SOAR and the polybasic STIM1 domains gate and regulate Orai channels. - Wikidata - awgldk - TriplyDB

SOAR and the polybasic STIM1 domains gate and regulate Orai channels.

SOAR and the polybasic STIM1 domains gate and regulate Orai channels.

http://www.wikidata.org/entity/Q37145533

about

POST, partner of stromal interaction molecule 1 (STIM1), targets STIM1 to multiple transporters STIM1 couples to ORAI1 via an intramolecular transition into an extended conformation A protease-independent function for SPPL3 in NFAT activation A novel EF-hand protein, CRACR2A, is a cytosolic Ca2+ sensor that stabilizes CRAC channels in T cells Proteomic mapping of ER-PM junctions identifies STIMATE as a regulator of Ca²⁺ influx STIM proteins: dynamic calcium signal transducers Ca2+ toxicity and mitochondrial damage in acute pancreatitis: translational overview STIM and Orai1 Variants in Store-Operated Calcium Entry SOCE and cancer: Recent progress and new perspectives Modulation of T Cell Metabolism and Function through Calcium Signaling Structural aspects of calcium-release activated calcium channel function Orai1 calcium channels in the vasculature Ion channels and transporters in lymphocyte function and immunity The STIM1/Orai signaling machinery Molecular regulation of CRAC channels and their role in lymphocyte function The TR (i)P to Ca²⁺ signaling just got STIMy: an update on STIM1 activated TRPC channels Store-operated Orai channels: structure and function Multifaceted roles of STIM proteins Store-independent modulation of Ca(2+) entry through Orai by Septin 7.Auto-inhibitory role of the EF-SAM domain of STIM proteins in store-operated calcium entry Crystal Structure of Calmodulin Binding Domain of Orai1 in Complex with Ca2+*Calmodulin Displays a Unique Binding Mode Crystal Structure of the Calcium Release-Activated Calcium Channel Orai Structural and mechanistic insights into the activation of Stromal interaction molecule 1 (STIM1)The inhibitory helix controls the intramolecular conformational switching of the C-terminus of STIM1 STIM1/Orai1 coiled-coil interplay in the regulation of store-operated calcium entry Calcium Dyshomeostasis in Tubular Aggregate Myopathy Diseases caused by mutations in ORAI1 and STIM1 Di-arginine signals and the K-rich domain retain the Ca²⁺ sensor STIM1 in the endoplasmic reticulum Inside-out Ca(2+) signalling prompted by STIM1 conformational switch.STIM1 gates the store-operated calcium channel ORAI1 in vitro Initial activation of STIM1, the regulator of store-operated calcium entry An essential and NSF independent role for α-SNAP in store-operated calcium entry Redox regulation of store-operated Ca2+ entry Comprehensive analysis and identification of the human STIM1 domains for structural and functional studies Conformational Changes in the Orai1 C-Terminus Evoked by STIM1 Binding STIM1 is necessary for store-operated calcium entry in turning growth cones Intracellular Ca2+ signaling and store-operated Ca2+ entry are required in Drosophila neurons for flight STIMulating store-operated Ca(2+) entry.Activation of TRPC1 by STIM1 in ER-PM microdomains involves release of the channel from its scaffold caveolin-1.Single-molecule analysis of diffusion and trapping of STIM1 and Orai1 at endoplasmic reticulum-plasma membrane junctions.

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P2860

SOAR and the polybasic STIM1 domains gate and regulate Orai channels.

http://www.wikidata.org/entity/Q37145533

description

article científic

@ca

article scientifique

@fr

articolo scientifico

@it

artigo científico

@pt

bilimsel makale

@tr

scientific article published on February 2009

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

SOAR and the polybasic STIM1 domains gate and regulate Orai channels.

@en

SOAR and the polybasic STIM1 domains gate and regulate Orai channels.

@nl

type

label

SOAR and the polybasic STIM1 domains gate and regulate Orai channels.

@en

SOAR and the polybasic STIM1 domains gate and regulate Orai channels.

@nl

prefLabel

SOAR and the polybasic STIM1 domains gate and regulate Orai channels.

@en

SOAR and the polybasic STIM1 domains gate and regulate Orai channels.

@nl

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P1433

Nature Cell Biology

P1476

SOAR and the polybasic STIM1 domains gate and regulate Orai channels.

@en

P2093

Joseph P Yuan

http://www.w3.org/2001/XMLSchema#string

Michael R Dorwart

http://www.w3.org/2001/XMLSchema#string

Paul F Worley

http://www.w3.org/2001/XMLSchema#string

Shmuel Muallem

http://www.w3.org/2001/XMLSchema#string

Weizhong Zeng

http://www.w3.org/2001/XMLSchema#string

Young-Jin Choi

http://www.w3.org/2001/XMLSchema#string

P2860

Large store-operated calcium selective currents due to co-expression of Orai1 or Orai2 with the intracellular calcium sensor, Stim1

Homer binds TRPC family channels and is required for gating of TRPC1 by IP3 receptors

STIM is a Ca2+ sensor essential for Ca2+-store-depletion-triggered Ca2+ influx

CRACM1 is a plasma membrane protein essential for store-operated Ca2+ entry

Amplification of CRAC current by STIM1 and CRACM1 (Orai1)

Genome-wide RNAi screen of Ca(2+) influx identifies genes that regulate Ca(2+) release-activated Ca(2+) channel activity

STIM1 heteromultimerizes TRPC channels to determine their function as store-operated channels

STIM1, an essential and conserved component of store-operated Ca2+ channel function

STIM1 gates TRPC channels, but not Orai1, by electrostatic interaction

Mapping the interacting domains of STIM1 and Orai1 in Ca2+ release-activated Ca2+ channel activation

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337-343

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scholarly article

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10.1038/NCB1842

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P433

3

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11

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2009-02-01T00:00:00Z

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23964636

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19182790

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2663385

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