Specific function of phosphoinositide 3-kinase beta in the control of DNA replication.
about
Purinergic receptor-mediated rapid depletion of nuclear phosphorylated Akt depends on pleckstrin homology domain leucine-rich repeat phosphatase, calcineurin, protein phosphatase 2A, and PTEN phosphatasesNuclear PI3K signaling in cell growth and tumorigenesisPhosphoinositides: tiny lipids with giant impact on cell regulationStructure of Lipid Kinase p110β/p85β Elucidates an Unusual SH2-Domain-Mediated Inhibitory MechanismFlexibility of PCNA-protein interface accommodates differential binding partnersNuclear phosphoinositide 3-kinase beta controls double-strand break DNA repair.Phosphoinositide 3-kinase β regulates chromosome segregation in mitosis.Essential role of the p110beta subunit of phosphoinositide 3-OH kinase in male fertility.The Spi1/PU.1 transcription factor accelerates replication fork progression by increasing PP1 phosphatase in leukemiaA constitutively activated form of the p110beta isoform of PI3-kinase induces prostatic intraepithelial neoplasia in mice.Mammary gland morphological and gene expression changes underlying pregnancy protection of breast cancer tumorigenesisATR mediates a checkpoint at the nuclear envelope in response to mechanical stress.The p110α and p110β isoforms of class I phosphatidylinositol 3-kinase are involved in toll-like receptor 5 signaling in epithelial cellsNuclear but not cytosolic phosphoinositide 3-kinase beta has an essential function in cell survivalElevated PI3K signaling drives multiple breast cancer subtypes.Estrogen-mediated inactivation of FOXO3a by the G protein-coupled estrogen receptor GPER.The phosphoinositide-3-kinase (PI3K)-delta and gamma inhibitor, IPI-145 (Duvelisib), overcomes signals from the PI3K/AKT/S6 pathway and promotes apoptosis in CLL.SiRNA Targeting mTOR Effectively Prevents the Proliferation and Migration of Human Lens Epithelial CellsTargeted depletion of PIK3R2 induces regression of lung squamous cell carcinomaNuclear phosphoinositides and their roles in cell biology and disease.Nuclear phosphoinositides and their impact on nuclear functions.PI-3 kinase p110β: a therapeutic target in advanced prostate cancers.Inhibition of class IA PI3K enzymes in non-small cell lung cancer cells uncovers functional compensation among isoforms.p110α and p110β isoforms of PI3K signaling: are they two sides of the same coin?Cell activation-induced phosphoinositide 3-kinase alpha/beta dimerization regulates PTEN activity.Decatenation checkpoint-defective melanomas are dependent on PI3K for survival.Nuclear DNA replication and repair in parasites of the genus Leishmania: Exploiting differences to develop innovative therapeutic approaches.The secret life of kinases: functions beyond catalysisPhosphoinositide 3-kinase beta controls replication factor C assembly and function.PI3K p110 alpha and p110 beta have differential effects on Akt activation and protection against oxidative stress-induced apoptosis in myoblasts.Phosphoinositide 3-kinase beta protects nuclear envelope integrity by controlling RCC1 localization and Ran activity.Endometrial cancer cells exhibit high expression of p110β and its selective inhibition induces variable responses on PI3K signaling, cell survival and proliferation.E-cadherin downregulation sensitizes PTEN-mutant tumors to PI3Kβ silencing.Effects of PI3K catalytic subunit and Akt isoform deficiency on mTOR and p70S6K activation in myoblastsPIK3CA gene alterations in bladder cancer are frequent and associate with reduced recurrence in non-muscle invasive tumors.Dynamics of GFP-Fusion p110α and p110β Isoforms of PI3K Signaling Pathway in Normal and Cancer Cells.CXCL12-mediated murine neural progenitor cell movement requires PI3Kβ activation.
