An intact sialoadhesin (Sn/SIGLEC1/CD169) is not required for attachment/internalization of the porcine reproductive and respiratory syndrome virus
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Use of the CRISPR/Cas9 system to produce genetically engineered pigs from in vitro-derived oocytes and embryosAntigenic and Biological Characterization of ORF2-6 Variants at Early Times Following PRRSV InfectionThe interplay between Siglecs and sialylated pathogensPrecision engineering for PRRSV resistance in pigs: Macrophages from genome edited pigs lacking CD163 SRCR5 domain are fully resistant to both PRRSV genotypes while maintaining biological function.N-glycosylation profiling of porcine reproductive and respiratory syndrome virus envelope glycoprotein 5A single amino acid deletion in the matrix protein of porcine reproductive and respiratory syndrome virus confers resistance to a polyclonal swine antibody with broadly neutralizing activity.Transcriptome Analysis of Pig In Vivo, In Vitro-Fertilized, and Nuclear Transfer Blastocyst-Stage Embryos Treated with Histone Deacetylase Inhibitors Postfusion and Activation Reveals Changes in the Lysosomal PathwayPig oocyte activation using a Zn²⁺ chelator, TPEN.Developing a Triple Transgenic Cell Line for High-Efficiency Porcine Reproductive and Respiratory Syndrome Virus InfectionMouse Siglec-1 Mediates trans-Infection of Surface-bound Murine Leukemia Virus in a Sialic Acid N-Acyl Side Chain-dependent Manner.MYH9 is an Essential Factor for Porcine Reproductive and Respiratory Syndrome Virus Infection.Immortalized MH-S cells lack defining features of primary alveolar macrophages and do not support mouse pneumovirus replication.The Crystal Structure of the Fifth Scavenger Receptor Cysteine-Rich Domain of Porcine CD163 Reveals an Important Residue Involved in Porcine Reproductive and Respiratory Syndrome Virus InfectionPRRSV receptors and their roles in virus infection.Molecular cloning of porcine Siglec-3, Siglec-5 and Siglec-10, and identification of Siglec-10 as an alternative receptor for porcine reproductive and respiratory syndrome virus (PRRSV).Challenges in Veterinary Vaccine Development and Immunization.Gene editing as applied to prevention of reproductive porcine reproductive and respiratory syndrome.Replacement of Porcine CD163 Scavenger Receptor Cysteine-Rich Domain 5 with a CD163-Like Homolog Confers Resistance of Pigs to Genotype 1 but Not Genotype 2 Porcine Reproductive and Respiratory Syndrome Virus.Relationships of CD163 and CD169 positive cell numbers in the endometrium and fetal placenta with type 2 PRRSV RNA concentration in fetal thymus.Establishing Porcine Monocyte-Derived Macrophage and Dendritic Cell Systems for Studying the Interaction with PRRSV-1.Generation of murine macrophage-derived cell lines expressing porcine CD163 that support porcine reproductive and respiratory syndrome virus infection.Gene-edited pigs are protected from porcine reproductive and respiratory syndrome virus.Pharmacologic treatment of donor cells induced to have a Warburg Effect-like metabolism does not alter embryonic development in vitro or survival during early gestation when used in somatic cell nuclear transfer in pigs.Zygote injection of CRISPR/Cas9 RNA successfully modifies the target gene without delaying blastocyst development or altering the sex ratio in pigs.Porcine reproductive and respiratory syndrome virus neutralizing antibodies provide in vivo cross-protection to PRRSV1 and PRRSV2 viral challenge.Genetic resistance - an alternative for controlling PRRS?Porcine Reproductive and Respiratory Syndrome Virus Type 1.3 Lena Triggers Conventional Dendritic Cells 1 Activation and T Helper 1 Immune Response Without Infecting Dendritic CellsGenome Editing of Pigs for Agriculture and Biomedicine
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An intact sialoadhesin (Sn/SIGLEC1/CD169) is not required for attachment/internalization of the porcine reproductive and respiratory syndrome virus
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
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scientific article published on 19 June 2013
@en
vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
An intact sialoadhesin (Sn/SIG ...... and respiratory syndrome virus
@en
An intact sialoadhesin
@nl
type
label
An intact sialoadhesin (Sn/SIG ...... and respiratory syndrome virus
@en
An intact sialoadhesin
@nl
prefLabel
An intact sialoadhesin (Sn/SIG ...... and respiratory syndrome virus
@en
An intact sialoadhesin
@nl
P2093
P2860
P356
P1433
P1476
An intact sialoadhesin (Sn/SIG ...... and respiratory syndrome virus
@en
P2093
Benjamin Trible
Bhupinder Bawa
Catherine Ewen
Clifton N Murphy
Jennifer M Teson
Kristin M Whitworth
Maureen Kerrigan
Melissa S Samuel
P2860
P304
P356
10.1128/JVI.00177-13
P407
P577
2013-06-19T00:00:00Z