Protection from lethal gram-negative bacterial sepsis by targeting Toll-like receptor 4. - Wikidata - awgldk - TriplyDB

Protection from lethal gram-negative bacterial sepsis by targeting Toll-like receptor 4.

Protection from lethal gram-negative bacterial sepsis by targeting Toll-like receptor 4.

http://www.wikidata.org/entity/Q37114768

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The Role of Toll-Like Receptor 4 in Infectious and Noninfectious Inflammation Balancing Innate Immunity and Inflammatory State via Modulation of Neutrophil Function: A Novel Strategy to Fight Sepsis Targeting toll-like receptors: promising therapeutic strategies for the management of sepsis-associated pathology and infectious diseases Chronic filarial infection provides protection against bacterial sepsis by functionally reprogramming macrophages Chitohexaose activates macrophages by alternate pathway through TLR4 and blocks endotoxemia Sepsis pathophysiology and anesthetic consideration Anti-inflammatory activity of a novel family of aryl ureas compounds in an endotoxin-induced airway epithelial cell injury model Animal models of sepsis and sepsis-induced kidney injury Toll-like receptor 4 expression on circulating leucocytes in hemolytic uremic syndrome.Toll-like receptor 4 decoy, TOY, attenuates gram-negative bacterial sepsis.The Toll-Like Receptor 4 Antagonist Eritoran Protects Mice from Lethal Filovirus Challenge.The glucocorticoid-induced leucine zipper (gilz/Tsc22d3-2) gene locus plays a crucial role in male fertility.CD14 inhibition efficiently attenuates early inflammatory and hemostatic responses in Escherichia coli sepsis in pigs.Common variants of TLR1 associate with organ dysfunction and sustained pro-inflammatory responses during sepsis.The Anticancer Peptide TAT-RasGAP317-326 Exerts Broad Antimicrobial Activity.Sirtuin 3 deficiency does not alter host defenses against bacterial and fungal infections.Characterization of protein tyrosine phosphatase H1 knockout mice in animal models of local and systemic inflammation Symbiotic bacterial metabolites regulate gastrointestinal barrier function via the xenobiotic sensor PXR and Toll-like receptor 4.Dominant role of the MyD88-dependent signaling pathway in mediating early endotoxin-induced murine ileus Bacterial flagellin elicits widespread innate immune defense mechanisms, apoptotic signaling, and a sepsis-like systemic inflammatory response in mice.Innate immunity and inflammation in sepsis: mechanisms of suppressed host resistance in mice treated with ethanol in a binge-drinking model Membrane TLR signaling mechanisms in the gastrointestinal tract during sepsis.Exhaustion of bacteria-specific CD4 T cells and microbial translocation in common variable immunodeficiency disorders.Renal effects of treatment with a TLR4 inhibitor in conscious septic sheep.Role of MyD88 and Toll-like receptors 2 and 4 in the sensing of Parachlamydia acanthamoebae.Endothelial dysfunction and renal fibrosis in endotoxemia-induced oliguric kidney injury: possible role of LPS-binding protein.Toll-like receptor 4 is essential to preserving cardiac function and survival in low-grade polymicrobial sepsis.Eritoran tetrasodium (E5564) treatment for sepsis: review of preclinical and clinical studies.Helminths and their implication in sepsis - a new branch of their immunomodulatory behaviour?Bone marrow and nonbone marrow Toll like receptor 4 regulate acute hepatic injury induced by endotoxemia.Current knowledge and future directions of TLR and NOD signaling in sepsis Characterization of sparstolonin B, a Chinese herb-derived compound, as a selective Toll-like receptor antagonist with potent anti-inflammatory properties.MyD88 and Trif signaling play distinct roles in cardiac dysfunction and mortality during endotoxin shock and polymicrobial sepsis.Fasciola hepatica fatty acid binding protein inhibits TLR4 activation and suppresses the inflammatory cytokines induced by lipopolysaccharide in vitro and in vivo.Estradiol and progesterone strongly inhibit the innate immune response of mononuclear cells in newborns.Enhancing Nrf2 pathway by disruption of Keap1 in myeloid leukocytes protects against sepsis Abdominal Distension and Escherichia coli Peritonitis in Mice Lacking Myeloid Differentiation Factor 88 Palmitoylation state impacts induction of innate and acquired immunity by the Salmonella enterica serovar typhimurium msbB mutant.Kallistatin treatment attenuates lethality and organ injury in mouse models of established sepsis Role of Toll interleukin-1 receptor (IL-1R) 8, a negative regulator of IL-1R/Toll-like receptor signaling, in resistance to acute Pseudomonas aeruginosa lung infection.

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Protection from lethal gram-negative bacterial sepsis by targeting Toll-like receptor 4.

http://www.wikidata.org/entity/Q37114768

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 30 January 2009

@en

vedecký článok

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vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

Protection from lethal gram-negative bacterial sepsis by targeting Toll-like receptor 4.

@en

Protection from lethal gram-negative bacterial sepsis by targeting Toll-like receptor 4.

@nl

type

label

Protection from lethal gram-negative bacterial sepsis by targeting Toll-like receptor 4.

@en

Protection from lethal gram-negative bacterial sepsis by targeting Toll-like receptor 4.

@nl

prefLabel

Protection from lethal gram-negative bacterial sepsis by targeting Toll-like receptor 4.

@en

Protection from lethal gram-negative bacterial sepsis by targeting Toll-like receptor 4.

@nl

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PNAS.0808146106

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Proceedings of the National Academy of Sciences of the United States of America

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Protection from lethal gram-negative bacterial sepsis by targeting Toll-like receptor 4.

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Anne-Laure Chanson

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Beat Michel Riederer

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Céline Froidevaux

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Davide Mauri

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Kim Burns

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Marlies Knaup Reymond

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P2860

MD-2, a molecule that confers lipopolysaccharide responsiveness on Toll-like receptor 4

Sepsis: rethinking the approach to clinical research

Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene

Crystal structure of the TLR4-MD-2 complex with bound endotoxin antagonist Eritoran

Structure and function of lipopolysaccharide binding protein

Crystal structures of human MD-2 and its complex with antiendotoxic lipid IVa

Pathogen recognition and innate immunity

Cutting edge: Toll-like receptor 4 (TLR4)-deficient mice are hyporesponsive to lipopolysaccharide: evidence for TLR4 as the Lps gene product

Recombinant bactericidal/permeability-increasing protein (rBPI21) as adjunctive treatment for children with severe meningococcal sepsis: a randomised trial. rBPI21 Meningococcal Sepsis Study Group

Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components

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2348-2352

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scholarly article

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10.1073/PNAS.0808146106

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7

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106

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Thierry Calandra

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2009-01-30T00:00:00Z

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23963774

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19181857

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Toll-like receptor

Gram-negative bacteria

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2650125

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