TREM-2 (triggering receptor expressed on myeloid cells 2) is a phagocytic receptor for bacteria. - Wikidata - awgldk - TriplyDB

TREM-2 (triggering receptor expressed on myeloid cells 2) is a phagocytic receptor for bacteria.

TREM-2 (triggering receptor expressed on myeloid cells 2) is a phagocytic receptor for bacteria.

http://www.wikidata.org/entity/Q37124881

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TREM2 in CNS homeostasis and neurodegenerative disease Macrophages in intestinal homeostasis and inflammation Mechanisms and potential therapeutic applications of microglial activation after brain injury Pathogenesis of infection in surgical patients Triggering receptor expressed on myeloid cells receptor family modulators: a patent review Stress Granules Modulate SYK to Cause Microglial Cell Dysfunction in Alzheimer's Disease.Phagocytosis of apoptotic cells in homeostasis The receptor TREML4 amplifies TLR7-mediated signaling during antiviral responses and autoimmunity TREM2 and the neuroimmunology of Alzheimer's disease Insights into TREM2 biology by network analysis of human brain gene expression data.The triggering receptor expressed on myeloid cells 2 inhibits complement component 1q effector mechanisms and exerts detrimental effects during pneumococcal pneumonia.Dual induction of TREM2 and tolerance-related transcript, Tmem176b, in amyloid transgenic mice: implications for vaccine-based therapies for Alzheimer's disease.Neurobiology of microglial action in CNS injuries: receptor-mediated signaling mechanisms and functional roles The role of the microglia in acute CNS injury.The evolving biology of microglia in Alzheimer's disease.Nuclear receptors license phagocytosis by trem2+ myeloid cells in mouse models of Alzheimer's disease.TREM2 Protein Expression Changes Correlate with Alzheimer's Disease Neurodegenerative Pathologies in Post-Mortem Temporal Cortices The expanding roles of ITAM adapters FcRgamma and DAP12 in myeloid cells.TREM-2 Receptor Expression Increases with 25(OH)D Vitamin Serum Levels in Patients with Pulmonary Sarcoidosis.Triggering Receptor Expressed on Myeloid Cells (TREM)-2 Impairs Host Defense in Experimental Melioidosis The TREM2-DAP12 signaling pathway in Nasu-Hakola disease: a molecular genetics perspective.Molecular Characteristics of High-Dose Melphalan Associated Oral Mucositis in Patients with Multiple Myeloma: A Gene Expression Study on Human Mucosa Apolipoprotein E Is a Ligand for Triggering Receptor Expressed on Myeloid Cells 2 (TREM2).TREM2 regulates microglial cell activation in response to demyelination in vivo.The FTD-like syndrome causing TREM2 T66M mutation impairs microglia function, brain perfusion, and glucose metabolism.Chronic inflammation and cancer: emerging roles of triggering receptors expressed on myeloid cells.Cerebrospinal fluid soluble TREM2 in aging and Alzheimer's disease Opposing roles of the triggering receptor expressed on myeloid cells 2 and triggering receptor expressed on myeloid cells-like transcript 2 in microglia activation.TREM2 governs Kupffer cell activation and explains belr1 genetic resistance to malaria liver stage infection Preparation, crystallization, and preliminary crystallographic analysis of wild-type and mutant human TREM-2 ectodomains linked to neurodegenerative and inflammatory diseases Microglial activation in stroke: therapeutic targets.Src-family and Syk kinases in activating and inhibitory pathways in innate immune cells: signaling cross talk.Microglial activatory (immunoreceptor tyrosine-based activation motif)- and inhibitory (immunoreceptor tyrosine-based inhibition motif)-signaling receptors for recognition of the neuronal glycocalyx.Information processing during phagocytosis.BACE1 influences debris clearance and axonal regeneration in injured peripheral nerve.Bacterial superinfection following lung inflammatory disorders.TREM2 in Alzheimer's disease.The innate immune system in Alzheimer's disease.Emerging roles for triggering receptor expressed on myeloid cells receptor family signaling in inflammatory diseases.Syk and Yea Shall Find.

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TREM-2 (triggering receptor expressed on myeloid cells 2) is a phagocytic receptor for bacteria.

http://www.wikidata.org/entity/Q37124881

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on January 2009

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

TREM-2 (triggering receptor ex ...... gocytic receptor for bacteria.

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TREM-2

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type

label

TREM-2 (triggering receptor ex ...... gocytic receptor for bacteria.

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TREM-2

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prefLabel

TREM-2 (triggering receptor ex ...... gocytic receptor for bacteria.

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TREM-2

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Journal of Cell Biology

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TREM-2 (triggering receptor ex ...... gocytic receptor for bacteria.

@en

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Catherine S Branda

http://www.w3.org/2001/XMLSchema#string

Clifford Lowell

http://www.w3.org/2001/XMLSchema#string

Elsa-Noah N'Diaye

http://www.w3.org/2001/XMLSchema#string

Jessica A Hamerman

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Lisette Nevarez

http://www.w3.org/2001/XMLSchema#string

Steven S Branda

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William E Seaman

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P2860

CD45 regulates Src family member kinase activity associated with macrophage integrin-mediated adhesion

Syk expression and novel function in a wide variety of tissues

Regulation of phagocytosis by Rho GTPases

Pattern recognition by TREM-2: binding of anionic ligands

Integrin signaling in neutrophils and macrophages uses adaptors containing immunoreceptor tyrosine-based activation motifs

A critical role for Syk in signal transduction and phagocytosis mediated by Fcgamma receptors on macrophages

Identification of two distinct mechanisms of phagocytosis controlled by different Rho GTPases

Plat-E: an efficient and stable system for transient packaging of retroviruses

Mechanisms of phagocytosis in macrophages

The Syk protein tyrosine kinase is essential for Fcgamma receptor signaling in macrophages and neutrophils

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215-223

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scholarly article

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10.1083/JCB.200808080

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2

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184

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2009-01-01T00:00:00Z

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23950894

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19171755

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2654305

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