Effect of the thymidylate synthase inhibitors on dUTP and TTP pool levels and the activities of DNA repair glycosylases on uracil and 5-fluorouracil in DNA.
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Checkpoint signaling, base excision repair, and PARP promote survival of colon cancer cells treated with 5-fluorodeoxyuridine but not 5-fluorouracil.SMUG1 but not UNG DNA glycosylase contributes to the cellular response to recovery from 5-fluorouracil induced replication stressSingle-strand selective monofunctional uracil-DNA glycosylase (SMUG1) deficiency is linked to aggressive breast cancer and predicts response to adjuvant therapy.UNG-initiated base excision repair is the major repair route for 5-fluorouracil in DNA, but 5-fluorouracil cytotoxicity depends mainly on RNA incorporation.Application of artificial neural network to investigate the effects of 5-fluorouracil on ribonucleotides and deoxyribonucleotides in HepG2 cells.Genomically Incorporated 5-Fluorouracil that Escapes UNG-Initiated Base Excision Repair Blocks DNA Replication and Activates Homologous RecombinationUracil DNA glycosylase initiates degradation of HIV-1 cDNA containing misincorporated dUTP and prevents viral integration.5-Fluorouracil mediated anti-cancer activity in colon cancer cells is through the induction of Adenomatous Polyposis Coli: Implication of the long-patch base excision repair pathway.Establishing a model for assessing DNA damage in murine brain cells as a molecular marker of chemotherapy-associated cognitive impairment.Diverse fates of uracilated HIV-1 DNA during infection of myeloid lineage cells.Uracil DNA glycosylase (UNG) loss enhances DNA double strand break formation in human cancer cells exposed to pemetrexedInhibition of uracil DNA glycosylase sensitizes cancer cells to 5-fluorodeoxyuridine through replication fork collapse-induced DNA damage.The curious chemical biology of cytosine: deamination, methylation, and oxidation as modulators of genomic potential.Personalizing colon cancer therapeutics: targeting old and new mechanisms of action.TAS-102, a novel antitumor agent: a review of the mechanism of action.Disordered N-Terminal Domain of Human Uracil DNA Glycosylase (hUNG2) Enhances DNA Translocation.Investigation of N-Terminal Phospho-Regulation of Uracil DNA Glycosylase Using Protein Semisynthesis.Trifluridine/tipiracil increases survival rates in peritoneal dissemination mouse models of human colorectal and gastric cancer.Glycogen Synthase Kinase 3 (GSK-3)-mediated Phosphorylation of Uracil N-Glycosylase 2 (UNG2) Facilitates the Repair of Floxuridine-induced DNA Lesions and Promotes Cell Survival.The applications of the novel polymeric fluoropyrimidine F10 in cancer treatment: current evidence.DNA synthesis as a therapeutic target: the first 65 years.AID/APOBEC deaminases disfavor modified cytosines implicated in DNA demethylation.Enzymatic excision of uracil residues in nucleosomes depends on the local DNA structure and dynamics.Synergistic Anticancer Activities of Natural Substances in Human Hepatocellular Carcinoma.5-Fluorouracil Treatment Alters the Efficiency of Translational Recoding.Measurement of nanoscale DNA translocation by uracil DNA glycosylase in human cells.
P2860
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P2860
Effect of the thymidylate synthase inhibitors on dUTP and TTP pool levels and the activities of DNA repair glycosylases on uracil and 5-fluorouracil in DNA.
description
2011 nî lūn-bûn
@nan
2011 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Effect of the thymidylate synt ...... cil and 5-fluorouracil in DNA.
@ast
Effect of the thymidylate synt ...... cil and 5-fluorouracil in DNA.
@en
Effect of the thymidylate synt ...... cil and 5-fluorouracil in DNA.
@nl
type
label
Effect of the thymidylate synt ...... cil and 5-fluorouracil in DNA.
@ast
Effect of the thymidylate synt ...... cil and 5-fluorouracil in DNA.
@en
Effect of the thymidylate synt ...... cil and 5-fluorouracil in DNA.
@nl
prefLabel
Effect of the thymidylate synt ...... cil and 5-fluorouracil in DNA.
@ast
Effect of the thymidylate synt ...... cil and 5-fluorouracil in DNA.
@en
Effect of the thymidylate synt ...... cil and 5-fluorouracil in DNA.
@nl
P2093
P2860
P356
P1433
P1476
Effect of the thymidylate synt ...... cil and 5-fluorouracil in DNA.
@en
P2093
Amy F Guminski
Breeana C Grogan
James T Stivers
Jared B Parker
P2860
P304
P356
10.1021/BI102046H
P407
P577
2011-01-11T00:00:00Z