The growth factor progranulin attenuates neuronal injury induced by cerebral ischemia-reperfusion through the suppression of neutrophil recruitment
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Progranulin directly binds to the CRD2 and CRD3 of TNFR extracellular domainsThe role of progranulin in diabetes and kidney diseaseTherapeutic and diagnostic challenges for frontotemporal dementiaGrowth factors for the treatment of ischemic brain injury (growth factor treatment)Fate of graft cells: what should be clarified for development of mesenchymal stem cell therapy for ischemic stroke?Progranulin deficiency causes the retinal ganglion cell loss during development.Progranulin-derived Atsttrin directly binds to TNFRSF25 (DR3) and inhibits TNF-like ligand 1A (TL1A) activity.Progranulin facilitates conversion and function of regulatory T cells under inflammatory conditions.Three TNFR-binding domains of PGRN act independently in inhibition of TNF-alpha binding and activity.The role of PGRN in musculoskeletal development and disease.Decreased progranulin levels in patients and rats with subarachnoid hemorrhage: a potential role in inhibiting inflammation by suppressing neutrophil recruitment.Progranulin promotes colorectal cancer proliferation and angiogenesis through TNFR2/Akt and ERK signaling pathways.Progranulin Reduced Neuronal Cell Death by Activation of Sortilin 1 Signaling Pathways After Subarachnoid Hemorrhage in Rats.Progranulin deficiency leads to severe inflammation, lung injury and cell death in a mouse model of endotoxic shock.Progranulin inhibits expression and release of chemokines CXCL9 and CXCL10 in a TNFR1 dependent mannerProgranulin deficiency induces overactivation of WNT5A expression via TNF-α/NF-κB pathway in peripheral cells from frontotemporal dementia-linked granulin mutation carriers.Progranulin antibodies entertain a proinflammatory environment in a subgroup of patients with psoriatic arthritis.Imbalance between TNFα and progranulin contributes to memory impairment and anxiety in sleep-deprived mice.New discovery rarely runs smooth: an update on progranulin/TNFR interactionsProtective action of B1R antagonist against cerebral ischemia-reperfusion injury through suppressing miR-200c expression of Microglia-derived microvesicles.The role of progranulin in arthritis.Therapeutic Strategies to Attenuate Hemorrhagic Transformation After Tissue Plasminogen Activator Treatment for Acute Ischemic StrokeProgranulin protects against osteoarthritis through interacting with TNF-α and β-Catenin signalling.Progranulin and short-term outcome in patients with acute ischaemic stroke.White Matter Injury After Subarachnoid Hemorrhage: Role of Blood-Brain Barrier Disruption and Matrix Metalloproteinase-9.The Effect of Dexmedetomidine on Oxidative Stress Response Following Cerebral Ischemia-Reperfusion in Rats and the Expression of Intracellular Adhesion Molecule-1 (ICAM-1) and S100B.Effect of Low-Dose Alcohol Consumption on Inflammation Following Transient Focal Cerebral Ischemia in Rats.Proinflammatory progranulin antibodies in inflammatory bowel diseases.Stroke-associated infection independently predicts 3-month poor functional outcome and mortality.Intranasal administration of recombinant progranulin inhibits bronchial smooth muscle hyperresponsiveness in mouse allergic asthma.A novel IL-1RA-PEP fusion protein alleviates blood-brain barrier disruption after ischemia-reperfusion in male rats.Progranulin protects against the tissue damage of acute ischaemic stroke.Progranulin increases phagocytosis by retinal pigment epithelial cells in culture.Multiple therapeutic effects of progranulin on experimental acute ischaemic stroke.Foxo4- and Stat3-dependent IL-10 production by progranulin in regulatory T cells restrains inflammatory arthritis.Lack of Evidence for a Direct Interaction of Progranulin and Tumor Necrosis Factor Receptor-1 and Tumor Necrosis Factor Receptor-2 From Cellular Binding Studies.
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P2860
The growth factor progranulin attenuates neuronal injury induced by cerebral ischemia-reperfusion through the suppression of neutrophil recruitment
description
article científic
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article scientifique
@fr
articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 23 August 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
The growth factor progranulin ...... sion of neutrophil recruitment
@en
The growth factor progranulin ...... ion of neutrophil recruitment.
@nl
type
label
The growth factor progranulin ...... sion of neutrophil recruitment
@en
The growth factor progranulin ...... ion of neutrophil recruitment.
@nl
prefLabel
The growth factor progranulin ...... sion of neutrophil recruitment
@en
The growth factor progranulin ...... ion of neutrophil recruitment.
@nl
P2093
P2860
P356
P1476
The growth factor progranulin ...... sion of neutrophil recruitment
@en
P2093
Hideaki Hara
Kazuhiro Tsuruma
Keisuke Mishiro
Masamitsu Shimazawa
Masanori Kashimata
Shinichi Yoshimura
Sou Sugitani
Toru Iwama
Toshinori Takagi
Yukio Azuma
P2860
P2888
P356
10.1186/1742-2094-10-105
P577
2013-08-23T00:00:00Z
P5875
P6179
1051704889