TW-37, a small-molecule inhibitor of Bcl-2, inhibits cell growth and invasion in pancreatic cancer. - Wikidata - awgldk - TriplyDB

TW-37, a small-molecule inhibitor of Bcl-2, inhibits cell growth and invasion in pancreatic cancer.

TW-37, a small-molecule inhibitor of Bcl-2, inhibits cell growth and invasion in pancreatic cancer.

http://www.wikidata.org/entity/Q37154117

about

Baicalein, a component of Scutellaria baicalensis, induces apoptosis by Mcl-1 down-regulation in human pancreatic cancer cells Targeting Cell Survival Proteins for Cancer Cell Death Targeting BCL2-Proteins for the Treatment of Solid Tumours Targeting the Bcl-2 family for cancer therapy Selectivity by small-molecule inhibitors of protein interactions can be driven by protein surface fluctuations Emerging Bcl-2 inhibitors for the treatment of cancer.New potential anti-cancer agents synergize with bortezomib and ABT-737 against prostate cancer.Metronomic small molecule inhibitor of Bcl-2 (TW-37) is antiangiogenic and potentiates the antitumor effect of ionizing radiation Regulated cell death pathways: new twists in modulation of BCL2 family function Small molecule inhibitors of bcl-2 family proteins for pancreatic cancer therapy Inhibitors of the anti-apoptotic Bcl-2 proteins: a patent review.Non-peptidic small molecule inhibitors against Bcl-2 for cancer therapy.Corticotropin Releasing Factor promotes breast cancer cell motility and invasiveness.TW-37, a small-molecule inhibitor of Bcl-2, inhibits cell growth and induces apoptosis in pancreatic cancer: involvement of Notch-1 signaling pathway.Apoptosis pathways and their therapeutic exploitation in pancreatic cancer.Mimicking the BH3 domain to kill cancer cells PAR-4 as a possible new target for pancreatic cancer therapy.Small-molecule inhibitors reveal a new function for Bcl-2 as a proangiogenic signaling molecule.Angiogenesis inhibitors in cancer therapy: mechanistic perspective on classification and treatment rationales.Targeting cancer cell mitochondria as a therapeutic approach: recent updates.DRP-1 is required for BH3 mimetic-mediated mitochondrial fragmentation and apoptosis.MiR-148a regulates the growth and apoptosis in pancreatic cancer by targeting CCKBR and Bcl-2.TW-37, a small-molecule inhibitor of Bcl-2, mediates S-phase cell cycle arrest and suppresses head and neck tumor angiogenesis.Evaluation and critical assessment of putative MCL-1 inhibitors.Targeting apoptosis signaling in pancreatic cancer The preclinical analysis of TW-37 as a potential anti-colorectal cancer cell agent.Apoptosis sensitizers enhance cytotoxicity in hepatoblastoma cells.Discovery of Mcl-1 inhibitors from integrated high throughput and virtual screening

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TW-37, a small-molecule inhibitor of Bcl-2, inhibits cell growth and invasion in pancreatic cancer.

http://www.wikidata.org/entity/Q37154117

description

article científic

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article scientifique

@fr

articolo scientifico

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artigo científico

@pt

bilimsel makale

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scientific article published on August 2008

@en

vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

TW-37, a small-molecule inhibi ...... invasion in pancreatic cancer.

@en

TW-37, a small-molecule inhibi ...... invasion in pancreatic cancer.

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type

label

TW-37, a small-molecule inhibi ...... invasion in pancreatic cancer.

@en

TW-37, a small-molecule inhibi ...... invasion in pancreatic cancer.

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prefLabel

TW-37, a small-molecule inhibi ...... invasion in pancreatic cancer.

@en

TW-37, a small-molecule inhibi ...... invasion in pancreatic cancer.

@nl

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International Journal of Cancer

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TW-37, a small-molecule inhibi ...... invasion in pancreatic cancer.

@en

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Amro Aboukameel

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Dejuan Kong

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Fazlul H Sarkar

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Guoping Wang

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Mussop Mohammad

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Ramzi M Mohammad

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Sanjeev Banerjee

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Shaomeng Wang

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Wen Song

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Zhiwei Wang

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P2860

The Bcl-2 apoptotic switch in cancer development and therapy

Nonsteroidal anti-inflammatory agents differ in their ability to suppress NF-kappaB activation, inhibition of expression of cyclooxygenase-2 and cyclin D1, and abrogation of tumor cell proliferation

Down-regulation of Forkhead Box M1 transcription factor leads to the inhibition of invasion and angiogenesis of pancreatic cancer cells

Cancer statistics, 2007

Matrix metalloproteinases: molecular aspects of their roles in tumour invasion and metastasis.

Molecular prognostic markers in pancreatic cancer: a systematic review.

Matrix metalloproteinase activity and osteoclasts in experimental prostate cancer bone metastasis tissue.

NF-kappaB in pancreatic cancer.

Pharmacogenetics of anticancer drug sensitivity in pancreatic cancer.

Nuclear factor-kappaB in development, prevention, and therapy of cancer.

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958-966

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scholarly article

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10.1002/IJC.23610

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4

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123

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Fazlul H. Sarkar

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2008-08-01T00:00:00Z

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5328690

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18528859

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3766317

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