Genome-wide RNAi screen of Ca(2+) influx identifies genes that regulate Ca(2+) release-activated Ca(2+) channel activity - Wikidata - awgldk - TriplyDB

Genome-wide RNAi screen of Ca(2+) influx identifies genes that regulate Ca(2+) release-activated Ca(2+) channel activity

Genome-wide RNAi screen of Ca(2+) influx identifies genes that regulate Ca(2+) release-activated Ca(2+) channel activity

http://www.wikidata.org/entity/Q24548526

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Large store-operated calcium selective currents due to co-expression of Orai1 or Orai2 with the intracellular calcium sensor, Stim1 STIM2 protein mediates distinct store-dependent and store-independent modes of CRAC channel activation STIM1 couples to ORAI1 via an intramolecular transition into an extended conformation A protease-independent function for SPPL3 in NFAT activation A novel EF-hand protein, CRACR2A, is a cytosolic Ca2+ sensor that stabilizes CRAC channels in T cells Proteomic mapping of ER-PM junctions identifies STIMATE as a regulator of Ca²⁺ influx Genomic screening with RNAi: results and challenges STIM proteins: dynamic calcium signal transducers Dual functions for the endoplasmic reticulum calcium sensors STIM1 and STIM2 in T cell activation and tolerance STIM1 heteromultimerizes TRPC channels to determine their function as store-operated channels T cell activation Coupling of STIM1 to store-operated Ca2+ entry through its constitutive and inducible movement in the endoplasmic reticulum.PhenomicDB: a new cross-species genotype/phenotype resource STIM and Orai1 Variants in Store-Operated Calcium Entry The endoplasmic reticulum: structure, function and response to cellular signaling Molecular identification of the CRAC channel by altered ion selectivity in a mutant of Orai Regulation of transient receptor potential channels by the phospholipase C pathway Structural aspects of calcium-release activated calcium channel function Phospholipase C signaling and calcium influx Ion channels and transporters in lymphocyte function and immunity Molecular mechanism of pancreatic and salivary gland fluid and HCO3 secretion Permeation, selectivity and gating in store-operated CRAC channels Orai3--the 'exceptional' Orai?The STIM1/Orai signaling machinery Molecular regulation of CRAC channels and their role in lymphocyte function Emerging roles of L-type voltage-gated and other calcium channels in T lymphocytes Orai channels - new insights, new ideas Phosphoinositides: tiny lipids with giant impact on cell regulation Store-operated Orai channels: structure and function Multifaceted roles of STIM proteins Calcium influx pathways in breast cancer: opportunities for pharmacological intervention Non-stimulated, agonist-stimulated and store-operated Ca2+ influx in MDA-MB-468 breast cancer cells and the effect of EGF-induced EMT on calcium entry Dynamic formation of ER-PM junctions presents a lipid phosphatase to regulate phosphoinositides Store-independent modulation of Ca(2+) entry through Orai by Septin 7.Nanoscale patterning of STIM1 and Orai1 during store-operated Ca2+ entry Auto-inhibitory role of the EF-SAM domain of STIM proteins in store-operated calcium entry Crystal Structure of Calmodulin Binding Domain of Orai1 in Complex with Ca2+*Calmodulin Displays a Unique Binding Mode Crystal Structure of the Calcium Release-Activated Calcium Channel Orai STIM1/Orai1 coiled-coil interplay in the regulation of store-operated calcium entry Pathophysiological Significance of Store-Operated Calcium Entry in Megakaryocyte Function: Opening New Paths for Understanding the Role of Calcium in Thrombopoiesis

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Genome-wide RNAi screen of Ca(2+) influx identifies genes that regulate Ca(2+) release-activated Ca(2+) channel activity

http://www.wikidata.org/entity/Q24548526

description

2006 nî lūn-bûn

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2006 թուականի Յունիսին հրատարակուած գիտական յօդուած

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2006 թվականի հունիսին հրատարակված գիտական հոդված

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2006年の論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年论文

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Genome-wide RNAi screen of Ca( ...... ivated Ca(2+) channel activity

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Genome-wide RNAi screen of Ca( ...... ivated Ca(2+) channel activity

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Genome-wide RNAi screen of Ca( ...... ivated Ca(2+) channel activity

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Genome-wide RNAi screen of Ca( ...... ivated Ca(2+) channel activity

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Genome-wide RNAi screen of Ca( ...... ivated Ca(2+) channel activity

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Genome-wide RNAi screen of Ca( ...... ivated Ca(2+) channel activity

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Genome-wide RNAi screen of Ca( ...... ivated Ca(2+) channel activity

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Genome-wide RNAi screen of Ca( ...... ivated Ca(2+) channel activity

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Genome-wide RNAi screen of Ca( ...... ivated Ca(2+) channel activity

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Proceedings of the National Academy of Sciences of the United States of America

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Genome-wide RNAi screen of Ca( ...... ivated Ca(2+) channel activity

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Andriy V Yeromin

http://www.w3.org/2001/XMLSchema#string

Aubin Penna

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Jack Roos

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Kenneth A Stauderman

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Michael D Cahalan

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Olga Safrina

http://www.w3.org/2001/XMLSchema#string

Shenyuan L Zhang

http://www.w3.org/2001/XMLSchema#string

Xiang H-F Zhang

http://www.w3.org/2001/XMLSchema#string

Ying Yu

http://www.w3.org/2001/XMLSchema#string

P2860

STIM is a Ca2+ sensor essential for Ca2+-store-depletion-triggered Ca2+ influx

CRACM1 is a plasma membrane protein essential for store-operated Ca2+ entry

STIM1 is a Ca2+ sensor that activates CRAC channels and migrates from the Ca2+ store to the plasma membrane

STIM1 has a plasma membrane role in the activation of store-operated Ca(2+) channels

STIM1, an essential and conserved component of store-operated Ca2+ channel function

A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function

Store-operated calcium channels

Large-scale analysis of gene function in Caenorhabditis elegans by high-throughput RNAi

Gene silencing of selected calcium-signalling molecules in a Drosophila cell line using double-stranded RNA interference.

Genome-wide RNAi analysis of JAK/STAT signaling components in Drosophila.

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16751269

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1482614

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