Spatial and temporal coordination of mitosis by Ran GTPase.
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Impairment of glioma stem cell survival and growth by a novel inhibitor for Survivin-Ran protein complexProteomics identification of nuclear Ran GTPase as an inhibitor of human VRK1 and VRK2 (vaccinia-related kinase) activitiesProtein phosphatase 6 regulates mitotic spindle formation by controlling the T-loop phosphorylation state of Aurora A bound to its activator TPX2Plk1-dependent recruitment of gamma-tubulin complexes to mitotic centrosomes involves multiple PCM componentsKinetochore-microtubule interactions: steps towards bi-orientationDesign of versatile biochemical switches that respond to amplitude, duration, and spatial cuesOn the Archaeal Origins of Eukaryotes and the Challenges of Inferring Phenotype from GenotypeNon-centrosomal TPX2-Dependent Regulation of the Aurora A Kinase: Functional Implications for Healthy and Pathological Cell DivisionMechanisms of Nuclear Export in Cancer and Resistance to ChemotherapyThe RanGTP Pathway: From Nucleo-Cytoplasmic Transport to Spindle Assembly and BeyondSubversion of Cell-Autonomous Immunity and Cell Migration by Legionella pneumophila EffectorsThe 3' to 5' Exoribonuclease DIS3: From Structure and Mechanisms to Biological Functions and Role in Human DiseasePhysical breakdown of the nuclear envelope is not necessary for breaking its barrier functionDeciphering how the chromatin factor RCC1 recognizes the nucleosome: the importance of individuals in the scientific discovery processChromatin binding of RCC1 during mitosis is important for its nuclear localization in interphaseTPX2 phosphorylation maintains metaphase spindle length by regulating microtubule flux.The Ran-GTP gradient spatially regulates XCTK2 in the spindle.RAN nucleo-cytoplasmic transport and mitotic spindle assembly partners XPO7 and TPX2 are new prognostic biomarkers in serous epithelial ovarian cancerHuman mutations affect the epigenetic/bookmarking function of HNF1BActivation of Ran GTPase by a Legionella effector promotes microtubule polymerization, pathogen vacuole motility and infectionNovel Binding of the Mitotic Regulator TPX2 (Target Protein for Xenopus Kinesin-like Protein 2) to Importin-αStructure of RCC1 chromatin factor bound to the nucleosome core particleLocalization of retinitis pigmentosa 2 to cilia is regulated by Importin beta2.RHAMM promotes interphase microtubule instability and mitotic spindle integrity through MEK1/ERK1/2 activityA Group of ent-Kaurane Diterpenoids Inhibit Hedgehog Signaling and Induce Cilia ElongationVasopressin V1a receptor is required for nucleocytoplasmic transport of mineralocorticoid receptorStrategies for crystallizing a chromatin protein in complex with the nucleosome core particle.Chromosomal gain promotes formation of a steep RanGTP gradient that drives mitosis in aneuploid cells.Nuclear-cytoplasmic trafficking of NTF2, the nuclear import receptor for the RanGTPase, is subjected to regulation.Activation of the Ran GTPase is subject to growth factor regulation and can give rise to cellular transformation.The methylated N-terminal tail of RCC1 is required for stabilisation of its interaction with chromatin by Ran in live cells.Self-organization of intracellular gradients during mitosis.Lte1, Cdc14 and MEN-controlled Cdk inactivation in yeast coordinate rDNA decompaction with late telophase progression.Dynamic release of nuclear RanGTP triggers TPX2-dependent microtubule assembly during the apoptotic execution phase.Dynamic localisation of Ran GTPase during the cell cycle.Reaction-diffusion systems in intracellular molecular transport and controlcellPACK: a virtual mesoscope to model and visualize structural systems biology.Triggering signaling pathways using F-actin self-organization.Ran-dependent TPX2 activation promotes acentrosomal microtubule nucleation in neurons.Samp1, a RanGTP binding transmembrane protein in the inner nuclear membrane.
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Spatial and temporal coordination of mitosis by Ran GTPase.
description
article científic
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article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
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scientific article published on 14 May 2008
@en
vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Spatial and temporal coordination of mitosis by Ran GTPase.
@en
Spatial and temporal coordination of mitosis by Ran GTPase.
@nl
type
label
Spatial and temporal coordination of mitosis by Ran GTPase.
@en
Spatial and temporal coordination of mitosis by Ran GTPase.
@nl
prefLabel
Spatial and temporal coordination of mitosis by Ran GTPase.
@en
Spatial and temporal coordination of mitosis by Ran GTPase.
@nl
P2860
P356
P1476
Spatial and temporal coordination of mitosis by Ran GTPase.
@en
P2093
Chuanmao Zhang
Paul R Clarke
P2860
P2888
P304
P356
10.1038/NRM2410
P577
2008-05-14T00:00:00Z
P6179
1015207461