Hepatic insulin signaling regulates VLDL secretion and atherogenesis in mice. - Wikidata - awgldk - TriplyDB

Hepatic insulin signaling regulates VLDL secretion and atherogenesis in mice.

Hepatic insulin signaling regulates VLDL secretion and atherogenesis in mice.

http://www.wikidata.org/entity/Q37143361

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Naringenin prevents dyslipidemia, apolipoprotein B overproduction, and hyperinsulinemia in LDL receptor-null mice with diet-induced insulin resistance Proatherogenic abnormalities of lipid metabolism in SirT1 transgenic mice are mediated through Creb deacetylation Targeted deletion of murine CEACAM 1 activates PI3K-Akt signaling and contributes to the expression of (Pro)renin receptor via CREB family and NF-κB transcription factors.The impact of macrophage insulin resistance on advanced atherosclerotic plaque progression.Insulin acutely inhibits intestinal lipoprotein secretion in humans in part by suppressing plasma free fatty acids Hepatic FoxO1 ablation exacerbates lipid abnormalities during hyperglycemia Znf202 affects high density lipoprotein cholesterol levels and promotes hepatosteatosis in hyperlipidemic mice.n-3 Fatty acids decrease arterial low-density lipoprotein cholesterol delivery and lipoprotein lipase levels in insulin-resistant mice Spontaneously diabetic Ins2(+/Akita):apoE-deficient mice exhibit exaggerated hypercholesterolemia and atherosclerosis Respective contributions of maternal insulin resistance and diet to metabolic and hypothalamic phenotypes of progeny A mutant allele encoding DNA binding-deficient FoxO1 differentially regulates hepatic glucose and lipid metabolism Regulation of hepatic LDL receptors by mTORC1 and PCSK9 in mice Animal models of atherosclerosis.Activation of ER stress and mTORC1 suppresses hepatic sortilin-1 levels in obese mice.Increased atherosclerosis and endothelial dysfunction in mice bearing constitutively deacetylated alleles of Foxo1 gene.Are hepatic steatosis and carotid intima media thickness associated in obese patients with normal or slightly elevated gamma-glutamyl-transferase?Cdkn2a is an atherosclerosis modifier locus that regulates monocyte/macrophage proliferation.Estrogen treatment after ovariectomy protects against fatty liver and may improve pathway-selective insulin resistance.Effect of Leptin Replacement on PCSK9 in ob/ob Mice and Female Lipodystrophic Patients.Hyperinsulinemia does not change atherosclerosis development in apolipoprotein E null mice.One day of mixed meal overfeeding reduces hepatic insulin sensitivity and increases VLDL particle but not VLDL-triglyceride secretion in overweight and obese men Expanded granulocyte/monocyte compartment in myeloid-specific triple FoxO knockout increases oxidative stress and accelerates atherosclerosis in mice Impaired hepatic insulin signalling in PON2-deficient mice: a novel role for the PON2/apoE axis on the macrophage inflammatory response.Very-low-density lipoprotein: complex particles in cardiac energy metabolism.AMP-activated protein kinase: an emerging drug target to regulate imbalances in lipid and carbohydrate metabolism to treat cardio-metabolic diseases The regulation of ApoB metabolism by insulin.Novel mechanism of blood pressure regulation by forkhead box class O1-mediated transcriptional control of hepatic angiotensinogen.Nobiletin attenuates VLDL overproduction, dyslipidemia, and atherosclerosis in mice with diet-induced insulin resistance.Effects of small interfering RNA-mediated hepatic glucagon receptor inhibition on lipid metabolism in db/db mice.Deepure Tea Improves High Fat Diet-Induced Insulin Resistance and Nonalcoholic Fatty Liver Disease.mTORC1 stimulates phosphatidylcholine synthesis to promote triglyceride secretion.A Novel Strategy to Prevent Advanced Atherosclerosis and Lower Blood Glucose in a Mouse Model of Metabolic Syndrome.

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Hepatic insulin signaling regulates VLDL secretion and atherogenesis in mice.

http://www.wikidata.org/entity/Q37143361

description

article científic

@ca

article scientifique

@fr

articolo scientifico

@it

artigo científico

@pt

bilimsel makale

@tr

scientific article published on 09 March 2009

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

Hepatic insulin signaling regulates VLDL secretion and atherogenesis in mice.

@en

Hepatic insulin signaling regulates VLDL secretion and atherogenesis in mice.

@nl

type

label

Hepatic insulin signaling regulates VLDL secretion and atherogenesis in mice.

@en

Hepatic insulin signaling regulates VLDL secretion and atherogenesis in mice.

@nl

prefLabel

Hepatic insulin signaling regulates VLDL secretion and atherogenesis in mice.

@en

Hepatic insulin signaling regulates VLDL secretion and atherogenesis in mice.

@nl

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P1433

Journal of Clinical Investigation

P1476

Hepatic insulin signaling regulates VLDL secretion and atherogenesis in mice.

@en

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Alan R Tall

http://www.w3.org/2001/XMLSchema#string

Carrie L Welch

http://www.w3.org/2001/XMLSchema#string

Chien-Ping Liang

http://www.w3.org/2001/XMLSchema#string

Marit Westerterp

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Michihiro Matsumoto

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Qizhi Wang

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Seongah Han

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Takafumi Senokuchi

http://www.w3.org/2001/XMLSchema#string

P2860

A beta-arrestin 2 signaling complex mediates lithium action on behavior

Protein kinase SGK mediates survival signals by phosphorylating the forkhead transcription factor FKHRL1 (FOXO3a)

AKT/PKB signaling: navigating downstream

The forkhead transcription factor Foxo1 (Fkhr) confers insulin sensitivity onto glucose-6-phosphatase expression

Decreased IRS-2 and increased SREBP-1c lead to mixed insulin resistance and sensitivity in livers of lipodystrophic and ob/ob mice

FoxO1 mediates insulin-dependent regulation of hepatic VLDL production in mice

Restoration of liver insulin signaling in Insr knockout mice fails to normalize hepatic insulin action.

Disruption of LDL receptor gene in transgenic SREBP-1a mice unmasks hyperlipidemia resulting from production of lipid-rich VLDL

The role of the LDL receptor in apolipoprotein B secretion.

Insulin resistance and cardiovascular disease.

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1029-1041

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scholarly article

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10.1172/JCI36523

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4

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119

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Domenico Accili

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2009-03-09T00:00:00Z

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24189199

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19273907

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2662550

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