Kynurenine pathway inhibition reduces central nervous system inflammation in a model of human African trypanosomiasis.
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Kynurenines in the mammalian brain: when physiology meets pathologyBiochemical identification and crystal structure of kynurenine formamidase from Drosophila melanogasterElevated cerebrospinal fluid kynurenic acid levels in patients with tick-borne encephalitisTrypanosoma brucei glycogen synthase kinase-3, a target for anti-trypanosomal drug development: a public-private partnership to identify novel leadsSiderophores; iron scavengers: the novel & promising targets for pathogen specific antifungal therapy.Cerebral and peripheral changes occurring in nitric oxide (NO) synthesis in a rat model of sleeping sickness: identification of brain iNOS expressing cells.Kynurenine Pathway Activation in Human African TrypanosomiasisKynurenine pathway inhibition as a therapeutic strategy for neuroprotection.My life as a clinician-scientist: trying to bridge the perceived gap between medicine and science.Magnetic resonance imaging to assess blood-brain barrier damage in murine trypanosomiasis.Kynurenine 3-monooxygenase inhibition in blood ameliorates neurodegeneration.Prenatal inhibition of the kynurenine pathway leads to structural changes in the hippocampus of adult rat offspring.Kynurenine pathway metabolism following prenatal KMO inhibition and in Mecp2(+/-) mice, using liquid chromatography-tandem mass spectrometry.Metabolomics Identifies Multiple Candidate Biomarkers to Diagnose and Stage Human African Trypanosomiasis.Delineating neuroinflammation, parasite CNS invasion, and blood-brain barrier dysfunction in an experimental murine model of human African trypanosomiasisIn vivo metabolism of tryptophan in meningiomas is mediated by indoleamine 2,3-dioxygenase 1.The kynurenine pathway as a therapeutic target in cognitive and neurodegenerative disorders.A fluorescence polarization binding assay to identify inhibitors of flavin-dependent monooxygenases.Trypanosomiasis and the brain.Involvement of kynurenines in Huntington's disease and stroke-induced brain damage.Inhibitors of the kynurenine pathway as neurotherapeutics: a patent review (2012-2015).Erythrina abyssinica prevents meningoencephalitis in chronic Trypanosoma brucei brucei mouse model.Inhibition of the kynurenine-NAD+ pathway leads to energy failure and exacerbates apoptosis in pneumococcal meningitis.Kynurenine metabolism predicts cognitive function in patients following cardiac bypass and thoracic surgery.New insights in staging and chemotherapy of African trypanosomiasis and possible contribution of medicinal plants.
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P2860
Kynurenine pathway inhibition reduces central nervous system inflammation in a model of human African trypanosomiasis.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 31 March 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Kynurenine pathway inhibition ...... human African trypanosomiasis.
@en
Kynurenine pathway inhibition ...... human African trypanosomiasis.
@nl
type
label
Kynurenine pathway inhibition ...... human African trypanosomiasis.
@en
Kynurenine pathway inhibition ...... human African trypanosomiasis.
@nl
prefLabel
Kynurenine pathway inhibition ...... human African trypanosomiasis.
@en
Kynurenine pathway inhibition ...... human African trypanosomiasis.
@nl
P2093
P2860
P50
P921
P356
P1433
P1476
Kynurenine pathway inhibition ...... human African trypanosomiasis.
@en
P2093
Barbara Bradley
Michael P Barrett
Peter G E Kennedy
P2860
P304
P356
10.1093/BRAIN/AWP074
P407
P577
2009-03-31T00:00:00Z