Enhanced activity of the CREB co-activator Crtc1 in LKB1 null lung cancer. - Wikidata - awgldk - TriplyDB

Enhanced activity of the CREB co-activator Crtc1 in LKB1 null lung cancer.

Enhanced activity of the CREB co-activator Crtc1 in LKB1 null lung cancer.

http://www.wikidata.org/entity/Q39763233

about

Integrative analysis of microRNA, mRNA and aCGH data reveals asbestos- and histology-related changes in lung cancer Unsupervised automated high throughput phenotyping of RNAi time-lapse movies Identification and validation of PROM1 and CRTC2 mutations in lung cancer patients CRTC1/MAML2 gain-of-function interactions with MYC create a gene signature predictive of cancers with CREB-MYC involvement.CRTC1 expression during normal and abnormal salivary gland development supports a precursor cell origin for mucoepidermoid cancer.Role of LKB1-CRTC1 on glycosylated COX-2 and response to COX-2 inhibition in lung cancer.The interplay of NR4A receptors and the oncogene-tumor suppressor networks in cancer Lifespan extension induced by AMPK and calcineurin is mediated by CRTC-1 and CREB A unifying gene signature for adenoid cystic cancer identifies parallel MYB-dependent and MYB-independent therapeutic targets.Gene expression profiling analysis of CRTC1-MAML2 fusion oncogene-induced transcriptional program in human mucoepidermoid carcinoma cells.Regulation of triple-negative breast cancer cell metastasis by the tumor-suppressor liver kinase B1.LKB1 loss promotes endometrial cancer progression via CCL2-dependent macrophage recruitment A Sensitive NanoString-Based Assay to Score STK11 (LKB1) Pathway Disruption in Lung Adenocarcinoma.cAMP/CREB-regulated LINC00473 marks LKB1-inactivated lung cancer and mediates tumor growth.The CRTC1-NEDD9 signaling axis mediates lung cancer progression caused by LKB1 loss.The role of LKB1 in lung cancer.Requirement of CRTC1 coactivator for hepatitis B virus transcription LKB1 Loss induces characteristic patterns of gene expression in human tumors associated with NRF2 activation and attenuation of PI3K-AKT.LKB1 as a Tumor Suppressor in Uterine Cancer: Mouse Models and Translational Studies.Drug screening to target nuclear orphan receptor NR4A2 for cancer therapeutics.ATP and noradrenaline activate CREB in astrocytes via noncanonical Ca(2+) and cyclic AMP independent pathways.MMP7-mediated cleavage of nucleolin at Asp255 induces MMP9 expression to promote tumor malignancy.Dysregulated CRTC1 activity is a novel component of PGE2 signaling that contributes to colon cancer growth.

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P2860

Enhanced activity of the CREB co-activator Crtc1 in LKB1 null lung cancer.

http://www.wikidata.org/entity/Q39763233

description

2009 nî lūn-bûn

@nan

2009年の論文

@ja

2009年学术文章

@wuu

2009年学术文章

@zh-cn

2009年学术文章

@zh-hans

2009年学术文章

@zh-my

2009年学术文章

@zh-sg

2009年學術文章

@yue

2009年學術文章

@zh

2009年學術文章

@zh-hant

name

Enhanced activity of the CREB co-activator Crtc1 in LKB1 null lung cancer.

@en

Enhanced activity of the CREB co-activator Crtc1 in LKB1 null lung cancer.

@nl

type

label

Enhanced activity of the CREB co-activator Crtc1 in LKB1 null lung cancer.

@en

Enhanced activity of the CREB co-activator Crtc1 in LKB1 null lung cancer.

@nl

prefLabel

Enhanced activity of the CREB co-activator Crtc1 in LKB1 null lung cancer.

@en

Enhanced activity of the CREB co-activator Crtc1 in LKB1 null lung cancer.

@nl

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P1476

Enhanced activity of the CREB co-activator Crtc1 in LKB1 null lung cancer

@en

P2093

A Coxon

http://www.w3.org/2001/XMLSchema#string

F J Kaye

http://www.w3.org/2001/XMLSchema#string

M Zajac-Kaye

http://www.w3.org/2001/XMLSchema#string

P Meltzer

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T Komiya

http://www.w3.org/2001/XMLSchema#string

W-D Chen

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Y Park

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P2860

Complexes between the LKB1 tumor suppressor, STRAD alpha/beta and MO25 alpha/beta are upstream kinases in the AMP-activated protein kinase cascade

Identification of a family of cAMP response element-binding protein coactivators by genome-scale functional analysis in mammalian cells

TORCs: transducers of regulated CREB activity

Cooperative interactions between CBP and TORC2 confer selectivity to CREB target gene expression

LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1

SIK1 couples LKB1 to p53-dependent anoikis and suppresses metastasis

Transforming activity of MECT1-MAML2 fusion oncoprotein is mediated by constitutive CREB activation

TORC1 is a calcium- and cAMP-sensitive coincidence detector involved in hippocampal long-term synaptic plasticity

Activation of yeast Snf1 and mammalian AMP-activated protein kinase by upstream kinases.

t(11;19)(q21;p13) translocation in mucoepidermoid carcinoma creates a novel fusion product that disrupts a Notch signaling pathway

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1672-1680

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10.1038/ONC.2009.453

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11

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29

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Tatiana Karpova

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2009-12-14T00:00:00Z

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20010869

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