The oncogenic LIM-only transcription factor Lmo2 regulates angiogenesis but not vasculogenesis in mice.
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Overexpression of LMO4 induces mammary hyperplasia, promotes cell invasion, and is a predictor of poor outcome in breast cancerStructural basis for the recognition of ldb1 by the N-terminal LIM domains of LMO2 and LMO4Specification and function of hemogenic endothelium during embryogenesisThe hepatitis C virus internal ribosome entry site facilitates efficient protein synthesis in blood vessel endothelium during tumour angiogenesisSolution structure of a tethered Lmo2LIM2/Ldb1LIDcomplexConformational flexibility of the oncogenic protein LMO2 primes the formation of the multi-protein transcription complexThe LIM-only protein DRAL/FHL2 interacts with and is a corepressor for the promyelocytic leukemia zinc finger proteinSCL/tal-1-dependent process determines a competence to select the definitive hematopoietic lineage prior to endothelial differentiationImmune-related zinc finger gene ZFAT is an essential transcriptional regulator for hematopoietic differentiation in blood islandsNull mutation of the Lmo4 gene or a combined null mutation of the Lmo1/Lmo3 genes causes perinatal lethality, and Lmo4 controls neural tube development in miceDefective neural tube closure and anteroposterior patterning in mice lacking the LIM protein LMO4 or its interacting partner Deaf-1Angiopoietin-2 is a direct transcriptional target of TAL1, LYL1 and LMO2 in endothelial cellsA strategy for full interrogation of prognostic gene expression patterns: exploring the biology of diffuse large B cell lymphomaMulti-organ expression profiling uncovers a gene module in coronary artery disease involving transendothelial migration of leukocytes and LIM domain binding 2: the Stockholm Atherosclerosis Gene Expression (STAGE) study.Cancer genomics identifies regulatory gene networks associated with the transition from dysplasia to advanced lung adenocarcinomas induced by c-Raf-1.Homo-binding character of LMO2 isoforms and their both synergic and antagonistic functions in regulating hematopoietic-related target genes.miR-223 and miR-142 attenuate hematopoietic cell proliferation, and miR-223 positively regulates miR-142 through LMO2 isoforms and CEBP-β.Transcriptional control of endothelial cell development.Kaposi's sarcoma-associated herpesvirus-induced upregulation of the c-kit proto-oncogene, as identified by gene expression profiling, is essential for the transformation of endothelial cellsThe transcription factor LMO2 is a robust marker of vascular endothelium and vascular neoplasms and selected other entities.PRDM1/Blimp1 downregulates expression of germinal center genes LMO2 and HGALThe oncoprotein LMO2 is expressed in normal germinal-center B cells and in human B-cell lymphomas.TAL-1/SCL and its partners E47 and LMO2 up-regulate VE-cadherin expression in endothelial cells.Malignant and nonmalignant gene signatures in squamous head and neck cancerThe LIM-only transcription factor LMO2 determines tumorigenic and angiogenic traits in glioma stem cells.Identification of LMO2 transcriptome and interactome in diffuse large B-cell lymphoma.LIM-Only Protein 4 (LMO4) and LIM Domain Binding Protein 1 (LDB1) Promote Growth and Metastasis of Human Head and Neck Cancer (LMO4 and LDB1 in Head and Neck Cancer).LIM domain only 2 protein expression, LMO2 germline genetic variation, and overall survival in diffuse large B-cell lymphoma in the pre-rituximab era.High expression of LMO2 predicts a favorable outcome in adult patients with BCR/ABL negative B-cell acute lymphoblastic leukemia.Combinatorial regulation of novel erythroid gene expression in zebrafish.Etv2 is expressed in the yolk sac hematopoietic and endothelial progenitors and regulates Lmo2 gene expressionActivated N-Ras signaling regulates arterial-venous specification in zebrafishCell signaling directing the formation and function of hemogenic endothelium during murine embryogenesis.GATA2 and Lmo2 control angiogenesis and lymphangiogenesis via direct transcriptional regulation of neuropilin-2.Epstein-Barr virus infection and expression of B-cell oncogenic markers in HIV-related diffuse large B-cell Lymphoma.LMO2 attenuates tumor growth by targeting the Wnt signaling pathway in breast and colorectal cancer.LIM Domain Only 2 Regulates Endothelial Proliferation, Angiogenesis, and Tissue Regeneration.HOX-mediated LMO2 expression in embryonic mesoderm is recapitulated in acute leukaemias.LMO4 is a prognostic marker involved in cell migration and invasion in non-small-cell lung cancer.LMO2 Enhances Lamellipodia/Filopodia Formation in Basal-Type Breast Cancer Cells by Mediating ARP3-Profilin1 Interaction.
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P2860
The oncogenic LIM-only transcription factor Lmo2 regulates angiogenesis but not vasculogenesis in mice.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on January 2000
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
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name
The oncogenic LIM-only transcr ...... ut not vasculogenesis in mice.
@en
The oncogenic LIM-only transcr ...... ut not vasculogenesis in mice.
@nl
type
label
The oncogenic LIM-only transcr ...... ut not vasculogenesis in mice.
@en
The oncogenic LIM-only transcr ...... ut not vasculogenesis in mice.
@nl
prefLabel
The oncogenic LIM-only transcr ...... ut not vasculogenesis in mice.
@en
The oncogenic LIM-only transcr ...... ut not vasculogenesis in mice.
@nl
P2093
P2860
P356
P1476
The oncogenic LIM-only transcr ...... ut not vasculogenesis in mice.
@en
P2093
P2860
P304
P356
10.1073/PNAS.97.1.320
P407
P577
2000-01-01T00:00:00Z