Hyaluronan-mediated CD44 activation of RhoGTPase signaling and cytoskeleton function promotes tumor progression.
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Hyaluronan synthase 2 (HAS2) promotes breast cancer cell invasion by suppression of tissue metalloproteinase inhibitor 1 (TIMP-1)Subtype specific elevated expression of hyaluronidase-1 (HYAL-1) in epithelial ovarian cancerRole of moesin in hyaluronan induced cell migration in glioblastoma multiformeHyaluronan-mediated CD44 interaction with p300 and SIRT1 regulates beta-catenin signaling and NFkappaB-specific transcription activity leading to MDR1 and Bcl-xL gene expression and chemoresistance in breast tumor cellsHyaluronan-CD44 interaction promotes c-Src-mediated twist signaling, microRNA-10b expression, and RhoA/RhoC up-regulation, leading to Rho-kinase-associated cytoskeleton activation and breast tumor cell invasionThe biology of CD44 and HCELL in hematopoiesis: the 'step 2-bypass pathway' and other emerging perspectivesCD44 variant isoforms in head and neck squamous cell carcinoma progressionThe Importance of CD44 as a Stem Cell Biomarker and Therapeutic Target in CancerMatrix Hyaluronan Promotes Specific MicroRNA Upregulation Leading to Drug Resistance and Tumor ProgressionThe immunological effect of hyaluronan in tumor angiogenesisNovel endogenous angiogenesis inhibitors and their therapeutic potentialPrognostic value of CD44 expression in renal cell carcinoma: a systematic review and meta-analysisGlioblastoma: a pathogenic crosstalk between tumor cells and pericytesCD44, Hyaluronan, the Hematopoietic Stem Cell, and Leukemia-Initiating CellsOrganizing the cell cortex: the role of ERM proteinsMatrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs): Positive and negative regulators in tumor cell adhesionInteraction of low molecular weight hyaluronan with CD44 and toll-like receptors promotes the actin filament-associated protein 110-actin binding and MyD88-NFκB signaling leading to proinflammatory cytokine/chemokine production and breast tumor invaCD44v6 dependence of premetastatic niche preparation by exosomesCD147, CD44, and the epidermal growth factor receptor (EGFR) signaling pathway cooperate to regulate breast epithelial cell invasiveness.Hyaluronan, CD44, and emmprin regulate lactate efflux and membrane localization of monocarboxylate transporters in human breast carcinoma cellsCD44 is a marker for the outer pillar cells in the early postnatal mouse inner ear.Inhibition of Functional Hyaluronan-CD44 Interactions in CD133-positive Primary Human Ovarian Carcinoma Cells by Small Hyaluronan Oligosaccharides.CD44: a novel synaptic cell adhesion molecule regulating structural and functional plasticity of dendritic spines.CD44 and its ligand hyaluronan as potential biomarkers in malignant pleural mesothelioma: evidence and perspectives.CD44 expression is developmentally regulated in the mouse lens and increases in the lens epithelium after injury.A case of cervical cancer expressed three mRNA variant of Hyaluronan-mediated motility receptor.Reduction of hyaluronan-CD44-mediated growth, migration, and cisplatin resistance in head and neck cancer due to inhibition of Rho kinase and PI-3 kinase signaling.The role of a new CD44st in increasing the invasion capability of the human breast cancer cell line MCF-7.Targeting surface nucleolin with multivalent HB-19 and related Nucant pseudopeptides results in distinct inhibitory mechanisms depending on the malignant tumor cell typeTransactivation of the receptor-tyrosine kinase ephrin receptor A2 is required for the low molecular weight hyaluronan-mediated angiogenesis that is implicated in tumor progression.Dvl2-dependent activation of Daam1 and RhoA regulates Wnt5a-induced breast cancer cell migration.Hyaluronan inhibits postchemotherapy tumor regrowth in a colon carcinoma xenograft model.Overexpression of CD44 accompanies acquired tamoxifen resistance in MCF7 cells and augments their sensitivity to the stromal factors, heregulin and hyaluronan.Cancer cell glycocalyx mediates mechanotransduction and flow-regulated invasionThe anti-migratory effects of FKBPL and its peptide derivative, AD-01: regulation of CD44 and the cytoskeletal pathway.FKBPL and peptide derivatives: novel biological agents that inhibit angiogenesis by a CD44-dependent mechanism.The influence of astragalus polysaccharide and β-elemene on LX-2 cell growth, apoptosis and activation.TLR3 correlated with cervical lymph node metastasis in patients with papillary thyroid cancer.Chemotherapy-induced hyaluronan production: a novel chemoresistance mechanism in ovarian cancer.TIMP-1 deficiency subverts cell-cycle dynamics in murine long-term HSCs.
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P2860
Hyaluronan-mediated CD44 activation of RhoGTPase signaling and cytoskeleton function promotes tumor progression.
description
article científic
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article scientifique
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articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 26 March 2008
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Hyaluronan-mediated CD44 activ ...... on promotes tumor progression.
@en
Hyaluronan-mediated CD44 activ ...... on promotes tumor progression.
@nl
type
label
Hyaluronan-mediated CD44 activ ...... on promotes tumor progression.
@en
Hyaluronan-mediated CD44 activ ...... on promotes tumor progression.
@nl
prefLabel
Hyaluronan-mediated CD44 activ ...... on promotes tumor progression.
@en
Hyaluronan-mediated CD44 activ ...... on promotes tumor progression.
@nl
P2860
P1476
Hyaluronan-mediated CD44 activ ...... on promotes tumor progression.
@en
P2093
Lilly Y W Bourguignon
P2860
P304
P356
10.1016/J.SEMCANCER.2008.03.007
P577
2008-03-26T00:00:00Z