Clonal evolution of a follicular lymphoma: evidence for antigen selection.
about
Chronic active B-cell-receptor signalling in diffuse large B-cell lymphomaOngoing immunoglobulin somatic mutation in germinal center B cell-like but not in activated B cell-like diffuse large cell lymphomasTargeting the B-cell receptor signaling pathway in B lymphoid malignanciesMolecular definition of the germinal centre stage of B-cell differentiation.In situ analysis of the variable heavy chain gene of an IgM/IgG-expressing follicular lymphoma: evidence for interfollicular trafficking of tumor cells.Immunoglobulin VH gene mutational analysis suggests that primary effusion lymphomas derive from different stages of B cell maturation.Clonal expansion in follicular lymphoma occurs subsequent to antigenic selection.Genetics of follicular lymphoma transformation.Antibody V(h) repertoire differences between resolving and chronically evolving hepatitis C virus infections.B-cell signaling networks reveal a negative prognostic human lymphoma cell subset that emerges during tumor progressionSomatic hypermutation and B-cell lymphoma.The biology of human lymphoid malignancies revealed by gene expression profiling.T(11;18)(q21;q21)-positive gastrointestinal MALT lymphomas are heterogeneous with respect to the V(H) gene mutation status.Frequent occurrence of highly expanded but unrelated B-cell clones in patients with multiple myeloma.Apoptosis in lymphocytic leukemias and lymphomas.Malignant B cells and antigenic receptor: necessity or habit?Splenic marginal zone lymphomas appear to originate from different B cell typesMechanisms of B-cell lymphoma pathogenesis.Chronic hepatitis C virus infection breaks tolerance and drives polyclonal expansion of autoreactive B cells.Passenger transgenes reveal intrinsic specificity of the antibody hypermutation mechanism: clustering, polarity, and specific hot spots.Clonal evolution of B cells in transformation from low- to high-grade lymphoma.Molecular characterization of IgA- and/or IgG-switched chronic lymphocytic leukemia B cellsPathogenesis of follicular lymphomaSomatic diversification and selection of immunoglobulin heavy and light chain variable region genes in IgG+ CD5+ chronic lymphocytic leukemia B cells.Hodgkin and Reed-Sternberg cells in Hodgkin's disease represent the outgrowth of a dominant tumor clone derived from (crippled) germinal center B cells.Evidence for selective transformation of autoreactive immature plasma cells in mice deficient in FaslSelf-antigen recognition by follicular lymphoma B-cell receptors.Next generation sequencing of the clonal IGH rearrangement detects ongoing mutations and interfollicular trafficking in in situ follicular neoplasia.Somatic mutation of the 5' noncoding region of the BCL-6 gene is associated with intraclonal diversity and clonal selection in histological transformation of follicular lymphomaHodgkin and Reed-Sternberg cells in lymphocyte predominant Hodgkin disease represent clonal populations of germinal center-derived tumor B cells.Effect of Helicobacter pylori eradication on ongoing mutation of immunoglobulin genes in gastric MALT lymphomaNonstereotyped lymphoma B cell receptors recognize vimentin as a shared autoantigenCD70 as a therapeutic target in human malignancies.Follicular lymphoma of the thyroid gland.A molecular analysis of biclonal follicular lymphoma: further evidence for bone marrow origin and clonal selection.Minimal residual disease detection in lymphoma and multiple myeloma: impact on therapeutic paradigms.Clinical implications and prognostic role of minimal residual disease detection in follicular lymphomaCatalog of genetic progression of human cancers: non-Hodgkin lymphoma.Immunoglobulin gene sequence analysis to further assess B-cell origin of multiple myeloma.Apparent bypass of negative selection in CD8+ tumours in CD2-myc transgenic mice.
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P2860
Clonal evolution of a follicular lymphoma: evidence for antigen selection.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on August 1992
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Clonal evolution of a follicular lymphoma: evidence for antigen selection.
@en
Clonal evolution of a follicular lymphoma: evidence for antigen selection.
@nl
type
label
Clonal evolution of a follicular lymphoma: evidence for antigen selection.
@en
Clonal evolution of a follicular lymphoma: evidence for antigen selection.
@nl
prefLabel
Clonal evolution of a follicular lymphoma: evidence for antigen selection.
@en
Clonal evolution of a follicular lymphoma: evidence for antigen selection.
@nl
P2860
P356
P1476
Clonal evolution of a follicular lymphoma: evidence for antigen selection.
@en
P2093
P2860
P304
P356
10.1073/PNAS.89.15.6770
P407
P577
1992-08-01T00:00:00Z