Sodium-coupled monocarboxylate transporters in normal tissues and in cancer. - Wikidata - awgldk - TriplyDB

Sodium-coupled monocarboxylate transporters in normal tissues and in cancer.

Sodium-coupled monocarboxylate transporters in normal tissues and in cancer.

http://www.wikidata.org/entity/Q37150883

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SLC transporters as a novel class of tumour suppressors: identity, function and molecular mechanisms Endogenous voltage gradients as mediators of cell-cell communication: strategies for investigating bioelectrical signals during pattern formation Cellular and molecular pathways through which commensal bacteria modulate sensitization to dietary antigens The Concise Guide to PHARMACOLOGY 2013/14: transporters.TRAP-seq Profiling and RNAi-Based Genetic Screens Identify Conserved Glial Genes Required for Adult Drosophila Behavior.The hypophagic response to heat stress is not mediated by GPR109A or peripheral β-OH butyrate Interaction of dietary fatty acids with tumour necrosis factor family cytokines during colon inflammation and cancer.Tumor metabolism of lactate: the influence and therapeutic potential for MCT and CD147 regulation.Monocarboxylate transporter-mediated transport of gamma-hydroxybutyric acid in human intestinal Caco-2 cells Mechanistic modeling of monocarboxylate transporter-mediated toxicokinetic/toxicodynamic interactions between γ-hydroxybutyrate and L-lactate.Role of monocarboxylate transporters in drug delivery to the brain.Metabolomics of ApcMin/+ mice genetically susceptible to intestinal cancer SLC5A8 gene, a transporter of butyrate: a gut flora metabolite, is frequently methylated in African American colon adenomas Mechanistic toxicokinetic model for gamma-hydroxybutyric acid: inhibition of active renal reabsorption as a potential therapeutic strategy.Bioenergetic characterization of mouse podocytes.The probiotic Lactobacillus plantarum counteracts TNF-{alpha}-induced downregulation of SMCT1 expression and function.The monocarboxylate transporter family--Structure and functional characterization.Impact of the metabolic activity of Streptococcus thermophilus on the colon epithelium of gnotobiotic rats.Endogenous Voltage Potentials and the Microenvironment: Bioelectric Signals that Reveal, Induce and Normalize Cancer.Functional characterization of 5-oxoproline transport via SLC16A1/MCT1 SCFA transport in rat duodenum.Pathobiology and potential therapeutic value of intestinal short-chain fatty acids in gut inflammation and obesity.Role of SLC5A8, a plasma membrane transporter and a tumor suppressor, in the antitumor activity of dichloroacetate.Transport via SLC5A8 (SMCT1) is obligatory for 2-oxothiazolidine-4-carboxylate to enhance glutathione production in retinal pigment epithelial cells Protein expressions and genetic variations of SLC5A8 in prostate cancer risk and aggressiveness A Novel Monocarboxylate Transporter Inhibitor as a Potential Treatment Strategy for γ-Hydroxybutyric Acid Overdose.γ-Hydroxybutyrate blood/plasma partitioning: effect of physiologic pH on transport by monocarboxylate transporters.Metabolism as a key to histone deacetylase inhibition.Whole-exome sequencing and an iPSC-derived cardiomyocyte model provides a powerful platform for gene discovery in left ventricular hypertrophy Significance of glycolytic metabolism-related protein expression in colorectal cancer, lymph node and hepatic metastasis.SLC5A8 nuclear translocation and loss of expression are associated with poor outcome in pancreatic ductal adenocarcinoma.An In Silico Knockout Model for Gastrointestinal Absorption Using a Systems Pharmacology Approach - Development and Application for Ketones.Loss of Hfe leads to progression of tumor phenotype in primary retinal pigment epithelial cells.Gene silencing of SLC5A8 identified by genome-wide methylation profiling in lung cancer Semi-mechanistic kidney model incorporating physiologically-relevant fluid reabsorption and transporter-mediated renal reabsorption: pharmacokinetics of γ-hydroxybutyric acid and L-lactate in rats Effects of monocarboxylate transporter inhibition on the oral toxicokinetics/toxicodynamics of γ-hydroxybutyrate and γ-butyrolactone The plasma membrane transporter SLC5A8 suppresses tumour progression through depletion of survivin without involving its transport function.Molecular mechanism of SLC5A8 inactivation in breast cancer Helicobacter pylori Infection Is Associated with Decreased Expression of SLC5A8, a Cancer Suppressor Gene, in Young Children.Reprogramming cells and tissue patterning via bioelectrical pathways: molecular mechanisms and biomedical opportunities

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Sodium-coupled monocarboxylate transporters in normal tissues and in cancer.

http://www.wikidata.org/entity/Q37150883

description

article científic

@ca

article scientifique

@fr

articolo scientifico

@it

artigo científico

@pt

bilimsel makale

@tr

scientific article published on 02 April 2008

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

Sodium-coupled monocarboxylate transporters in normal tissues and in cancer.

@en

Sodium-coupled monocarboxylate transporters in normal tissues and in cancer.

@nl

type

label

Sodium-coupled monocarboxylate transporters in normal tissues and in cancer.

@en

Sodium-coupled monocarboxylate transporters in normal tissues and in cancer.

@nl

prefLabel

Sodium-coupled monocarboxylate transporters in normal tissues and in cancer.

@en

Sodium-coupled monocarboxylate transporters in normal tissues and in cancer.

@nl

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S12248-008-9022-Y

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The AAPS Journal

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Sodium-coupled monocarboxylate transporters in normal tissues and in cancer.

@en

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Elangovan Gopal

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Muthusamy Thangaraju

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Pamela M Martin

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Puttur D Prasad

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Seiji Miyauchi

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Shiro Itagaki

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P2860

Defective adipocyte differentiation in mice lacking the C/EBPbeta and/or C/EBPdelta gene.

Na(+)/monocarboxylate transport (SMCT) protein expression correlates with survival in colon cancer: molecular characterization of SMCT

SLC5A8, a sodium transporter, is a tumor suppressor gene silenced by methylation in human colon aberrant crypt foci and cancers

The SLC16 gene family-from monocarboxylate transporters (MCTs) to aromatic amino acid transporters and beyond

Functional identification of SLC5A8, a tumor suppressor down-regulated in colon cancer, as a Na(+)-coupled transporter for short-chain fatty acids

Oxidative metabolism in cancer growth

Transport of nicotinate and structurally related compounds by human SMCT1 (SLC5A8) and its relevance to drug transport in the mammalian intestinal tract

SLC5A8 (SMCT1)-mediated transport of butyrate forms the basis for the tumor suppressive function of the transporter

The cancer cell's "power plants" as promising therapeutic targets: an overview

Cloning and functional identification of slc5a12 as a sodium-coupled low-affinity transporter for monocarboxylates (SMCT2)

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s12248-008-9022-y

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193-199

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scholarly article

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10.1208/S12248-008-9022-Y

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P433

1

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10

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Vadivel Ganapathy

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2008-04-02T00:00:00Z

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5404966

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1033554556

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2751467

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