lymphoid organ architecture and hepatitis caused by CD4+ T cells.OX40 facilitates control of a persistent virus infection.GITR intrinsically sustains early type 1 and late follicular helper CD4 T cell accumulation to control a chronic viral infection.Opposing effects of CD70 costimulation during acute and chronic lymphocytic choriomeningitis virus infection of mice Enhanced CD8 T cell responses through GITR-mediated costimulation resolve chronic viral infection.Expression of the immune regulation antigen CD70 in osteosarcoma.CD8+ T cell dysfunction and increase in murine gammaherpesvirus latent viral burden in the absence of 4-1BB ligand Thymus-derived regulatory T cells restrain pro-inflammatory Th1 responses by downregulating CD70 on dendritic cells.A subset of dendritic cells induces CD4+ T cells to produce IFN-gamma by an IL-12-independent but CD70-dependent mechanism in vivo.Translating insights from persistent LCMV infection into anti-HIV immunity.The role of IL-10 in regulating immunity to persistent viral infections Distinctive features of the differentiated phenotype and infiltration of tumor-reactive lymphocytes in clear cell renal cell carcinoma CD70 deficiency impairs effector CD8 T cell generation and viral clearance but is dispensable for the recall response to lymphocytic choriomeningitis virus.Cytotoxic T cells induce proliferation of chronic myeloid leukemia stem cells by secreting interferon-γ.Viral Persistence Induces Antibody Inflation without Altering Antibody Avidity Antibodies to the CD4-binding site of HIV-1 gp120 suppress gp120-specific CD4 T cell response while enhancing antibody response.CD4 T cell responses in latent and chronic viral infections.Costimulatory and Coinhibitory Receptor Pathways in Infectious Disease IL-10 and PD-L1 operate through distinct pathways to suppress T-cell activity during persistent viral infection.CD70 is downregulated by interaction with CD27.TNF superfamily: costimulation and clinical applications Role of CD27/CD70 pathway of activation in immunity and tolerance.The fourth dimension in immunological space: how the struggle for nutrients selects high-affinity lymphocytes.The contextual role of TNFR family members in CD8(+) T-cell control of viral infections.Regulation of hematopoietic and leukemic stem cells by the immune system.Therapeutic targeting of CD70 and CD27.CD70 and PD-L1 in anaplastic thyroid cancer - promising targets for immunotherapy.Irreversible splenic atrophy following chronic LCMV infection is associated with compromised immunity in mice.The price of the CD27-CD70 costimulatory axis: you can't have it all.Modulating CD27 signaling to treat cancer.CD27-CD70 costimulation controls T cell immunity during acute and persistent cytomegalovirus infection.CD27 costimulation contributes substantially to the expansion of functional memory CD8(+) T cells after peptide immunization.Altered distribution of natural killer cell subsets identified by CD56, CD27 and CD70 in primary and chronic human immunodeficiency virus-1 infection.T cell inhibitory mechanisms in a model of aggressive Non-Hodgkin's Lymphoma.CD70 encoded by modified vaccinia virus Ankara enhances CD8 T cell dependent protective immunity in MHC class II-deficient mice.

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P2860

Elimination of chronic viral infection by blocking CD27 signaling.

http://www.wikidata.org/entity/Q36228882

description

2006 nî lūn-bûn

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2006年の論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年论文

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2006年论文

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2006年论文

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name

Elimination of chronic viral infection by blocking CD27 signaling.

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Elimination of chronic viral infection by blocking CD27 signaling.

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type

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Elimination of chronic viral infection by blocking CD27 signaling.

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Elimination of chronic viral infection by blocking CD27 signaling.

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prefLabel

Elimination of chronic viral infection by blocking CD27 signaling.

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Elimination of chronic viral infection by blocking CD27 signaling.

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Journal of Experimental Medicine

P1476

Elimination of chronic viral infection by blocking CD27 signaling

@en

P2093

Adrian F Ochsenbein

http://www.w3.org/2001/XMLSchema#string

Bernhard Odermatt

http://www.w3.org/2001/XMLSchema#string

Hideo Yagita

http://www.w3.org/2001/XMLSchema#string

P2860

Mechanisms of hypergammaglobulinemia and impaired antigen-specific humoral immunity in HIV-1 infection

Marginal zone B cells

CD27, a member of the tumor necrosis factor receptor superfamily, activates NF-kappaB and stress-activated protein kinase/c-Jun N-terminal kinase via TRAF2, TRAF5, and NF-kappaB-inducing kinase

Human immunodeficiency virus genetic variation that can escape cytotoxic T cell recognition

Constitutive CD27/CD70 interaction induces expansion of effector-type T cells and results in IFNgamma-mediated B cell depletion

Characterization of tumor necrosis factor-deficient mice

Antibody neutralization and escape by HIV-1

HIV-1 evades antibody-mediated neutralization through conformational masking of receptor-binding sites

CD27-CD70 interactions regulate B-cell activation by T cells

CD27 is required for generation and long-term maintenance of T cell immunity.

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2145-2155

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9

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203

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Jean-Marc Nuoffer

Matthias S Matter

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2006-08-21T00:00:00Z

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6864046

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16923852

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2118404

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