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Leishmania metacyclogenesis is promoted in the absence of purinesThe Crystal Structure and Activity of a Putative Trypanosomal Nucleoside Phosphorylase Reveal It to be a Homodimeric Uridine PhosphorylaseThe Leishmania donovani UMP Synthase Is Essential for Promastigote Viability and Has an Unusual Tetrameric Structure That Exhibits Substrate-controlled OligomerizationThe crystal structure of Leishmania major N5,N10-methylenetetrahydrofolate dehydrogenase/cyclohydrolase and assessment of a potential drug targetCrystal structures of isoorotate decarboxylases reveal a novel catalytic mechanism of 5-carboxyl-uracil decarboxylation and shed light on the search for DNA decarboxylaseInduction of a stringent metabolic response in intracellular stages of Leishmania mexicana leads to increased dependence on mitochondrial metabolismA Multiplatform Metabolomic Approach to the Basis of Antimonial Action and Resistance in Leishmania infantumImmucillins Impair Leishmania (L.) infantum chagasi and Leishmania (L.) amazonensis Multiplication In VitroImmunoinformatics Features Linked to Leishmania Vaccine Development: Data Integration of Experimental and In Silico Studies.Leishmania induces survival, proliferation and elevated cellular dNTP levels in human monocytes promoting acceleration of HIV co-infection.Adaptive responses to purine starvation in Leishmania donovani.Purine restriction induces pronounced translational upregulation of the NT1 adenosine/pyrimidine nucleoside transporter in Leishmania major.Metabolic reprogramming during purine stress in the protozoan pathogen Leishmania donovaniIsotopomer profiling of Leishmania mexicana promastigotes reveals important roles for succinate fermentation and aspartate uptake in tricarboxylic acid cycle (TCA) anaplerosis, glutamate synthesis, and growth.Comprehensive proteomics analysis of glycosomes from Leishmania donovaniPurine salvage in Leishmania: complex or simple by design?Purine salvage pathways in the intraerythrocytic malaria parasite Plasmodium falciparum.Methylene tetrahydrofolate dehydrogenase/cyclohydrolase and the synthesis of 10-CHO-THF are essential in Leishmania major.The enzymes of the 10-formyl-tetrahydrofolate synthetic pathway are found exclusively in the cytosol of the trypanosomatid parasite Leishmania major.An ab Initio structural model of a nucleoside permease predicts functionally important residues.The purinosome, a multi-protein complex involved in the de novo biosynthesis of purines in humans.Transporters for drug delivery and as drug targets in parasitic protozoa.The Transcriptome of Leishmania major Developmental Stages in Their Natural Sand Fly VectorGenomic organization of leishmania species.Antiviral screening identifies adenosine analogs targeting the endogenous dsRNA Leishmania RNA virus 1 (LRV1) pathogenicity factor.Crithidia fasciculata adenosine transporter 1 (CfAT1), a novel high-affinity equilibrative nucleoside transporter specific for adenosine.Molecular cloning, expression and enzymatic assay of pteridine reductase 1 from Iranian lizard Leishmania.Metabolism
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on January 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Purine and pyrimidine metabolism in Leishmania.
@en
Purine and pyrimidine metabolism in Leishmania.
@nl
type
label
Purine and pyrimidine metabolism in Leishmania.
@en
Purine and pyrimidine metabolism in Leishmania.
@nl
prefLabel
Purine and pyrimidine metabolism in Leishmania.
@en
Purine and pyrimidine metabolism in Leishmania.
@nl
P2093
P1476
Purine and pyrimidine metabolism in Leishmania.
@en
P2093
Buddy Ullman
Cassandra S Arendt
Jan M Boitz
Nicola S Carter
Phillip Yates
P304
P356
10.1007/978-0-387-77570-8_12
P407
P577
2008-01-01T00:00:00Z