RLIP76: A novel glutathione-conjugate and multi-drug transporter. - Wikidata - awgldk - TriplyDB

RLIP76: A novel glutathione-conjugate and multi-drug transporter.

RLIP76: A novel glutathione-conjugate and multi-drug transporter.

http://www.wikidata.org/entity/Q37146979

about

A central role of RLIP76 in regulation of glycemic control.Glutathionylated 4-hydroxy-2-(E)-alkenal enantiomers in rat organs and their contributions toward the disposal of 4-hydroxy-2-(E)-nonenal in rat liver.Didymin: an orally active citrus flavonoid for targeting neuroblastoma.Glutathionylated products of lipid peroxidation: A novel mechanism of adipocyte to macrophage signaling RLIP76, a glutathione-conjugate transporter, plays a major role in the pathogenesis of metabolic syndrome.LIM kinase-2 induces programmed necrotic neuronal death via dysfunction of DRP1-mediated mitochondrial fission.Emerging treatments in lung cancer - targeting the RLIP76 molecular transporter.Glutathione-conjugate transport by RLIP76 is required for clathrin-dependent endocytosis and chemical carcinogenesis.Overexpression of RLIP76 Required for Proliferation in Meningioma Is Associated with Recurrence.Inflammation Modulates RLIP76/RALBP1 Electrophile-Glutathione Conjugate Transporter and Housekeeping Genes in Human Blood-Brain Barrier Endothelial Cells.The RalB small GTPase mediates formation of invadopodia through a GTPase-activating protein-independent function of the RalBP1/RLIP76 effector Protein carbonylation and metabolic control systems.Protein carbonylation, mitochondrial dysfunction, and insulin resistance.Antioxidant role of glutathione S-transferases: 4-Hydroxynonenal, a key molecule in stress-mediated signaling Roles of the lipid peroxidation product 4-hydroxynonenal in obesity, the metabolic syndrome, and associated vascular and neurodegenerative disorders.Glutathionylated lipid aldehydes are products of adipocyte oxidative stress and activators of macrophage inflammation.RLIP76 Targeted Therapy for Kidney Cancer Chemistry and biochemistry of lipid peroxidation products.HNF1β drives glutathione (GSH) synthesis underlying intrinsic carboplatin resistance of ovarian clear cell carcinoma (OCCC).Targeting the mercapturic acid pathway and vicenin-2 for prevention of prostate cancer.RLIP76 Inhibition: A Promising Developmental Therapy for Neuroblastoma.Modulation of doxorubicin resistance by the glucose-6-phosphate dehydrogenase activity.RLIP76: a target for kidney cancer therapy.

P2860

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P2860

RLIP76: A novel glutathione-conjugate and multi-drug transporter.

http://www.wikidata.org/entity/Q37146979

description

article científic

@ca

article scientifique

@fr

articolo scientifico

@it

artigo científico

@pt

bilimsel makale

@tr

scientific article published on 15 October 2008

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

RLIP76: A novel glutathione-conjugate and multi-drug transporter.

@en

RLIP76: A novel glutathione-conjugate and multi-drug transporter.

@nl

type

label

RLIP76: A novel glutathione-conjugate and multi-drug transporter.

@en

RLIP76: A novel glutathione-conjugate and multi-drug transporter.

@nl

prefLabel

RLIP76: A novel glutathione-conjugate and multi-drug transporter.

@en

RLIP76: A novel glutathione-conjugate and multi-drug transporter.

@nl

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J.BCP.2008.10.006

P1433

Biochemical Pharmacology

P1476

RLIP76: A novel glutathione-conjugate and multi-drug transporter.

@en

P2093

Cherice Roth

http://www.w3.org/2001/XMLSchema#string

Jyotsana Singhal

http://www.w3.org/2001/XMLSchema#string

Sharad S Singhal

http://www.w3.org/2001/XMLSchema#string

Sushma Yadav

http://www.w3.org/2001/XMLSchema#string

P2860

Novel function of human RLIP76: ATP-dependent transport of glutathione conjugates and doxorubicin

RLIP76 is the major ATP-dependent transporter of glutathione-conjugates and doxorubicin in human erythrocytes

The central proline rich region of POB1/REPS2 plays a regulatory role in epidermal growth factor receptor endocytosis by binding to 14-3-3 and SH3 domain-containing proteins

Bcr encodes a GTPase-activating protein for p21rac

Identification and characterization of a novel protein interacting with Ral-binding protein 1, a putative effector protein of Ral

Bridging Ral GTPase to Rho pathways. RLIP76, a Ral effector with CDC42/Rac GTPase-activating protein activity

Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line

Small G protein Ral and its downstream molecules regulate endocytosis of EGF and insulin receptors

Identification and characterization of Ral-binding protein 1, a potential downstream target of Ral GTPases

Solution structure of the Eps15 homology domain of a human POB1 (partner of RalBP1)

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761-769

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scholarly article

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10.1016/J.BCP.2008.10.006

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5

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18983828

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2664079

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