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Analysis of gene expression profiles in HeLa cells in response to overexpression or siRNA-mediated depletion of NASPPhosphorylation of EZH2 activates STAT3 signaling via STAT3 methylation and promotes tumorigenicity of glioblastoma stem-like cellsSTAT3 protein up-regulates Gα-interacting vesicle-associated protein (GIV)/Girdin expression, and GIV enhances STAT3 activation in a positive feedback loop during wound healing and tumor invasion/metastasisSignal transducer and activator of transcription 3 regulation by novel binding partnersPivotal Importance of STAT3 in Protecting the Heart from Acute and Chronic Stress: New Advancement and Unresolved IssuesRegulation of STATs by polycystin-1 and their role in polycystic kidney diseaseProtein tyrosine phosphatases as wardens of STAT signalingThe consequences of selective inhibition of signal transducer and activator of transcription 3 (STAT3) tyrosine705 phosphorylation by phosphopeptide mimetic prodrugs targeting the Src homology 2 (SH2) domainObservation of unphosphorylated STAT3 core protein binding to target dsDNA by PEMSA and X-ray crystallographyhCAF1/CNOT7 regulates interferon signalling by targeting STAT1.The Signal Transducer and Activator of Transcription 1 (STAT1) Inhibits Mitochondrial Biogenesis in Liver and Fatty Acid Oxidation in Adipocytes.Nuclear EGFRvIII-STAT5b complex contributes to glioblastoma cell survival by direct activation of the Bcl-XL promoter.Interferon regulatory factor-8 is important for histone deacetylase inhibitor-mediated antitumor activity.STAT5 regulation of BCL10 parallels constitutive NFkappaB activation in lymphoid tumor cells.Protein tyrosine phosphatase 1B expression contributes to the development of breast cancer.Signal integration and gene induction by a functionally distinct STAT3 phosphoform.Co-activation of STAT3 and YES-Associated Protein 1 (YAP1) Pathway in EGFR-Mutant NSCLC.A phosphopeptide mimetic prodrug targeting the SH2 domain of Stat3 inhibits tumor growth and angiogenesis.Selective inhibition of the function of tyrosine-phosphorylated STAT3 with a phosphorylation site-specific intrabodyMurine gammaherpesvirus 68 has evolved gamma interferon and stat1-repressible promoters for the lytic switch gene 50.Interdependence of JAK-STAT and MAPK signaling pathways during EGF-mediated HTR-8/SVneo cell invasion.Regulation and function of signal transducer and activator of transcription 3.PE‑induced apoptosis in SMMC‑7721 cells: involvement of Erk and Stat signalling pathways.Studies on mechanisms of interferon-gamma action in pancreatic cancer using a data-driven and model-based approach.A STAT3-decoy oligonucleotide induces cell death in a human colorectal carcinoma cell line by blocking nuclear transfer of STAT3 and STAT3-bound NF-κB.Human cytomegalovirus IE1 protein elicits a type II interferon-like host cell response that depends on activated STAT1 but not interferon-γRole of EZH2 in cancer stem cells: from biological insight to a therapeutic target.The cleaved cytoplasmic tail of polycystin-1 regulates Src-dependent STAT3 activation.Stat3 directly controls the expression of Tbx5, Nkx2.5, and GATA4 and is essential for cardiomyocyte differentiation of P19CL6 cells.Thymidine phosphorylase inhibits vascular smooth muscle cell proliferation via upregulation of STAT3STAT3 is constitutively phosphorylated on serine 727 residues, binds DNA, and activates transcription in CLL cells.A novel mechanism of skin tumor promotion involving interferon-gamma (IFNγ)/signal transducer and activator of transcription-1 (Stat1) signaling.Drug-repositioning screening identified piperlongumine as a direct STAT3 inhibitor with potent activity against breast cancer.Involvement of Stat3 in mouse brain development and sexual dimorphism: a proteomics approach.Unphosphorylated STAT5A stabilizes heterochromatin and suppresses tumor growth.Alternative ways of modulating JAK-STAT pathway: Looking beyond phosphorylation.A signal transducer and activator of transcription 3·Nuclear Factor κB (Stat3·NFκB) complex is necessary for the expression of fascin in metastatic breast cancer cells in response to interleukin (IL)-6 and tumor necrosis factor (TNF)-αSTAT-3 activates NF-kappaB in chronic lymphocytic leukemia cells.Signal transducer and activator of transcription 3 activation up-regulates interleukin-6 autocrine production: a biochemical and genetic study of established cancer cell lines and clinical isolated human cancer cells.Viability and stress protection of chronic lymphoid leukemia cells involves overactivation of mitochondrial phosphoSTAT3Ser727.
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on April 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Roles of unphosphorylated STATs in signaling.
@en
Roles of unphosphorylated STATs in signaling.
@nl
type
label
Roles of unphosphorylated STATs in signaling.
@en
Roles of unphosphorylated STATs in signaling.
@nl
prefLabel
Roles of unphosphorylated STATs in signaling.
@en
Roles of unphosphorylated STATs in signaling.
@nl
P2860
P356
P1433
P1476
Roles of unphosphorylated STATs in signaling.
@en
P2093
George R Stark
Jinbo Yang
P2860
P2888
P304
P356
10.1038/CR.2008.41
P577
2008-04-01T00:00:00Z