Isolating and characterizing three alternatively spliced mu opioid receptor variants: mMOR-1A, mMOR-1O, and mMOR-1P. - Wikidata - awgldk - TriplyDB

Isolating and characterizing three alternatively spliced mu opioid receptor variants: mMOR-1A, mMOR-1O, and mMOR-1P.

Isolating and characterizing three alternatively spliced mu opioid receptor variants: mMOR-1A, mMOR-1O, and mMOR-1P.

http://www.wikidata.org/entity/Q37588798

about

Broad-spectrum analgesic efficacy of IBNtxA is mediated by exon 11-associated splice variants of the mu-opioid receptor gene.Opioids and their receptors: Are we there yet?Interactions of HIV and drugs of abuse: the importance of glia, neural progenitors, and host genetic factors.Splice variation of the mu-opioid receptor and its effect on the action of opioids.Regulation and Functional Implications of Opioid Receptor Splicing in Opioid Pharmacology and HIV Pathogenesis Ligand-biased activation of extracellular signal-regulated kinase 1/2 leads to differences in opioid induced antinociception and tolerance.Morphine-induced MOR-1X and ASF/SF2 Expressions Are Independent of Transcriptional Regulation: Implications for MOR-1X Signaling Morphine regulates expression of μ-opioid receptor MOR-1A, an intron-retention carboxyl terminal splice variant of the μ-opioid receptor (OPRM1) gene via miR-103/miR-107.Alternatively spliced mu opioid receptor C termini impact the diverse actions of morphine.

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Isolating and characterizing three alternatively spliced mu opioid receptor variants: mMOR-1A, mMOR-1O, and mMOR-1P.

http://www.wikidata.org/entity/Q37588798

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 16 January 2014

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Isolating and characterizing t ...... mMOR-1A, mMOR-1O, and mMOR-1P.

@en

Isolating and characterizing t ...... mMOR-1A, mMOR-1O, and mMOR-1P.

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type

label

Isolating and characterizing t ...... mMOR-1A, mMOR-1O, and mMOR-1P.

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Isolating and characterizing t ...... mMOR-1A, mMOR-1O, and mMOR-1P.

@nl

prefLabel

Isolating and characterizing t ...... mMOR-1A, mMOR-1O, and mMOR-1P.

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Isolating and characterizing t ...... mMOR-1A, mMOR-1O, and mMOR-1P.

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Isolating and characterizing t ...... mMOR-1A, mMOR-1O, and mMOR-1P.

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Annie-Kim Gilbert

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Elizabeth Bolan

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Gavril W Pasternak

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Jin Xu

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Mingming Xu

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Ying-Xian Pan

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P2860

Protein measurement with the Folin phenol reagent

Unidirectional cross-activation of GRPR by MOR1D uncouples itch and analgesia induced by opioids

Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

Identification and characterization of six new alternatively spliced variants of the human mu opioid receptor gene, Oprm

Identification of three new alternatively spliced variants of the rat mu opioid receptor gene: dissociation of affinity and efficacy

Prediction of post-translational glycosylation and phosphorylation of proteins from the amino acid sequence

Characterizing exons 11 and 1 promoters of the mu opioid receptor (Oprm) gene in transgenic mice.

Generation of the mu opioid receptor (MOR-1) protein by three new splice variants of the Oprm gene.

Truncated G protein-coupled mu opioid receptor MOR-1 splice variants are targets for highly potent opioid analgesics lacking side effects.

Synthesis and evaluation of aryl-naloxamide opiate analgesics targeting truncated exon 11-associated μ opioid receptor (MOR-1) splice variants.

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144-152

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scholarly article

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10.1002/SYN.21727

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4

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68

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2014-01-16T00:00:00Z

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