Vascular injury during elevated glucose can be mitigated by erythropoietin and Wnt signaling.
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Novel nervous and multi-system regenerative therapeutic strategies for diabetes mellitus with mTORErythropoietin and diabetes mellitusThe Effects of Chinese Medicine on Activation of Wnt/β-Catenin Signal Pathway under High Glucose ConditionStem cell guidance through the mechanistic target of rapamycinFoxO Transcription Factors and Regenerative Pathways in Diabetes MellitusErythropoietin: new directions for the nervous systemTargeting disease through novel pathways of apoptosis and autophagyErythropoietin and mTOR: A "One-Two Punch" for Aging-Related Disorders Accompanied by Enhanced Life ExpectancyNew Insights for Oxidative Stress and Diabetes MellitusNovel applications of trophic factors, Wnt and WISP for neuronal repair and regeneration in metabolic diseaseKnockdown of GSK3β increases basal autophagy and AMPK signalling in nutrient-laden human aortic endothelial cellsOxidative stress: Biomarkers and novel therapeutic pathways.New strategies for Alzheimer's disease and cognitive impairment.Diabetes mellitus: channeling care through cellular discoveryFOXO3a governs early and late apoptotic endothelial programs during elevated glucose through mitochondrial and caspase signaling.The "O" class: crafting clinical care with FoxO transcription factors.Early apoptotic vascular signaling is determined by Sirt1 through nuclear shuttling, forkhead trafficking, bad, and mitochondrial caspase activation.Wnt1, FoxO3a, and NF-kappaB oversee microglial integrity and activation during oxidant stress.Wnt1 neuroprotection translates into improved neurological function during oxidant stress and cerebral ischemia through AKT1 and mitochondrial apoptotic pathways.WISP1: Clinical insights for a proliferative and restorative member of the CCN familyThe vasculome of the mouse brain.Novel avenues of drug discovery and biomarkers for diabetes mellitus.EPO relies upon novel signaling of Wnt1 that requires Akt1, FoxO3a, GSK-3β, and β-catenin to foster vascular integrity during experimental diabetes.Erythropoietin employs cell longevity pathways of SIRT1 to foster endothelial vascular integrity during oxidant stress.Translating cell survival and cell longevity into treatment strategies with SIRT1Erythropoietin and Wnt1 govern pathways of mTOR, Apaf-1, and XIAP in inflammatory microglia.Wnt1 inducible signaling pathway protein 1 (WISP1) blocks neurodegeneration through phosphoinositide 3 kinase/Akt1 and apoptotic mitochondrial signaling involving Bad, Bax, Bim, and Bcl-xLHigh-Fat Diet/Low-Dose Streptozotocin-Induced Type 2 Diabetes in Rats Impacts Osteogenesis and Wnt Signaling in Bone Marrow Stromal CellsThe effects of sodium tanshinone IIa sulfonate pretreatment on high glucose-induced expression of fractalkine and apoptosis in human umbilical vein endothelial cells.Prevention of β-amyloid degeneration of microglia by erythropoietin depends on Wnt1, the PI 3-K/mTOR pathway, Bad, and Bcl-xL.Glycogen synthase kinase 3 inhibitor protects against microvascular hyperpermeability following hemorrhagic shock.Mammalian target of rapamycin signaling in diabetic cardiovascular diseaseRegeneration in the nervous system with erythropoietinTherapeutic potential of a monoclonal antibody blocking the Wnt pathway in diabetic retinopathyNovel directions for diabetes mellitus drug discoveryRaves and risks for erythropoietinTriple play: promoting neurovascular longevity with nicotinamide, WNT, and erythropoietin in diabetes mellitus.The Wnt signaling pathway: aging gracefully as a protectionist?Erythropoietin: elucidating new cellular targets that broaden therapeutic strategies"Sly as a FOXO": new paths with Forkhead signaling in the brain
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Vascular injury during elevated glucose can be mitigated by erythropoietin and Wnt signaling.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on August 2007
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Vascular injury during elevate ...... thropoietin and Wnt signaling.
@en
Vascular injury during elevate ...... thropoietin and Wnt signaling.
@nl
type
label
Vascular injury during elevate ...... thropoietin and Wnt signaling.
@en
Vascular injury during elevate ...... thropoietin and Wnt signaling.
@nl
prefLabel
Vascular injury during elevate ...... thropoietin and Wnt signaling.
@en
Vascular injury during elevate ...... thropoietin and Wnt signaling.
@nl
P2093
P2860
P921
P1476
Vascular injury during elevate ...... thropoietin and Wnt signaling.
@en
P2093
Kenneth Maiese
Yan Chen Shang
Zhao Zhong Chong
P2860
P304
P356
10.2174/156720207781387150
P577
2007-08-01T00:00:00Z