The growth factor progranulin attenuates neuronal injury induced by cerebral ischemia-reperfusion through the suppression of neutrophil recruitment - Wikidata - awgldk - TriplyDB

The growth factor progranulin attenuates neuronal injury induced by cerebral ischemia-reperfusion through the suppression of neutrophil recruitment

The growth factor progranulin attenuates neuronal injury induced by cerebral ischemia-reperfusion through the suppression of neutrophil recruitment

http://www.wikidata.org/entity/Q37152489

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Progranulin directly binds to the CRD2 and CRD3 of TNFR extracellular domains The role of progranulin in diabetes and kidney disease Therapeutic and diagnostic challenges for frontotemporal dementia Growth factors for the treatment of ischemic brain injury (growth factor treatment)Fate of graft cells: what should be clarified for development of mesenchymal stem cell therapy for ischemic stroke?Progranulin deficiency causes the retinal ganglion cell loss during development.Progranulin-derived Atsttrin directly binds to TNFRSF25 (DR3) and inhibits TNF-like ligand 1A (TL1A) activity.Progranulin facilitates conversion and function of regulatory T cells under inflammatory conditions.Three TNFR-binding domains of PGRN act independently in inhibition of TNF-alpha binding and activity.The role of PGRN in musculoskeletal development and disease.Decreased progranulin levels in patients and rats with subarachnoid hemorrhage: a potential role in inhibiting inflammation by suppressing neutrophil recruitment.Progranulin promotes colorectal cancer proliferation and angiogenesis through TNFR2/Akt and ERK signaling pathways.Progranulin Reduced Neuronal Cell Death by Activation of Sortilin 1 Signaling Pathways After Subarachnoid Hemorrhage in Rats.Progranulin deficiency leads to severe inflammation, lung injury and cell death in a mouse model of endotoxic shock.Progranulin inhibits expression and release of chemokines CXCL9 and CXCL10 in a TNFR1 dependent manner Progranulin deficiency induces overactivation of WNT5A expression via TNF-α/NF-κB pathway in peripheral cells from frontotemporal dementia-linked granulin mutation carriers.Progranulin antibodies entertain a proinflammatory environment in a subgroup of patients with psoriatic arthritis.Imbalance between TNFα and progranulin contributes to memory impairment and anxiety in sleep-deprived mice.New discovery rarely runs smooth: an update on progranulin/TNFR interactions Protective action of B1R antagonist against cerebral ischemia-reperfusion injury through suppressing miR-200c expression of Microglia-derived microvesicles.The role of progranulin in arthritis.Therapeutic Strategies to Attenuate Hemorrhagic Transformation After Tissue Plasminogen Activator Treatment for Acute Ischemic Stroke Progranulin protects against osteoarthritis through interacting with TNF-α and β-Catenin signalling.Progranulin and short-term outcome in patients with acute ischaemic stroke.White Matter Injury After Subarachnoid Hemorrhage: Role of Blood-Brain Barrier Disruption and Matrix Metalloproteinase-9.The Effect of Dexmedetomidine on Oxidative Stress Response Following Cerebral Ischemia-Reperfusion in Rats and the Expression of Intracellular Adhesion Molecule-1 (ICAM-1) and S100B.Effect of Low-Dose Alcohol Consumption on Inflammation Following Transient Focal Cerebral Ischemia in Rats.Proinflammatory progranulin antibodies in inflammatory bowel diseases.Stroke-associated infection independently predicts 3-month poor functional outcome and mortality.Intranasal administration of recombinant progranulin inhibits bronchial smooth muscle hyperresponsiveness in mouse allergic asthma.A novel IL-1RA-PEP fusion protein alleviates blood-brain barrier disruption after ischemia-reperfusion in male rats.Progranulin protects against the tissue damage of acute ischaemic stroke.Progranulin increases phagocytosis by retinal pigment epithelial cells in culture.Multiple therapeutic effects of progranulin on experimental acute ischaemic stroke.Foxo4- and Stat3-dependent IL-10 production by progranulin in regulatory T cells restrains inflammatory arthritis.Lack of Evidence for a Direct Interaction of Progranulin and Tumor Necrosis Factor Receptor-1 and Tumor Necrosis Factor Receptor-2 From Cellular Binding Studies.

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The growth factor progranulin attenuates neuronal injury induced by cerebral ischemia-reperfusion through the suppression of neutrophil recruitment

http://www.wikidata.org/entity/Q37152489

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article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 23 August 2013

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

The growth factor progranulin ...... sion of neutrophil recruitment

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The growth factor progranulin ...... ion of neutrophil recruitment.

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The growth factor progranulin ...... sion of neutrophil recruitment

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The growth factor progranulin ...... ion of neutrophil recruitment.

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The growth factor progranulin ...... sion of neutrophil recruitment

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The growth factor progranulin ...... ion of neutrophil recruitment.

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1742-2094-10-105

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Journal of Neuroinflammation

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The growth factor progranulin ...... sion of neutrophil recruitment

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Hideaki Hara

http://www.w3.org/2001/XMLSchema#string

Kazuhiro Tsuruma

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Keisuke Mishiro

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Masamitsu Shimazawa

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Masanori Kashimata

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Shinichi Yoshimura

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Sou Sugitani

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Toru Iwama

http://www.w3.org/2001/XMLSchema#string

Toshinori Takagi

http://www.w3.org/2001/XMLSchema#string

Yukio Azuma

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P2860

TNF signaling inhibition in the CNS: implications for normal brain function and neurodegenerative disease

Null mutations in progranulin cause ubiquitin-positive frontotemporal dementia linked to chromosome 17q21

Mutations in progranulin cause tau-negative frontotemporal dementia linked to chromosome 17

Heart disease and stroke statistics--2012 update: a report from the American Heart Association

The immunology of stroke: from mechanisms to translation

Proteinase 3 and neutrophil elastase enhance inflammation in mice by inactivating antiinflammatory progranulin.

Cellular localization of gene expression for progranulin.

Inflammatory mechanisms in ischemic stroke: role of inflammatory cells.

The growth factor progranulin binds to TNF receptors and is therapeutic against inflammatory arthritis in mice.

Progranulin (granulin-epithelin precursor, PC-cell-derived growth factor, acrogranin) mediates tissue repair and tumorigenesis.

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1742-2094-10-105

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2013-08-23T00:00:00Z

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1051704889

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23972823

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cerebral infarction

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3765381

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