Hyperoxia-induced premature senescence requires p53 and pRb, but not mitochondrial matrix ROS.
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Honeybee associative learning performance and metabolic stress resilience are positively associatedCellular senescence in normal and premature lung aging.Arabidopsis RETINOBLASTOMA-RELATED is required for stem cell maintenance, cell differentiation, and lateral organ production.2-Deoxy-D-glucose treatment of endothelial cells induces autophagy by reactive oxygen species-mediated activation of the AMP-activated protein kinase.Acrolein-exposed normal human lung fibroblasts in vitro: cellular senescence, enhanced telomere erosion, and degradation of Werner's syndrome proteinMitochondrial oxidant stress increases PDE5 activity in persistent pulmonary hypertension of the newborn.The Lkb1 metabolic sensor maintains haematopoietic stem cell survival.Hyperoxia impairs alveolar formation and induces senescence through decreased histone deacetylase activity and up-regulation of p21 in neonatal mouse lung.Mitochondrial effectors of cellular senescence: beyond the free radical theory of agingHypoxia leads to Na,K-ATPase downregulation via Ca(2+) release-activated Ca(2+) channels and AMPK activationDose-dependent effects of R-sulforaphane isothiocyanate on the biology of human mesenchymal stem cells, at dietary amounts, it promotes cell proliferation and reduces senescence and apoptosis, while at anti-cancer drug doses, it has a cytotoxic effeActivation of a PGC-1-related coactivator (PRC)-dependent inflammatory stress program linked to apoptosis and premature senescence.Environmental stress, ageing and glial cell senescence: a novel mechanistic link to Parkinson's disease?Endogenous oxidative stress prevents telomerase-dependent immortalization of human endothelial cells.Alpha1-AMP-activated protein kinase regulates hypoxia-induced Na,K-ATPase endocytosis via direct phosphorylation of protein kinase C zeta.Connective Tissue Growth Factor Promotes Pulmonary Epithelial Cell Senescence and Is Associated with COPD SeverityHypoxia and senescence: the impact of oxygenation on tumor suppressionOxygen regulates molecular mechanisms of cancer progression and metastasis.Mitochondrial dysfunction in inflammatory responses and cellular senescence: pathogenesis and pharmacological targets for chronic lung diseases.Honokiol inhibits lung tumorigenesis through inhibition of mitochondrial function.PI3K/Akt/uncoupling protein 2 signaling pathway may be involved in cell senescence and apoptosis induced by angiotensin II in human vascular endothelial cells.LKB1/PEA3/ΔNp63 pathway regulates PTGS-2 (COX-2) transcription in lung cancer cells upon cigarette smoke exposureMetabolic changes in cancer cells upon suppression of MYC.Reactive oxygen species induce injury of the intestinal epithelium during hyperoxia.Sphere-Induced Rejuvenation of Swine and Human Müller Glia Is Primarily Caused by Telomere Elongation.p21(WAF1) (/Cip1) limits senescence and acinar-to-ductal metaplasia formation during pancreatitis.
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P2860
Hyperoxia-induced premature senescence requires p53 and pRb, but not mitochondrial matrix ROS.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 23 October 2008
@en
vedecký článok
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vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
Hyperoxia-induced premature se ...... not mitochondrial matrix ROS.
@en
Hyperoxia-induced premature se ...... not mitochondrial matrix ROS.
@nl
type
label
Hyperoxia-induced premature se ...... not mitochondrial matrix ROS.
@en
Hyperoxia-induced premature se ...... not mitochondrial matrix ROS.
@nl
prefLabel
Hyperoxia-induced premature se ...... not mitochondrial matrix ROS.
@en
Hyperoxia-induced premature se ...... not mitochondrial matrix ROS.
@nl
P2093
P2860
P356
P1433
P1476
Hyperoxia-induced premature se ...... not mitochondrial matrix ROS.
@en
P2093
Colleen M Snyder
Emelyn H Shroff
Eric L Bell
Frank D Weinberg
G R Scott Budinger
Goberdan P Dimri
Navdeep S Chandel
Paul T Schumacker
Tatyana A Klimova
P2860
P304
P356
10.1096/FJ.08-114256
P407
P577
2008-10-23T00:00:00Z