The transcription factor snail mediates epithelial to mesenchymal transitions by repression of estrogen receptor-alpha.
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HSulf-1 modulates FGF2- and hypoxia-mediated migration and invasion of breast cancer cellsTumor-specific expression of microRNA-26a suppresses human hepatocellular carcinoma growth via cyclin-dependent and -independent pathwaysRole of EMT in Metastasis and Therapy ResistanceLinking epithelial-to-mesenchymal-transition and epigenetic modificationsObesity, metabolic dysregulation, and cancer: a growing concern and an inflammatory (and microenvironmental) issueCentral role of Snail1 in the regulation of EMT and resistance in cancer: a target for therapeutic interventionDeconvoluting the obesity and breast cancer link: secretome, soil and seed interactionsEnvironmental immune disruptors, inflammation and cancer riskDisruptive environmental chemicals and cellular mechanisms that confer resistance to cell deathThe transcription factors Snail and Slug activate the transforming growth factor-beta signaling pathway in breast cancerSlug controls stem/progenitor cell growth dynamics during mammary gland morphogenesisGene expression profiling supports the hypothesis that human ovarian surface epithelia are multipotent and capable of serving as ovarian cancer initiating cells.Aurora-A mitotic kinase induces endocrine resistance through down-regulation of ERα expression in initially ERα+ breast cancer cells.Loss of estrogen receptor 1 enhances cervical cancer invasion.Role of estrogen receptors and Src signaling in mechanisms of bone metastasis by estrogen receptor positive breast cancers.Yin yang 1 regulates the expression of snail through a distal enhancer.Mode of action of the retrogene product SNAI1P, a SNAIL homolog, in human breast cancer cellsProteasome inhibition represses ERalpha gene expression in ER+ cells: a new link between proteasome activity and estrogen signaling in breast cancerMechanisms of the epithelial-mesenchymal transition by TGF-betaProteomic and transcriptomic profiling reveals a link between the PI3K pathway and lower estrogen-receptor (ER) levels and activity in ER+ breast cancer.Snail family regulation and epithelial mesenchymal transitions in breast cancer progressionTNFalpha up-regulates SLUG via the NF-kappaB/HIF1alpha axis, which imparts breast cancer cells with a stem cell-like phenotype.Loss of breast epithelial marker hCLCA2 promotes epithelial-to-mesenchymal transition and indicates higher risk of metastasisProlonged drug selection of breast cancer cells and enrichment of cancer stem cell characteristicsDeregulation of the Pit-1 transcription factor in human breast cancer cells promotes tumor growth and metastasisCorrelation between Slug transcription factor and miR-221 in MDA-MB-231 breast cancer cells.Role of MTA1 in cancer progression and metastasisLobular breast cancers lack the inverse relationship between ER/PR status and cell growth rate characteristic of ductal cancers in two independent patient cohorts: implications for tumor biology and adjuvant therapyDynamic transcription factor networks in epithelial-mesenchymal transition in breast cancer models.Chromatin remodelling and actin organisation.Transforming growth factor-β-induced epithelial-mesenchymal transition facilitates epidermal growth factor-dependent breast cancer progressionObesity, independent of p53 gene dosage, promotes mammary tumor progression and upregulates the p53 regulator microRNA-504.Proteomic analysis of coregulators bound to ERα on DNA and nucleosomes reveals coregulator dynamics.The proteasome inhibitor bortezomib induces an inhibitory chromatin environment at a distal enhancer of the estrogen receptor-α gene.CCN5, a novel transcriptional repressor of the transforming growth factor β signaling pathwayCytokine receptor CXCR4 mediates estrogen-independent tumorigenesis, metastasis, and resistance to endocrine therapy in human breast cancer.Hypoxia negatively regulates heparan sulfatase 2 expression in renal cancer cell lines.Chemotherapeutic Targeting of the Transforming Growth Factor-β Pathway in Breast Cancers.FBXO11 promotes ubiquitination of the Snail family of transcription factors in cancer progression and epidermal development.RNA polymerase II pausing can be retained or acquired during activation of genes involved in the epithelial to mesenchymal transition.
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The transcription factor snail mediates epithelial to mesenchymal transitions by repression of estrogen receptor-alpha.
description
article científic
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article scientifique
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articolo scientifico
@it
artigo científico
@pt
bilimsel makale
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scientific article published on 30 August 2007
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
The transcription factor snail ...... on of estrogen receptor-alpha.
@en
The transcription factor snail ...... on of estrogen receptor-alpha.
@nl
type
label
The transcription factor snail ...... on of estrogen receptor-alpha.
@en
The transcription factor snail ...... on of estrogen receptor-alpha.
@nl
prefLabel
The transcription factor snail ...... on of estrogen receptor-alpha.
@en
The transcription factor snail ...... on of estrogen receptor-alpha.
@nl
P2093
P2860
P356
P1476
The transcription factor snail ...... on of estrogen receptor-alpha.
@en
P2093
Archana Dhasarathy
Masahiro Kajita
Paul A Wade
P2860
P304
P356
10.1210/ME.2007-0293
P577
2007-08-30T00:00:00Z