Mitochondrial-targeted peptide rapidly improves mitochondrial energetics and skeletal muscle performance in aged mice. - Wikidata - awgldk - TriplyDB

Mitochondrial-targeted peptide rapidly improves mitochondrial energetics and skeletal muscle performance in aged mice.

Mitochondrial-targeted peptide rapidly improves mitochondrial energetics and skeletal muscle performance in aged mice.

http://www.wikidata.org/entity/Q37170429

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The Measurement of Reversible Redox Dependent Post-translational Modifications and Their Regulation of Mitochondrial and Skeletal Muscle Function Mitochondrial involvement and impact in aging skeletal muscle Mitochondrial oxidative stress in aging and healthspan Targeting mitochondrial cardiolipin and the cytochrome c/cardiolipin complex to promote electron transport and optimize mitochondrial ATP synthesis First-in-class cardiolipin-protective compound as a therapeutic agent to restore mitochondrial bioenergetics Serendipity and the discovery of novel compounds that restore mitochondrial plasticity Mitochondria-targeted antioxidant preserves contractile properties and mitochondrial function of skeletal muscle in aged rats Mitochondria and ageing: role in heart, skeletal muscle and adipose tissue.Cyclophosphamide leads to persistent deficits in physical performance and in vivo mitochondria function in a mouse model of chemotherapy late effects.Mitochondrial reactive oxygen species at the heart of the matter: new therapeutic approaches for cardiovascular diseases.A Mitochondrion-Targeted Antioxidant Ameliorates Isoflurane-Induced Cognitive Deficits in Aging Mice Eicosapentaenoic acid but not docosahexaenoic acid restores skeletal muscle mitochondrial oxidative capacity in old mice Chronic Therapy With Elamipretide (MTP-131), a Novel Mitochondria-Targeting Peptide, Improves Left Ventricular and Mitochondrial Function in Dogs With Advanced Heart Failure.Bendavia restores mitochondrial energy metabolism gene expression and suppresses cardiac fibrosis in the border zone of the infarcted heart.Mitochondrial ROS regulate oxidative damage and mitophagy but not age-related muscle fiber atrophy Age-dependent changes in mitochondrial morphology and volume are not predictors of lifespan.Expert consensus document: Mitochondrial function as a therapeutic target in heart failure Nitric Oxide Regulates Skeletal Muscle Fatigue, Fiber Type, Microtubule Organization, and Mitochondrial ATP Synthesis Efficiency Through cGMP-Dependent Mechanisms.Advances in Therapeutic Approaches to Extend Healthspan: a perspective from the 2nd Scripps Symposium on the Biology of Aging.In the idiopathic inflammatory myopathies (IIM), do reactive oxygen species (ROS) contribute to muscle weakness?Redox homeostasis and age-related deficits in neuromuscular integrity and function.Mitochondria-Targeted Antioxidants for the Treatment of Cardiovascular Disorders.Evaluation of in vivo mitochondrial bioenergetics in skeletal muscle using NMR and optical methods Beneficial effects of exercise on age-related mitochondrial dysfunction and oxidative stress in skeletal muscle.Protective Effects of Antioxidant Peptide SS-31 Against Multiple Organ Dysfunctions During Endotoxemia.A mitochondrial therapeutic reverses visual decline in mouse models of diabetes Pharynx mitochondrial [Ca2+] dynamics in live C. elegans worms during aging.Mitofusin 1 and optic atrophy 1 shift metabolism to mitochondrial respiration during aging.Mitochondrial-Targeted Antioxidant Maintains Blood Flow, Mitochondrial Function, and Redox Balance in Old Mice Following Prolonged Limb Ischemia.In vivo high-resolution magic angle spinning magnetic and electron paramagnetic resonance spectroscopic analysis of mitochondria-targeted peptide in Drosophila melanogaster with trauma-induced thoracic injury.Mitochondrial Dysfunction in Cardiovascular Aging.Extension of Health Span and Life Span in Drosophila by S107 Requires the calstabin Homologue FK506-BP2.Denervation drives mitochondrial dysfunction in skeletal muscle of octogenarians.Antioxidant treatments do not improve force recovery after fatiguing stimulation of mouse skeletal muscle fibres.A mitochondrial-targeted antioxidant improves myofilament Ca2+ sensitivity during prolonged low frequency force depression at low PO2.Targeting mitochondrial function and proteostasis to mitigate dynapenia.Mitoprotection attenuates myocardial vascular impairment in porcine metabolic syndrome.Treatment with the mitochondrial-targeted antioxidant peptide SS-31 rescues neurovascular coupling responses and cerebrovascular endothelial function and improves cognition in aged mice.The mitochondrial-targeted peptide, SS-31, improves glomerular architecture in mice of advanced age.Polymer Functionalization of Isolated Mitochondria for Cellular Transplantation and Metabolic Phenotype Alteration.

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Mitochondrial-targeted peptide rapidly improves mitochondrial energetics and skeletal muscle performance in aged mice.

http://www.wikidata.org/entity/Q37170429

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 11 June 2013

@en

vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Mitochondrial-targeted peptide ...... scle performance in aged mice.

@en

Mitochondrial-targeted peptide ...... scle performance in aged mice.

@nl

type

label

Mitochondrial-targeted peptide ...... scle performance in aged mice.

@en

Mitochondrial-targeted peptide ...... scle performance in aged mice.

@nl

prefLabel

Mitochondrial-targeted peptide ...... scle performance in aged mice.

@en

Mitochondrial-targeted peptide ...... scle performance in aged mice.

@nl

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Mitochondrial-targeted peptide ...... uscle performance in aged mice

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P2093

Collin C White

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Hazel H Szeto

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Heather C Hopkins

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Justin M Percival

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Terrance J Kavanagh

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P2860

Extension of murine life span by overexpression of catalase targeted to mitochondria

Topology of superoxide production from different sites in the mitochondrial electron transport chain

NMR spectral analysis of kinetic data using natural lineshapes.

Invited Review: contractile activity-induced mitochondrial biogenesis in skeletal muscle.

Functional deficits in nNOSmu-deficient skeletal muscle: myopathy in nNOS knockout mice

Ectopic catalase expression in mitochondria by adeno-associated virus enhances exercise performance in mice.

Mitochondria targeted peptides protect against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity.

Reversible inhibition of alpha-ketoglutarate dehydrogenase by hydrogen peroxide: glutathionylation and protection of lipoic acid.

α-Ketoglutarate dehydrogenase: a mitochondrial redox sensor

Reduced coupling of oxidative phosphorylation in vivo precedes electron transport chain defects due to mild oxidative stress in mice.

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scholarly article

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10.1111/ACEL.12102

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5

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12

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Michael P Siegel

P S Rabinovitch

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2013-06-11T00:00:00Z

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236926716

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3772966

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