Phenotypes and tolerances in the design space of biochemical systems.
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Relating mutant genotype to phenotype via quantitative behavior of the NADPH redox cycle in human erythrocytesTrade-offs and constraints in allosteric sensingBiological robustness: paradigms, mechanisms, and systems principlesGrowth landscape formed by perception and import of glucose in yeastDuplication frequency in a population of Salmonella enterica rapidly approaches steady state with or without recombination.Regulatory design governing progression of population growth phases in bacteriaUnderstanding regulation of metabolism through feasibility analysis.Automated construction and analysis of the design space for biochemical systemsBiomedical engineering strategies in system design space.Phenotypic repertoire of the FNR regulatory network in Escherichia coli.Analysis of operating principles with S-system models.Design of the lac gene circuit revisited.A Bone Anabolic Effect of RANKL in a Murine Model of Osteoporosis Mediated Through FoxP3+ CD8 T Cells.Design Space Toolbox V2: Automated Software Enabling a Novel Phenotype-Centric Modeling Strategy for Natural and Synthetic Biological Systems.Phenotypic deconstruction of gene circuitryMolecular mechanisms of multiple toxin-antitoxin systems are coordinated to govern the persister phenotypeComplex systems: from chemistry to systems biology.Qualitatively distinct phenotypes in the design space of biochemical systems.Systems analysis of cellular networks under uncertainty.The systems biology of mitochondrial fission and fusion and implications for disease and aging.Model-based genotype-phenotype mapping used to investigate gene signatures of immune sensitivity and resistance in melanoma micrometastasis.Elucidating the genotype-phenotype map by automatic enumeration and analysis of the phenotypic repertoire.The best models of metabolism.A Geometric Method for Model Reduction of Biochemical Networks with Polynomial Rate Functions.Rapid Discrimination Among Putative Mechanistic Models of Biochemical SystemsSynthetic in vitro transcriptional oscillators.Unrelated toxin-antitoxin systems cooperate to induce persistence.Time Hierarchies and Model Reduction in Canonical Non-linear Models.Computational analysis of target hub gene repression regulated by multiple and cooperative miRNAs.Architecture-dependent robustness and bistability in a class of genetic circuits.Strategy revealing phenotypic differences among synthetic oscillator designs.Mapping the phenotypic repertoire of the cytoplasmic 2-Cys peroxiredoxin - Thioredoxin system. 1. Understanding commonalities and differences among cell types.Biochemical Systems Theory: A Review
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P2860
Phenotypes and tolerances in the design space of biochemical systems.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 11 March 2009
@en
vedecký článok
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vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
@cs
name
Phenotypes and tolerances in the design space of biochemical systems.
@en
Phenotypes and tolerances in the design space of biochemical systems.
@nl
type
label
Phenotypes and tolerances in the design space of biochemical systems.
@en
Phenotypes and tolerances in the design space of biochemical systems.
@nl
prefLabel
Phenotypes and tolerances in the design space of biochemical systems.
@en
Phenotypes and tolerances in the design space of biochemical systems.
@nl
P2093
P2860
P356
P1476
Phenotypes and tolerances in the design space of biochemical systems.
@en
P2093
Armindo Salvador
Dean A Tolla
Michael A Savageau
Pedro M B M Coelho
Rick A Fasani
P2860
P304
P356
10.1073/PNAS.0809869106
P407
P577
2009-03-11T00:00:00Z