Stabilization of the μ-opioid receptor by truncated single transmembrane splice variants through a chaperone-like action. - Wikidata - awgldk - TriplyDB

Stabilization of the μ-opioid receptor by truncated single transmembrane splice variants through a chaperone-like action.

Stabilization of the μ-opioid receptor by truncated single transmembrane splice variants through a chaperone-like action.

http://www.wikidata.org/entity/Q37175164

about

Opiate pharmacology and relief of pain.Chaperoning G protein-coupled receptors: from cell biology to therapeutics A heroin addiction severity-associated intronic single nucleotide polymorphism modulates alternative pre-mRNA splicing of the μ opioid receptor gene OPRM1 via hnRNPH interactions.Pharmacologic characterization in the rat of a potent analgesic lacking respiratory depression, IBNtxA.Differential expressions of the alternatively spliced variant mRNAs of the µ opioid receptor gene, OPRM1, in brain regions of four inbred mouse strains Mu Opioid Splice Variant MOR-1K Contributes to the Development of Opioid-Induced Hyperalgesia.Mediation of opioid analgesia by a truncated 6-transmembrane GPCR.Splice variation of the mu-opioid receptor and its effect on the action of opioids.Regulation and Functional Implications of Opioid Receptor Splicing in Opioid Pharmacology and HIV Pathogenesis Truncated mu opioid GPCR variant involvement in opioid-dependent and opioid-independent pain modulatory systems within the CNS.Taking two to tango: a role for ghrelin receptor heterodimerization in stress and reward.Mu opioids and their receptors: evolution of a concept.Alternative Splicing of G Protein-Coupled Receptors: Relevance to Pain Management.Isolating and characterizing three alternatively spliced mu opioid receptor variants: mMOR-1A, mMOR-1O, and mMOR-1P.Alternatively spliced mu opioid receptor C termini impact the diverse actions of morphine.A "tail" of opioid receptor variants.Tetrapeptide Endomorphin Analogs Require Both Full Length and Truncated Splice Variants of the Mu Opioid Receptor Gene Oprm1 for Analgesia.Mediation of buprenorphine analgesia by a combination of traditional and truncated mu opioid receptor splice variants.Isolation and characterization of alternatively spliced variants of the mouse sigma1 receptor gene, Sigmar1.Truncated μ-Opioid Receptors With 6 Transmembrane Domains Are Essential for Opioid Analgesia.Genetic dissociation of morphine analgesia from hyperalgesia in mice.

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Stabilization of the μ-opioid receptor by truncated single transmembrane splice variants through a chaperone-like action.

http://www.wikidata.org/entity/Q37175164

description

article científic

@ca

article scientifique

@fr

articolo scientifico

@it

artigo científico

@pt

bilimsel makale

@tr

scientific article published on 11 June 2013

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

Stabilization of the μ-opioid ...... rough a chaperone-like action.

@en

Stabilization of the μ-opioid ...... rough a chaperone-like action.

@nl

type

label

Stabilization of the μ-opioid ...... rough a chaperone-like action.

@en

Stabilization of the μ-opioid ...... rough a chaperone-like action.

@nl

prefLabel

Stabilization of the μ-opioid ...... rough a chaperone-like action.

@en

Stabilization of the μ-opioid ...... rough a chaperone-like action.

@nl

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P356

JBC.M113.458687

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Journal of Biological Chemistry

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Stabilization of the μ-opioid ...... hrough a chaperone-like action

@en

P2093

Charles E Inturrisi

http://www.w3.org/2001/XMLSchema#string

Gavril W Pasternak

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Grace C Rossi

http://www.w3.org/2001/XMLSchema#string

Jin Xu

http://www.w3.org/2001/XMLSchema#string

Ming Xu

http://www.w3.org/2001/XMLSchema#string

Ying-Xian Pan

http://www.w3.org/2001/XMLSchema#string

P2860

G-protein-coupled receptor heterodimerization modulates receptor function

Crystal structure of the µ-opioid receptor bound to a morphinan antagonist

Heterodimerization of mu and delta opioid receptors: A role in opiate synergy

Oligomerization of opioid receptors with beta 2-adrenergic receptors: a role in trafficking and mitogen-activated protein kinase activation

Ligands regulate cell surface level of the human kappa opioid receptor by activation-induced down-regulation and pharmacological chaperone-mediated enhancement: differential effects of nonpeptide and peptide agonists.

Characterizing exons 11 and 1 promoters of the mu opioid receptor (Oprm) gene in transgenic mice.

Generation of the mu opioid receptor (MOR-1) protein by three new splice variants of the Oprm gene.

Truncated G protein-coupled mu opioid receptor MOR-1 splice variants are targets for highly potent opioid analgesics lacking side effects.

Synthesis and evaluation of aryl-naloxamide opiate analgesics targeting truncated exon 11-associated μ opioid receptor (MOR-1) splice variants.

Mechanistic links between nonsense-mediated mRNA decay and pre-mRNA splicing in mammalian cells.

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21211-21227

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scholarly article

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10.1074/JBC.M113.458687

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29

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2013-06-11T00:00:00Z

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23760268

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molecular chaperones

transmembrane protein

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3774389

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