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MYC is a metastasis gene for non-small-cell lung cancerThe tumor suppressor gene TUSC2 (FUS1) sensitizes NSCLC to the AKT inhibitor MK2206 in LKB1-dependent mannerNo association between promoter polymorphism of STK11 gene and lung cancer risk in the Korean population.LKB1 tumor suppressor protein regulates actin filament assembly through Rho and its exchange factor Dbl independently of kinase activity.Protein kinase LKB1 promotes RAB7-mediated neuropilin-1 degradation to inhibit angiogenesis.Role of LKB1-CRTC1 on glycosylated COX-2 and response to COX-2 inhibition in lung cancer.Lkb1 loss promotes tumor progression of BRAF(V600E)-induced lung adenomasThe LKB1 tumor suppressor as a biomarker in mouse and human tissues.LKB1 gene inactivation does not sensitize non-small cell lung cancer cells to mTOR inhibitors in vitroGenetic and biochemical alterations in non-small cell lung cancer.Differential association of STK11 and TP53 with KRAS mutation-associated gene expression, proliferation and immune surveillance in lung adenocarcinoma.LKB1/STK11 inactivation leads to expansion of a prometastatic tumor subpopulation in melanomaA Sensitive NanoString-Based Assay to Score STK11 (LKB1) Pathway Disruption in Lung Adenocarcinoma.Aberrant NRP-1 expression serves as predicator of metastatic endometrial and lung cancers.LKB1 controls human bronchial epithelial morphogenesis through p114RhoGEF-dependent RhoA activationTargeting genomic alterations in squamous cell lung cancer.Liver kinase B1 expression promotes phosphatase activity and abrogation of receptor tyrosine kinase phosphorylation in human cancer cells.LKB1 and AMPK family signaling: the intimate link between cell polarity and energy metabolism.Racial and Ethnic Differences in the Epidemiology and Genomics of Lung Cancer.Molecular changes in smoking-related lung cancer.Genome-wide transcriptional analysis of apoptosis-related genes and pathways regulated by H2AX in lung cancer A549 cells.Role of CPS1 in Cell Growth, Metabolism and Prognosis in LKB1-Inactivated Lung Adenocarcinoma.Mir-155 promotes cervical cancer cell proliferation through suppression of its target gene LKB1.Enhanced antitumor effect of cisplatin in human NSCLC cells by tumor suppressor LKB1.Enhanced activity of the CREB co-activator Crtc1 in LKB1 null lung cancer.Lkb1 deletion in murine B lymphocytes promotes cell death and cancer.Typing tumors using pathways selected by somatic evolution
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on May 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
LKB1 and lung cancer: more than the usual suspects.
@en
LKB1 and lung cancer: more than the usual suspects.
@nl
type
label
LKB1 and lung cancer: more than the usual suspects.
@en
LKB1 and lung cancer: more than the usual suspects.
@nl
prefLabel
LKB1 and lung cancer: more than the usual suspects.
@en
LKB1 and lung cancer: more than the usual suspects.
@nl
P1433
P1476
LKB1 and lung cancer: more than the usual suspects.
@en
P2093
D Neil Hayes
Usman Shah
P304
P356
10.1158/0008-5472.CAN-07-6620
P407
P577
2008-05-01T00:00:00Z