Inhibiting retinoic acid signaling ameliorates graft-versus-host disease by modifying T-cell differentiation and intestinal migration.
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Leukocyte homing, fate, and function are controlled by retinoic acidAcute graft-versus-host disease: a bench-to-bedside update.T cell progenitor therapy-facilitated thymopoiesis depends upon thymic input and continued thymic microenvironment interaction.Depletion of host CCR7(+) dendritic cells prevented donor T cell tissue tropism in anti-CD3-conditioned recipients.In vivo kinetics and nonradioactive imaging of rapidly proliferating cells in graft-versus-host diseaseRetinoic acid is essential for Th1 cell lineage stability and prevents transition to a Th17 cell program.Advances in understanding the pathogenesis of graft-versus-host disease.Pathogenesis of acute graft-versus-host disease: from intestinal microbiota alterations to donor T cell activation.Transcriptome analysis of GVHD reveals aurora kinase A as a targetable pathway for disease prevention.Retinoic acid controls the homeostasis of pre-cDC-derived splenic and intestinal dendritic cellsCD161+ Tconv and CD161+ Treg Share a Transcriptional and Functional Phenotype despite Limited Overlap in TCRβ RepertoireAltered homeostatic regulation of innate and adaptive immunity in lower gastrointestinal tract GVHD pathogenesis.Lower levels of vitamin A are associated with increased gastrointestinal graft-versus-host disease in children.Single and combined effect of retinoic acid and rapamycin modulate the generation, activity and homing potential of induced human regulatory T cells.A retinoic acid-dependent stroma-leukemia crosstalk promotes chronic lymphocytic leukemia progression.The vimentin intermediate filament network restrains regulatory T cell suppression of graft-versus-host disease
P2860
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P2860
Inhibiting retinoic acid signaling ameliorates graft-versus-host disease by modifying T-cell differentiation and intestinal migration.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 27 June 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Inhibiting retinoic acid signa ...... tion and intestinal migration.
@en
Inhibiting retinoic acid signa ...... tion and intestinal migration.
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type
label
Inhibiting retinoic acid signa ...... tion and intestinal migration.
@en
Inhibiting retinoic acid signa ...... tion and intestinal migration.
@nl
prefLabel
Inhibiting retinoic acid signa ...... tion and intestinal migration.
@en
Inhibiting retinoic acid signa ...... tion and intestinal migration.
@nl
P2093
P2860
P50
P1433
P1476
Inhibiting retinoic acid signa ...... tion and intestinal migration.
@en
P2093
David H Munn
Ethan Dmitrovsky
Kazutoshi Aoyama
Leshara M Fulton
Megan J Riddle
Patricia A Taylor
Rachelle G Veenstra
Randolph J Noelle
Roshantha A Chandraratna
P2860
P304
P356
10.1182/BLOOD-2012-11-470252
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P50
P577
2013-06-27T00:00:00Z