P2860
Q24337816-7371823B-F613-4443-B27C-F39BEABA2A85Q26859127-8009CEC0-5CC3-4714-B402-FD9CB78CCEFEQ27012953-1FAED65A-7D11-4F9A-8EB8-5840DC62840CQ27667112-AA77CED3-87B4-431E-B352-374B159EA533Q28540911-A746B0C8-2C3F-4738-AE17-8D7195C3F070Q30494441-3F8E412F-DEE4-4C96-B6E9-41C9825779BDQ30528812-ED9AD477-16BF-4213-909C-11EE230F0744Q33689775-2BADCA4C-61BB-4112-BD1D-8FA91CFD43CDQ33913826-062D6CF4-4382-41C0-BD35-001A2C49934CQ33934457-D47ED8E8-C3B2-4E7B-892A-7BDB9DF40060Q33976295-78756BA1-9F12-4920-B211-50458D362EEDQ34001058-F5A16408-09BC-4E1E-A9DD-C901693728DCQ34189683-BC955F66-C7E8-435B-980F-E07797FC1FFFQ35096551-4478E280-100B-4B99-BDAA-CCC352AED7BFQ35640263-B8BC8531-CCAE-4F26-8790-C8CAB98B1A9AQ35809173-DCA719B8-A905-46DF-9B8A-8FD19C35969DQ36021849-5015ED6E-F1AB-4207-809E-AC96ACA50BEEQ36211932-F27C658B-44ED-47D3-9D01-498269D45091Q37709086-E0C1B975-3007-463F-8AA0-011D23B0363AQ37931279-AED9EC57-26D1-4AB8-95D6-DB7878B971D3Q38151274-6DDC6DC2-2594-486D-B9FE-D8C6E3CC286EQ38265574-3DF4D314-0FEE-4BA1-8E01-C0BEEAB28F55Q38852858-222570F3-CC53-43A2-B815-B0EFBC80B60DQ38934741-450DB4C3-1875-4DB8-8F62-B172DED84F05Q38981868-B2345226-0A23-44D4-A891-EA7D0CC55F63Q38988931-1264F8F1-7BF6-49B0-B2EB-F2AEF04908D8Q39037726-F9DD628D-9638-40FD-9E13-29B96D7886C8Q39077751-40F66344-7622-4B48-B68D-A1FBF4E2E54AQ39240233-63857C69-61FF-4DD2-A092-1F9167250E73Q39634639-C34CB322-152E-4361-BD9D-D21670210DD2Q42015294-349835FC-83F4-4C6B-A160-8A685BD123E4Q42030378-2F3C49A2-E305-45E6-9932-6CD0BD07AD13Q42118139-AE09161C-5D3D-4EBC-A646-A0651DB3726AQ42460800-CA1B795E-5D26-4186-BBD0-AF76F79C9DE6Q44581657-29DAB016-6D09-4EE1-98D2-E407EA973C57Q50228181-18BAF6A5-A7E5-465B-A679-E206464302F5Q51054172-CFD7873D-9601-43BE-A217-DCA98466315F
P2860
Specific function of phosphoinositide 3-kinase beta in the control of DNA replication.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 22 April 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Specific function of phosphoinositide 3-kinase beta in the control of DNA replication.
@en
Specific function of phosphoinositide 3-kinase beta in the control of DNA replication.
@nl
type
label
Specific function of phosphoinositide 3-kinase beta in the control of DNA replication.
@en
Specific function of phosphoinositide 3-kinase beta in the control of DNA replication.
@nl
prefLabel
Specific function of phosphoinositide 3-kinase beta in the control of DNA replication.
@en
Specific function of phosphoinositide 3-kinase beta in the control of DNA replication.
@nl
P2860
P50
P356
P1476
Specific function of phosphoinositide 3-kinase beta in the control of DNA replication.
@en
P2093
Carmen Hernández
Susana Zuluaga
P2860
P304
P356
10.1073/PNAS.0812000106
P407
P577
2009-04-22T00:00:00Z