The role of nuclear factor kappaB in pancreatic cancer and the clinical applications of targeted therapy.
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Annexin 1 induced by anti-inflammatory drugs binds to NF-kappaB and inhibits its activation: anticancer effects in vitro and in vivoGlycogen synthase kinase-3 inhibition sensitizes pancreatic cancer cells to TRAIL-induced apoptosisQuantitative glycoproteomics analysis reveals changes in N-glycosylation level associated with pancreatic ductal adenocarcinoma.Genes-environment interactions in obesity- and diabetes-associated pancreatic cancer: a GWAS data analysis.Glycogen synthase kinase-3 inhibition disrupts nuclear factor-kappaB activity in pancreatic cancer, but fails to sensitize to gemcitabine chemotherapyDesign, synthesis, and biological evaluation of novel EF24 and EF31 analogs as potential IκB kinase β inhibitors for the treatment of pancreatic cancerα-Mangostin: a dietary antioxidant derived from the pericarp of Garcinia mangostana L. inhibits pancreatic tumor growth in xenograft mouse model.Pancreatic cancer and its stroma: a conspiracy theoryAberrant glycogen synthase kinase 3β is involved in pancreatic cancer cell invasion and resistance to therapy.Pharmacokinetics, protein binding and metabolism of a quinoxaline urea analog as an NF-κB inhibitor in mice and rats by LC-MS/MS.Discovering the route from inflammation to pancreatic cancer.Dimethylaminoparthenolide and gemcitabine: a survival study using a genetically engineered mouse model of pancreatic cancerMolecular characteristics of pancreatic ductal adenocarcinomaMoringa Oleifera aqueous leaf extract down-regulates nuclear factor-kappaB and increases cytotoxic effect of chemotherapy in pancreatic cancer cells.Curaxin CBL0137 eradicates drug resistant cancer stem cells and potentiates efficacy of gemcitabine in preclinical models of pancreatic cancer.Enhanced antitumor efficacy of gemcitabine by evodiamine on pancreatic cancer via regulating PI3K/Akt pathway.The activity of Gli transcription factors is essential for Kras-induced pancreatic tumorigenesis.Inhibition of the NF-κB signaling pathway by the curcumin analog, 3,5-Bis(2-pyridinylmethylidene)-4-piperidone (EF31): anti-inflammatory and anti-cancer properties.Stromal galectin-1 expression is associated with long-term survival in resectable pancreatic ductal adenocarcinomaExpression of NF-κB and PTEN in primary epithelial ovarian carcinoma and the correlation with chemoresistance.Aberrant glycogen synthase kinase 3β in the development of pancreatic cancer.Oncogenic transcription factors: cornerstones of inflammation-linked pancreatic carcinogenesisA dose-finding and pharmacodynamic study of bortezomib in combination with weekly paclitaxel in patients with advanced solid tumors.Targeting the NF-κB and mTOR pathways with a quinoxaline urea analog that inhibits IKKβ for pancreas cancer therapy.Apoptotic pathways in pancreatic ductal adenocarcinomaHoly Basil leaf extract decreases tumorigenicity and metastasis of aggressive human pancreatic cancer cells in vitro and in vivo: potential role in therapy.NF-kappaB signaling pathway and its therapeutic implications in human diseases.RETRACTED: 3,3'-Diindolylmethane enhances chemosensitivity of multiple chemotherapeutic agents in pancreatic cancer.Natural and synthetic α,β-unsaturated carbonyls for NF-κB inhibition.NF-κB signaling in prostate cancer: a promising therapeutic target?Fisetin, a natural flavonoid, targets chemoresistant human pancreatic cancer AsPC-1 cells through DR3-mediated inhibition of NF-kappaB.Effects of Raf kinase inhibitor protein expression on pancreatic cancer cell growth and motility: an in vivo and in vitro study.Flavonoid apigenin modified gene expression associated with inflammation and cancer and induced apoptosis in human pancreatic cancer cells through inhibition of GSK-3β/NF-κB signaling cascade.Dimethylamino parthenolide enhances the inhibitory effects of gemcitabine in human pancreatic cancer cells.The role of Rac1 in the regulation of NF-κB activity, cell proliferation, and cell migration in non-small cell lung carcinoma.Glycogen synthase kinase 3β inhibition sensitizes pancreatic cancer cells to gemcitabine.Escin Chemosensitizes Human Pancreatic Cancer Cells and Inhibits the Nuclear Factor-kappaB Signaling Pathway.Proteomic identification of potential prognostic biomarkers in resectable pancreatic ductal adenocarcinoma.Epicatechin-rich cocoa polyphenol inhibits Kras-activated pancreatic ductal carcinoma cell growth in vitro and in a mouse model.
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The role of nuclear factor kappaB in pancreatic cancer and the clinical applications of targeted therapy.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on April 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
The role of nuclear factor kap ...... lications of targeted therapy.
@en
The role of nuclear factor kap ...... lications of targeted therapy.
@nl
type
label
The role of nuclear factor kap ...... lications of targeted therapy.
@en
The role of nuclear factor kap ...... lications of targeted therapy.
@nl
prefLabel
The role of nuclear factor kap ...... lications of targeted therapy.
@en
The role of nuclear factor kap ...... lications of targeted therapy.
@nl
P1433
P1476
The role of nuclear factor kap ...... plications of targeted therapy
@en
P2093
Bryan Holcomb
C Max Schmidt
P304
P356
10.1097/MPA.0B013E31815B3207
P577
2008-04-01T00:00:00Z