MEK inhibition affects STAT3 signaling and invasion in human melanoma cell lines
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Multiple Molecular Pathways in Melanomagenesis: Characterization of Therapeutic TargetsCADM1 inhibits squamous cell carcinoma progression by reducing STAT3 activity.Enhancing the evaluation of PI3K inhibitors through 3D melanoma models.The MAPK pathway as an apoptosis enhancer in melanoma.MicroRNA-17 inhibits tumor growth by stimulating T-cell mediated host immune response.Phosphoproteomic analysis of basal and therapy-induced adaptive signaling networks in BRAF and NRAS mutant melanoma.Multifunctional bioscaffolds for 3D culture of melanoma cells reveal increased MMP activity and migration with BRAF kinase inhibition.MIG6 Is MEK Regulated and Affects EGF-Induced Migration in Mutant NRAS Melanoma.Activity-Based Proteomics Reveals Heterogeneous Kinome and ATP-Binding Proteome Responses to MEK Inhibition in KRAS Mutant Lung Cancer.PIM kinases as therapeutic targets against advanced melanoma.Towards combinatorial targeted therapy in melanoma: from pre-clinical evidence to clinical application (review).Effect of Selumetinib and MK-2206 vs Oxaliplatin and Fluorouracil in Patients With Metastatic Pancreatic Cancer After Prior Therapy: SWOG S1115 Study Randomized Clinical Trial.The current management of brain metastasis in melanoma: a focus on riluzole.JAK1/STAT3 activation through a proinflammatory cytokine pathway leads to resistance to molecularly targeted therapy in non-small cell lung cancer.A Nexus Consisting of Beta-Catenin and Stat3 Attenuates BRAF Inhibitor Efficacy and Mediates Acquired Resistance to Vemurafenib.Crosstalk signaling in targeted melanoma therapy.ERK/MAPK Signaling Drives Overexpression of the Rac-GEF, PREX1, in BRAF- and NRAS-Mutant Melanoma.STAT3-mediated SMAD3 activation underlies Oncostatin M-induced Senescence.Belinostat exerts antitumor cytotoxicity through the ubiquitin-proteasome pathway in lung squamous cell carcinomaAbl kinase regulation by BRAF/ERK and cooperation with Akt in melanoma.Anti-chondroitin sulfate proteoglycan 4-specific antibodies modify the effects of vemurafenib on melanoma cells differentially in normoxia and hypoxia.Regulation of viability, differentiation and death of human melanoma cells carrying neural stem cell biomarkers: a possibility for neural trans-differentiation.Real-time cell cycle imaging during melanoma growth, invasion, and drug response.Potential therapeutic targets of epithelial-mesenchymal transition in melanoma.Targeting invasive properties of melanoma cells.Context-dependent miR-204 and miR-211 affect the biological properties of amelanotic and melanotic melanoma cells.Targeting Notch enhances the efficacy of ERK inhibitors in BRAF-V600E melanoma.Simultaneous blocking of IL-6 and IL-8 is sufficient to fully inhibit CAF-induced human melanoma cell invasiveness.The UPs and DOWNs of MITF in melanoma resistance.Biochemical Properties of a Decoy Oligodeoxynucleotide Inhibitor of STAT3 Transcription Factor.
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MEK inhibition affects STAT3 signaling and invasion in human melanoma cell lines
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 29 April 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
MEK inhibition affects STAT3 signaling and invasion in human melanoma cell lines
@en
MEK inhibition affects STAT3 signaling and invasion in human melanoma cell lines.
@nl
type
label
MEK inhibition affects STAT3 signaling and invasion in human melanoma cell lines
@en
MEK inhibition affects STAT3 signaling and invasion in human melanoma cell lines.
@nl
prefLabel
MEK inhibition affects STAT3 signaling and invasion in human melanoma cell lines
@en
MEK inhibition affects STAT3 signaling and invasion in human melanoma cell lines.
@nl
P2093
P2860
P356
P1433
P1476
MEK inhibition affects STAT3 signaling and invasion in human melanoma cell lines
@en
P2093
J Villanueva
P A Gimotty
P2860
P2888
P304
P356
10.1038/ONC.2013.131
P407
P577
2013-04-29T00:00:00Z