Targeting the Bcl-2 family for cancer therapy - Wikidata - awgldk - TriplyDB

Targeting the Bcl-2 family for cancer therapy

Targeting the Bcl-2 family for cancer therapy

http://www.wikidata.org/entity/Q26866936

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Targeting Cell Survival Proteins for Cancer Cell Death Potential of apoptotic pathway-targeted cancer therapeutic research: Where do we stand?Targeting the apoptosis pathway in hematologic malignancies Alternative Treatments For Melanoma: Targeting BCL-2 Family Members to De-Bulk and Kill Cancer Stem Cells Autophagy-Induced Apoptosis in Lung Cancer Cells by a Novel Digitoxin Analog BcL-xL conformational changes upon fragment binding revealed by NMR Direct Activation of Bax Protein for Cancer Therapy Molecular Role of EGFR-MAPK Pathway in Patchouli Alcohol-Induced Apoptosis and Cell Cycle Arrest on A549 Cells In Vitro and In Vivo.Nanoencapsulation of ABT-737 and camptothecin enhances their clinical potential through synergistic antitumor effects and reduction of systemic toxicity.miR-365 induces hepatocellular carcinoma cell apoptosis through targeting Bcl-2.Development and antitumor activity of a BCL-2 targeted single-stranded DNA oligonucleotide.Members of the microRNA-200 family are promising therapeutic targets in cancer.Effect of ERβ-regulated ERK1/2 signaling on biological behaviors of prostate cancer cells.Inhibition of protein phosphatase 2A (PP2A) prevents Mcl-1 protein dephosphorylation at the Thr-163/Ser-159 phosphodegron, dramatically reducing expression in Mcl-1-amplified lymphoma cells.Prognostic and therapeutic impact of RPN2-mediated tumor malignancy in non-small-cell lung cancer.Intracellular delivery system for antibody-Peptide drug conjugates Hematologic malignancies: newer strategies to counter the BCL-2 protein.Ethyl acetate extract of Hypericum japonicum induces apoptosis via the mitochondria-dependent pathway in vivo and in vitro Targeting Bcl-2 stability to sensitize cells harboring oncogenic ras Crosstalk between Bcl-2 family and Ras family small GTPases: potential cell fate regulation?The tissue dependent interactions between p53 and Bcl-2 in vivo.Bit1 knockdown contributes to growth suppression as well as the decreases of migration and invasion abilities in esophageal squamous cell carcinoma via suppressing FAK-paxillin pathway.BH4 domain of Bcl-2 as a novel target for cancer therapy Ablation of MCL1 expression by virally induced microRNA-29 reverses chemoresistance in human osteosarcomas.Quercetin-induced apoptosis of HT-29 colon cancer cells via inhibition of the Akt-CSN6-Myc signaling axis.Celastrus orbiculatus extract triggers apoptosis and autophagy via PI3K/Akt/mTOR inhibition in human colorectal cancer cells Mcl-1 mediates TWEAK/Fn14-induced non-small cell lung cancer survival and therapeutic response.Programming cancer cells for high expression levels of Mcl1.Targeting BCL2 family in human myeloid dendritic cells: a challenge to cure diseases with chronic inflammations associated with bone loss.G-quadruplex structures in the human genome as novel therapeutic targets.The regulation and biosynthesis of antimycins Nanoscale particulate systems for multidrug delivery: towards improved combination chemotherapy.Non-BRAF targeted therapies for melanoma: protein kinase inhibitors in Phase II clinical trials.Apoptosis inducers in chronic lymphocytic leukemia.An enhanced functional interrogation/manipulation of intracellular signaling pathways with the peptide 'stapling' technology.New dimension in therapeutic targeting of BCL-2 family proteins.Aruncin B: Synthetic Studies, Structural Reassignment and Biological Evaluation.Molecular mechanisms and clinical implications of miRNAs in drug resistance of esophageal cancer.Combined Treatment with Stattic and Docetaxel Alters the Bax/Bcl-2 Gene Expression Ratio in Human Prostate Cancer Cells Addressing intra-tumoral heterogeneity and therapy resistance.

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P2860

Targeting the Bcl-2 family for cancer therapy

http://www.wikidata.org/entity/Q26866936

description

2013 nî lūn-bûn

@nan

2013 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

2013 թվականի հունվարին հրատարակված գիտական հոդված

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2013年の論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

@zh-tw

2013年论文

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name

Targeting the Bcl-2 family for cancer therapy

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Targeting the Bcl-2 family for cancer therapy

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Targeting the Bcl-2 family for cancer therapy

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type

label

Targeting the Bcl-2 family for cancer therapy

@ast

Targeting the Bcl-2 family for cancer therapy

@en

Targeting the Bcl-2 family for cancer therapy

@nl

prefLabel

Targeting the Bcl-2 family for cancer therapy

@ast

Targeting the Bcl-2 family for cancer therapy

@en

Targeting the Bcl-2 family for cancer therapy

@nl

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14728222.2013.733001

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Expert Opinion on Therapeutic Targets

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Targeting the Bcl-2 family for cancer therapy

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P2093

Bridget A Quinn

http://www.w3.org/2001/XMLSchema#string

Devanand Sarkar

http://www.w3.org/2001/XMLSchema#string

John C Reed

http://www.w3.org/2001/XMLSchema#string

Luni Emdad

http://www.w3.org/2001/XMLSchema#string

Paul B Fisher

http://www.w3.org/2001/XMLSchema#string

Santanu Dasgupta

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Shibu Thomas

http://www.w3.org/2001/XMLSchema#string

Swadesh K Das

http://www.w3.org/2001/XMLSchema#string

Xiang-Yang Wang

http://www.w3.org/2001/XMLSchema#string

P2860

PUMA, a novel proapoptotic gene, is induced by p53

Apoptosis initiated when BH3 ligands engage multiple Bcl-2 homologs, not Bax or Bak

Functional and physical interaction between Bcl-X(L) and a BH3-like domain in Beclin-1

Mule/ARF-BP1, a BH3-only E3 ubiquitin ligase, catalyzes the polyubiquitination of Mcl-1 and regulates apoptosis

bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death

Evidence that BCL-2 represses apoptosis by regulating endoplasmic reticulum-associated Ca2+ fluxes

A short Nur77-derived peptide converts Bcl-2 from a protector to a killer

miR-15 and miR-16 induce apoptosis by targeting BCL2

Targeting Mcl-1 for the therapy of cancer

Crystal structure of the Bcl-XL-Beclin 1 peptide complex: Beclin 1 is a novel BH3-only protein

P304

61-75

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scholarly article

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341976

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10.1517/14728222.2013.733001

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1

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17

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Maurizio Pellecchia

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2013-01-01T00:00:00Z

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23173842

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3955095

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