Heterogeneity in protein expression induces metabolic variability in a modeled Escherichia coli population.
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A rheostat mechanism governs the bifurcation of carbon flux in mycobacteriaTowards a computational model of a methane producing archaeumReview of methods to probe single cell metabolism and bioenergetics.Emergence of robust growth laws from optimal regulation of ribosome synthesisSource and regulation of flux variability in Escherichia coli.Spatially-resolved metabolic cooperativity within dense bacterial colonies.Genetic variation in the nuclear and organellar genomes modulates stochastic variation in the metabolome, growth, and defense.Constrained Allocation Flux Balance AnalysisExploiting Bioprocessing Fluctuations to Elicit the Mechanistics of De Novo Lipogenesis in Yarrowia lipolytica.Origins of Cell-to-Cell Bioprocessing Diversity and Implications of the Extracellular Environment Revealed at the Single-Cell Level.Effects of DNA replication on mRNA noise.Whole Cell Modeling: From Single Cells to Colonies.Global characterization of in vivo enzyme catalytic rates and their correspondence to in vitro kcat measurementsHigh-throughput measurement of single-cell growth rates using serial microfluidic mass sensor arrays.Predictive sulfur metabolism - a field in flux.Parametric studies of metabolic cooperativity in Escherichia coli colonies: Strain and geometric confinement effects.Careful accounting of extrinsic noise in protein expression reveals correlations among its sources.From noise to synthetic nucleoli: can synthetic biology achieve new insights?Maximizing the stability of metabolic engineering-derived whole-cell biocatalysts.Growth resumption from stationary phase reveals memory in Escherichia coli culturesAn experimentally supported model of the Bacillus subtilis global transcriptional regulatory network.Cell-to-cell heterogeneity emerges as consequence of metabolic cooperation in a synthetic yeast community.Design of a bistable switch to control cellular uptake.An integrative, multi-scale, genome-wide model reveals the phenotypic landscape of Escherichia coli.Population FBA predicts metabolic phenotypes in yeast.Low variability of growth parameters among six O157:H7 and non-O157:H7 Escherichia coli strains.From Genes to Ecosystems in Microbiology: Modeling Approaches and the Importance of Individuality.Engineering Microbial Metabolite Dynamics and Heterogeneity.The impact of non-genetic heterogeneity on cancer cell death.The emergence of metabolic heterogeneity and diverse growth responses in isogenic bacterial cells.Exploiting nongenetic cell-to-cell variation for enhanced biosynthesis.Sources, propagation and consequences of stochasticity in cellular growth
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P2860
Heterogeneity in protein expression induces metabolic variability in a modeled Escherichia coli population.
description
article científic
@ca
article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on August 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Heterogeneity in protein expre ...... d Escherichia coli population.
@en
Heterogeneity in protein expre ...... d Escherichia coli population.
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type
label
Heterogeneity in protein expre ...... d Escherichia coli population.
@en
Heterogeneity in protein expre ...... d Escherichia coli population.
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prefLabel
Heterogeneity in protein expre ...... d Escherichia coli population.
@en
Heterogeneity in protein expre ...... d Escherichia coli population.
@nl
P2860
P50
P356
P1476
Heterogeneity in protein expre ...... ed Escherichia coli population
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P2093
Elijah Roberts
John Andrew Cole
P2860
P304
14006-14011
P356
10.1073/PNAS.1222569110
P407
P577
2013-08-01T00:00:00Z