A functional homologue of the RNA1 gene product in Schizosaccharomyces pombe: purification, biochemical characterization, and identification of a leucine-rich repeat motif.
about
A novel ubiquitin-like modification modulates the partitioning of the Ran-GTPase-activating protein RanGAP1 between the cytosol and the nuclear pore complexHuman RanGTPase-activating protein RanGAP1 is a homologue of yeast Rna1p involved in mRNA processing and transportCo-activation of RanGTPase and inhibition of GTP dissociation by Ran-GTP binding protein RanBP1Importin beta, transportin, RanBP5 and RanBP7 mediate nuclear import of ribosomal proteins in mammalian cellsDominant-negative mutants of importin-beta block multiple pathways of import and export through the nuclear pore complexNTF2 mediates nuclear import of Ran.Monoclonal antibodies to NTF2 inhibit nuclear protein import by preventing nuclear translocation of the GTPase RanA domain unique to plant RanGAP is responsible for its targeting to the plant nuclear rimDis3, implicated in mitotic control, binds directly to Ran and enhances the GEF activity of RCC1Identification of different roles for RanGDP and RanGTP in nuclear protein importSeparate domains of the Ran GTPase interact with different factors to regulate nuclear protein import and RNA processingMolecular characterization of the SUMO-1 modification of RanGAP1 and its role in nuclear envelope associationRan-dependent nuclear export mediators: a structural perspectiveYrb2p is a nuclear protein that interacts with Prp20p, a yeast Rcc1 homologue.Mutants in a yeast Ran binding protein are defective in nuclear transport.Yrb2p, a Nup2p-related yeast protein, has a functional overlap with Rna1p, a yeast Ran-GTPase-activating protein.Nucleus-associated pools of Rna1p, the Saccharomyces cerevisiae Ran/TC4 GTPse activating protein involved in nucleus/cytosol transit.The NTF2 gene encodes an essential, highly conserved protein that functions in nuclear transport in vivo.nup1 mutants exhibit pleiotropic defects in nuclear pore complex function.Rna1p, a Ran/TC4 GTPase activating protein, is required for nuclear import.Preferential modification of nuclear proteins by a novel ubiquitin-like moleculeRNA1 encodes a GTPase-activating protein specific for Gsp1p, the Ran/TC4 homologue of Saccharomyces cerevisiaeModification of Ran GTPase-activating protein by the small ubiquitin-related modifier SUMO-1 requires Ubc9, an E2-type ubiquitin-conjugating enzyme homologueThe asymmetric distribution of the constituents of the Ran system is essential for transport into and out of the nucleusGoing green: plants' alternative way to position the Ran gradient.Nuclear RNA export pathways.Transport of macromolecules between the nucleus and the cytoplasmmRNA transport in yeast: time to reinvestigate the functions of the nucleolus.Isolation and characterization of fission yeast sns mutants defective at the mitosis-to-interphase transition.The fission yeast ran GTPase is required for microtubule integrity.Perturbations in the spi1p GTPase cycle of Schizosaccharomyces pombe through its GTPase-activating protein and guanine nucleotide exchange factor components result in similar phenotypic consequences.Nucleocytoplasmic transport of macromoleculesGTP hydrolysis by Ran occurs at the nuclear pore complex in an early step of protein importSpatial and temporal coordination of mitosis by Ran GTPase.A RanGAP protein physically interacts with the NB-LRR protein Rx, and is required for Rx-mediated viral resistance.A monoclonal antibody to the COOH-terminal acidic portion of Ran inhibits both the recycling of Ran and nuclear protein import in living cellsCharacterization of a fission yeast SUMO-1 homologue, pmt3p, required for multiple nuclear events, including the control of telomere length and chromosome segregation.Yeast N1e3p/Nup170p is required for normal stoichiometry of FG nucleoporins within the nuclear pore complex.Characterization of the nuclear protein import mechanism using Ran mutants with altered nucleotide binding specificitiesThe small nuclear GTPase Ran: how much does it run?
P2860
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P2860
A functional homologue of the RNA1 gene product in Schizosaccharomyces pombe: purification, biochemical characterization, and identification of a leucine-rich repeat motif.
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
1993年论文
@zh
1993年论文
@zh-cn
name
A functional homologue of the ...... f a leucine-rich repeat motif.
@en
type
label
A functional homologue of the ...... f a leucine-rich repeat motif.
@en
prefLabel
A functional homologue of the ...... f a leucine-rich repeat motif.
@en
P2093
P2860
P356
P1476
A functional homologue of the ...... f a leucine-rich repeat motif.
@en
P2093
P2860
P304
P356
10.1091/MBC.4.6.569
P577
1993-06-01T00:00:00Z