Genetically encoded norbornene directs site-specific cellular protein labelling via a rapid bioorthogonal reaction. - Wikidata - awgldk - TriplyDB

Genetically encoded norbornene directs site-specific cellular protein labelling via a rapid bioorthogonal reaction.

Genetically encoded norbornene directs site-specific cellular protein labelling via a rapid bioorthogonal reaction.

http://www.wikidata.org/entity/Q37136587

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Linkers Having a Crucial Role in Antibody-Drug Conjugates Click chemistry in complex mixtures: bioorthogonal bioconjugation Pyrrolysyl-tRNA synthetase: an ordinary enzyme but an outstanding genetic code expansion tool Shedding light on protein folding, structural and functional dynamics by single molecule studies Bioorthogonal chemistry: strategies and recent developments Spacer-free BODIPY fluorogens in antimicrobial peptides for direct imaging of fungal infection in human tissue Structural insights into incorporation of norbornene amino acids for click modification of proteins Atom-by-atom engineering of voltage-gated ion channels: magnified insights into function and pharmacology Tetrazine-Containing Amino Acid for Peptide Modification and Live Cell Labeling A Minimal, Unstrained S-Allyl Handle for Pre-Targeting Diels-Alder Bioorthogonal Labeling in Live Cells Photo-Triggered Click Chemistry for Biological Applications Bioconjugation of therapeutic proteins and enzymes using the expanded set of genetically encoded amino acids.Optimized orthogonal translation of unnatural amino acids enables spontaneous protein double-labelling and FRET Genetically encoded optochemical probes for simultaneous fluorescence reporting and light activation of protein function with two-photon excitation.Translation system engineering in Escherichia coli enhances non-canonical amino acid incorporation into proteins.Bioorthogonal cyclization-mediated in situ self-assembly of small-molecule probes for imaging caspase activity in vivo Strain-promoted sydnone bicyclo-[6.1.0]-nonyne cycloaddition†Electronic supplementary information (ESI) available: Full experimental details, (1)H/(13)C NMR spectral data, protein synthesis and purification. See DOI: 10.1039/c3sc53332h.4R- and 4S-iodophenyl hydroxyproline, 4R-pentynoyl hydroxyproline, and S-propargyl-4-thiolphenylalanine: conformationally biased and tunable amino acids for bioorthogonal reactions.Synthesis and reactivity comparisons of 1-methyl-3-substituted cyclopropene mini-tags for tetrazine bioorthogonal reactions Chemoenzymatic site-specific reversible immobilization and labeling of proteins from crude cellular extract without prior purification using oxime and hydrazine ligation Tetrazine ligation for chemical proteomics.In situ synthesis of alkenyl tetrazines for highly fluorogenic bioorthogonal live-cell imaging probes.Proteome labeling and protein identification in specific tissues and at specific developmental stages in an animal.Photoclick chemistry: a fluorogenic light-triggered in vivo ligation reaction.Two rapid catalyst-free click reactions for in vivo protein labeling of genetically encoded strained alkene/alkyne functionalities.Genetically encoded unstrained olefins for live cell labeling with tetrazine dyes.Self-assembly of random copolymers.Genetically encoded libraries of nonstandard peptides.A Bioorthogonal Chemical Reporter of Viral Infection.Protein conjugation with genetically encoded unnatural amino acids.A genetically encoded alkyne directs palladium-mediated protein labeling on live mammalian cell surface Synthesis of non-linear protein dimers through a genetically encoded Thiol-ene reaction.Chemically tunable mucin chimeras assembled on living cells.An efficient and mild oxidant for the synthesis of s-tetrazines.Study of the Binding Energies between Unnatural Amino Acids and Engineered Orthogonal Tyrosyl-tRNA Synthetases Site-Specific Glycoconjugation of Protein via Bioorthogonal Tetrazine Cycloaddition with a Genetically Encoded trans-Cyclooctene or Bicyclononyne.Genetically encoded cyclopropene directs rapid, photoclick-chemistry-mediated protein labeling in mammalian cells.Discovery of new mutually orthogonal bioorthogonal cycloaddition pairs through computational screening Facile and stabile linkages through tyrosine: bioconjugation strategies with the tyrosine-click reaction.Genetic Encoding of bicyclononynes and trans-cyclooctenes for site-specific protein labeling in vitro and in live mammalian cells via rapid fluorogenic Diels-Alder reactions.

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P2860

Genetically encoded norbornene directs site-specific cellular protein labelling via a rapid bioorthogonal reaction.

http://www.wikidata.org/entity/Q37136587

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 05 February 2012

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Genetically encoded norbornene ...... rapid bioorthogonal reaction.

@en

Genetically encoded norbornene ...... rapid bioorthogonal reaction.

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type

label

Genetically encoded norbornene ...... rapid bioorthogonal reaction.

@en

Genetically encoded norbornene ...... rapid bioorthogonal reaction.

@nl

prefLabel

Genetically encoded norbornene ...... rapid bioorthogonal reaction.

@en

Genetically encoded norbornene ...... rapid bioorthogonal reaction.

@nl

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Nature Chemistry

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Genetically encoded norbornene ...... rapid bioorthogonal reaction.

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Alexander Deiters

http://www.w3.org/2001/XMLSchema#string

Chungjung Chou

http://www.w3.org/2001/XMLSchema#string

Jason W Chin

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Jessica Torres-Kolbus

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Kathrin Lang

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Lloyd Davis

http://www.w3.org/2001/XMLSchema#string

P2860

A fluorophore ligase for site-specific protein labeling inside living cells

Tetrazine ligation: fast bioconjugation based on inverse-electron-demand Diels-Alder reactivity

Tetrazine-based cycloadditions: application to pretargeted live cell imaging

A Biosynthetic Route to Photoclick Chemistry on Proteins

Green fluorescent protein as a marker for gene expression

An expanded eukaryotic genetic code

Specific covalent labeling of recombinant protein molecules inside live cells

A guide to choosing fluorescent proteins

Expanding the genetic code of yeast for incorporation of diverse unnatural amino acids via a pyrrolysyl-tRNA synthetase/tRNA pair

The fluorescent toolbox for assessing protein location and function

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298-304

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scholarly article

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10.1038/NCHEM.1250

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4

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4

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2012-02-05T00:00:00Z

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22437715

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3758886

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