Roles of the lipid peroxidation product 4-hydroxynonenal in obesity, the metabolic syndrome, and associated vascular and neurodegenerative disorders.
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Vitamins C and E: beneficial effects from a mechanistic perspective4-Hydroxy-nonenal-A Bioactive Lipid Peroxidation ProductCell death and diseases related to oxidative stress: 4-hydroxynonenal (HNE) in the balanceAdaptive cellular stress pathways as therapeutic targets of dietary phytochemicals: focus on the nervous systemMitochondria as a source and target of lipid peroxidation products in healthy and diseased heartProtein modifications by electrophilic lipoxidation products: adduct formation, chemical strategies and tandem mass spectrometry for their detection and identificationRole of physiological levels of 4-hydroxynonenal on adipocyte biology: implications for obesity and metabolic syndrome.Lipid peroxidation, nitric oxide metabolites, and their ratio in a group of subjects with metabolic syndrome.Lipid peroxidation: production, metabolism, and signaling mechanisms of malondialdehyde and 4-hydroxy-2-nonenalRecruiting adaptive cellular stress responses for successful brain ageing.Both aerobic exercise and resveratrol supplementation attenuate doxorubicin-induced cardiac injury in mice.Pathological aspects of lipid peroxidation.GLP-1 receptor stimulation reduces amyloid-beta peptide accumulation and cytotoxicity in cellular and animal models of Alzheimer's disease.Metabolic syndrome as a risk factor for neurological disorders.In vivo pancreatic β-cell-specific expression of antiaging gene Klotho: a novel approach for preserving β-cells in type 2 diabetesGene expression profiling unravels cancer-related hepatic molecular signatures in steatohepatitis but not in steatosisThe role of lipid peroxidation products and oxidative stress in activation of the canonical wingless-type MMTV integration site (WNT) pathway in a rat model of diabetic retinopathyCatabolism of (2E)-4-hydroxy-2-nonenal via ω- and ω-1-oxidation stimulated by ketogenic diet.Glycoxidative stress and cardiovascular complications in experimentally-induced diabetes: effects of antioxidant treatmentProlonged exposure of cortical neurons to oligomeric amyloid-β impairs NMDA receptor function via NADPH oxidase-mediated ROS production: protective effect of green tea (-)-epigallocatechin-3-gallate.Pathophysiology, treatment, and animal and cellular models of human ischemic stroke.Impaired adaptive cellular responses to oxidative stress and the pathogenesis of Alzheimer's diseaseIncreased 4-hydroxynonenal formation contributes to obesity-related lipolytic activation in adipocytes.Gender differences in Nociceptin/Orphanin FQ-induced food intake in strains derived from rats prone (WOKW) and resistant (Dark Agouti) to metabolic syndrome: a possible involvement of the cocaine- and amphetamine-regulated transcript system.Nicotinamide mononucleotide, a key NAD(+) intermediate, treats the pathophysiology of diet- and age-induced diabetes in mice.Insight into the impact of dietary saturated fat on tissue-specific cellular processes underlying obesity-related diseases.Combined exercise and insulin-like growth factor-1 supplementation induces neurogenesis in old rats, but do not attenuate age-associated DNA damageLowering the dietary omega-6: omega-3 does not hinder nonalcoholic fatty-liver disease development in a murine model.Integrated Haematological Profiles of Redox Status, Lipid, and Inflammatory Protein Biomarkers in Benign Obesity and Unhealthy Obesity with Metabolic Syndrome.Src Tyrosine Kinase Activation by 4-Hydroxynonenal Upregulates p38, ERK/AP-1 Signaling and COX-2 Expression in YPEN-1 Cells.A Triterpenoid Inhibited Hormone-Induced Adipocyte Differentiation and Alleviated Dexamethasone-Induced Insulin Resistance in 3T3-L1 adipocytes.Oxidative and endoplasmic reticulum stresses mediate apoptosis induced by modified LDL in human retinal Müller cellsPKC-ALDH2 Pathway Plays a Novel Role in Adipocyte Differentiation.Integrating cytosolic phospholipase A₂ with oxidative/nitrosative signaling pathways in neurons: a novel therapeutic strategy for AD.Association between History of Dental Amalgam Fillings and Risk of Parkinson's Disease: A Population-Based Retrospective Cohort Study in Taiwan.Dietary oxidized n-3 PUFA induce oxidative stress and inflammation: role of intestinal absorption of 4-HHE and reactivity in intestinal cells.Ablation of ceramide synthase 2 causes chronic oxidative stress due to disruption of the mitochondrial respiratory chainPeptidyl-prolyl cis/trans-isomerase A1 (Pin1) is a target for modification by lipid electrophiles.Stop signs in hippocampal insulin signaling: the role of insulin resistance in structural, functional and behavioral deficits.Mitochondrial aldehyde dehydrogenase-2 activation prevents β-amyloid-induced endothelial cell dysfunction and restores angiogenesis.
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Roles of the lipid peroxidation product 4-hydroxynonenal in obesity, the metabolic syndrome, and associated vascular and neurodegenerative disorders.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
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artigo científico
@pt
bilimsel makale
@tr
scientific article published on 19 July 2009
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vedecký článok
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vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
@cs
name
Roles of the lipid peroxidatio ...... d neurodegenerative disorders.
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Roles of the lipid peroxidatio ...... d neurodegenerative disorders.
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type
label
Roles of the lipid peroxidatio ...... d neurodegenerative disorders.
@en
Roles of the lipid peroxidatio ...... d neurodegenerative disorders.
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prefLabel
Roles of the lipid peroxidatio ...... d neurodegenerative disorders.
@en
Roles of the lipid peroxidatio ...... d neurodegenerative disorders.
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P2860
P921
P1476
Roles of the lipid peroxidatio ...... d neurodegenerative disorders.
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P2093
Mark P Mattson
P2860
P304
P356
10.1016/J.EXGER.2009.07.003
P577
2009-07-19T00:00:00Z