IL-23, not IL-12, directs autoimmunity to the Goodpasture antigen.
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NF-κB in inflammation and renal diseasesThe role of Th1 and Th17 cells in glomerulonephritis.Stat3 programs Th17-specific regulatory T cells to control GN.Th17 cells promote autoimmune anti-myeloperoxidase glomerulonephritis.CCR6 recruits regulatory T cells and Th17 cells to the kidney in glomerulonephritis.An essential role of interleukin-17 receptor signaling in the development of autoimmune glomerulonephritisKidney Dendritic Cells Become Pathogenic during Crescentic Glomerulonephritis with Proteinuria.The Th17-defining transcription factor RORγt promotes glomerulonephritisLipocalin-2 expressed in innate immune cells is an endogenous inhibitor of inflammation in murine nephrotoxic serum nephritis.Interleukin-17A promotes early but attenuates established disease in crescentic glomerulonephritis in mice.Asymptomatic autoantibodies associate with future anti-glomerular basement membrane diseaseLocal IL-17 Production Exerts a Protective Role in Murine Experimental Glomerulonephritis.The HLA-DRB1*15:01-restricted Goodpasture's T cell epitope induces GN.Epitope specificity determines pathogenicity and detectability in ANCA-associated vasculitis.Leptin deficiency down-regulates IL-23 production in glomerular podocytes resulting in an attenuated immune response in nephrotoxic serum nephritis.Regulation of pathogenic Th17 cell differentiation by IL-10 in the development of glomerulonephritis.Th1 and Th17 cells induce proliferative glomerulonephritis.Interleukin-1 accounts for intrarenal Th17 cell activation during ureteral obstruction.Targeting IL-23 in human diseases.Strain differences and the genetic basis of experimental autoimmune anti-glomerular basement membrane glomerulonephritis.Advances in human antiglomerular basement membrane disease.Interleukin-23 as a potential therapeutic target for rheumatoid arthritis.Pivotal roles of T-helper 17-related cytokines, IL-17, IL-22, and IL-23, in inflammatory diseases.T cell mediated autoimmune glomerular disease in mice.Biologics for the treatment of autoimmune renal diseases.IL-9 production by regulatory T cells recruits mast cells that are essential for regulatory T cell-induced immune suppression.Plasticity of Th17 Cells in Autoimmune Kidney Diseases.T cell infiltration is associated with kidney injury in patients with anti-glomerular basement membrane disease.Dominant protection from HLA-linked autoimmunity by antigen-specific regulatory T cells.IL-17A production by renal γδ T cells promotes kidney injury in crescentic GN.Serum IL-17 and IL-23 levels and autoantigen-specific Th17 cells are elevated in patients with ANCA-associated vasculitis.Renal IL-17 expression in human ANCA-associated glomerulonephritis.T helper type 17 cells in immune-mediated glomerular disease.Programmed death 1 and its ligands do not limit experimental foreign antigen-induced immune complex glomerulonephritis.Cln 3-requiring 9 is a negative regulator of Th17 pathway-driven inflammation in anti-glomerular basement membrane glomerulonephritis.TH1 and TH17 cells promote crescent formation in experimental autoimmune glomerulonephritis.
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P2860
IL-23, not IL-12, directs autoimmunity to the Goodpasture antigen.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 08 April 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
IL-23, not IL-12, directs autoimmunity to the Goodpasture antigen.
@en
IL-23, not IL-12, directs autoimmunity to the Goodpasture antigen.
@nl
type
label
IL-23, not IL-12, directs autoimmunity to the Goodpasture antigen.
@en
IL-23, not IL-12, directs autoimmunity to the Goodpasture antigen.
@nl
prefLabel
IL-23, not IL-12, directs autoimmunity to the Goodpasture antigen.
@en
IL-23, not IL-12, directs autoimmunity to the Goodpasture antigen.
@nl
P2093
P2860
P356
P1476
IL-23, not IL-12, directs autoimmunity to the Goodpasture antigen.
@en
P2093
A Richard Kitching
Joshua D Ooi
Richard K S Phoon
Stephen R Holdsworth
P2860
P304
P356
10.1681/ASN.2008080891
P577
2009-04-08T00:00:00Z