TW-37, a small-molecule inhibitor of Bcl-2, inhibits cell growth and invasion in pancreatic cancer.
about
Baicalein, a component of Scutellaria baicalensis, induces apoptosis by Mcl-1 down-regulation in human pancreatic cancer cellsTargeting Cell Survival Proteins for Cancer Cell DeathTargeting BCL2-Proteins for the Treatment of Solid TumoursTargeting the Bcl-2 family for cancer therapySelectivity by small-molecule inhibitors of protein interactions can be driven by protein surface fluctuationsEmerging Bcl-2 inhibitors for the treatment of cancer.New potential anti-cancer agents synergize with bortezomib and ABT-737 against prostate cancer.Metronomic small molecule inhibitor of Bcl-2 (TW-37) is antiangiogenic and potentiates the antitumor effect of ionizing radiationRegulated cell death pathways: new twists in modulation of BCL2 family functionSmall molecule inhibitors of bcl-2 family proteins for pancreatic cancer therapyInhibitors of the anti-apoptotic Bcl-2 proteins: a patent review.Non-peptidic small molecule inhibitors against Bcl-2 for cancer therapy.Corticotropin Releasing Factor promotes breast cancer cell motility and invasiveness.TW-37, a small-molecule inhibitor of Bcl-2, inhibits cell growth and induces apoptosis in pancreatic cancer: involvement of Notch-1 signaling pathway.Apoptosis pathways and their therapeutic exploitation in pancreatic cancer.Mimicking the BH3 domain to kill cancer cellsPAR-4 as a possible new target for pancreatic cancer therapy.Small-molecule inhibitors reveal a new function for Bcl-2 as a proangiogenic signaling molecule.Angiogenesis inhibitors in cancer therapy: mechanistic perspective on classification and treatment rationales.Targeting cancer cell mitochondria as a therapeutic approach: recent updates.DRP-1 is required for BH3 mimetic-mediated mitochondrial fragmentation and apoptosis.MiR-148a regulates the growth and apoptosis in pancreatic cancer by targeting CCKBR and Bcl-2.TW-37, a small-molecule inhibitor of Bcl-2, mediates S-phase cell cycle arrest and suppresses head and neck tumor angiogenesis.Evaluation and critical assessment of putative MCL-1 inhibitors.Targeting apoptosis signaling in pancreatic cancerThe preclinical analysis of TW-37 as a potential anti-colorectal cancer cell agent.Apoptosis sensitizers enhance cytotoxicity in hepatoblastoma cells.Discovery of Mcl-1 inhibitors from integrated high throughput and virtual screening
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TW-37, a small-molecule inhibitor of Bcl-2, inhibits cell growth and invasion in pancreatic cancer.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on August 2008
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
TW-37, a small-molecule inhibi ...... invasion in pancreatic cancer.
@en
TW-37, a small-molecule inhibi ...... invasion in pancreatic cancer.
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type
label
TW-37, a small-molecule inhibi ...... invasion in pancreatic cancer.
@en
TW-37, a small-molecule inhibi ...... invasion in pancreatic cancer.
@nl
prefLabel
TW-37, a small-molecule inhibi ...... invasion in pancreatic cancer.
@en
TW-37, a small-molecule inhibi ...... invasion in pancreatic cancer.
@nl
P2093
P2860
P356
P1476
TW-37, a small-molecule inhibi ...... invasion in pancreatic cancer.
@en
P2093
Amro Aboukameel
Dejuan Kong
Fazlul H Sarkar
Guoping Wang
Mussop Mohammad
Ramzi M Mohammad
Sanjeev Banerjee
Shaomeng Wang
Zhiwei Wang
P2860
P304
P356
10.1002/IJC.23610
P577
2008-08-01T00:00:00Z