Junctophilin-2 is necessary for T-tubule maturation during mouse heart development.
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The junctophilin family of proteins: from bench to bedsideSildenafil ameliorates left ventricular T-tubule remodeling in a pressure overload-induced murine heart failure modelAnalysis of tubular membrane networks in cardiac myocytes from atria and ventricles.Irx4 identifies a chamber-specific cell population that contributes to ventricular myocardium development.Expression and function of Kv1.1 potassium channels in human atria from patients with atrial fibrillation.Alternative splicing regulates vesicular trafficking genes in cardiomyocytes during postnatal heart development.Regulation of Cardiomyocyte T-Tubular Structure: Opportunities for Therapy.Microdomain-specific localization of functional ion channels in cardiomyocytes: an emerging concept of local regulation and remodelling.AutoTT: automated detection and analysis of T-tubule architecture in cardiomyocytesCa(2+) homeostasis in sealed t-tubules of mouse ventricular myocytes.Impaired local regulation of ryanodine receptor type 2 by protein phosphatase 1 promotes atrial fibrillation.Reduced junctional Na+/Ca2+-exchanger activity contributes to sarcoplasmic reticulum Ca2+ leak in junctophilin-2-deficient mice.Dependence of cardiac transverse tubules on the BAR domain protein amphiphysin II (BIN-1)Identification of microRNA-mRNA dysregulations in paroxysmal atrial fibrillation.Physiologic force-frequency response in engineered heart muscle by electromechanical stimulation.Critical roles of junctophilin-2 in T-tubule and excitation-contraction coupling maturation during postnatal developmentCa²⁺ microdomains organized by junctophilinsEmerging roles of junctophilin-2 in the heart and implications for cardiac diseases.Calcium signalling in developing cardiomyocytes: implications for model systems and disease.MG53 is dispensable for T-tubule maturation but critical for maintaining T-tubule integrity following cardiac stress.Chronic heart failure: Ca(2+), catabolism, and catastrophic cell death.Cardiac Regeneration: Lessons From Development.Cardiac BIN1 (cBIN1) is a regulator of cardiac contractile function and an emerging biomarker of heart muscle health.Analysis of Cardiac Myocyte Maturation Using CASAAV, a Platform for Rapid Dissection of Cardiac Myocyte Gene Function In Vivo.Remodeling of the transverse tubular system after myocardial infarction in rabbit correlates with local fibrosis: A potential role of biomechanics.Junctophilin-2 gene therapy rescues heart failure by normalizing RyR2-mediated Ca2+ release.Junctophilin-2 at the intersection of arrhythmia and pathologic cardiac remodelingAlternative Splicing of Four Trafficking Genes Regulates Myofiber Structure and Skeletal Muscle PhysiologyThe Drosophila junctophilin gene is functionally equivalent to its four mammalian counterparts and is a modifier of a Huntingtin poly-Q expansion and the Notch pathway.Junctophilin-2 in the nanoscale organisation and functional signalling of ryanodine receptor clusters in cardiomyocytes.SPEG (Striated Muscle Preferentially Expressed Protein Kinase) Is Essential for Cardiac Function by Regulating Junctional Membrane Complex Activity.Cardiopatch platform enables maturation and scale-up of human pluripotent stem cell-derived engineered heart tissues.Heterogeneity of transverse-axial tubule system in mouse atria: Remodeling in atrial-specific Na+-Ca2+ exchanger knockout mice.Age- and strain-related aberrant Ca2+ release is associated with sudden cardiac death in the ACTC E99K mouse model of hypertrophic cardiomyopathy.Induced NCX1 overexpression attenuates pressure overload-induced pathological cardiac remodelling.Caveolin 3-dependent loss of t-tubular ICa during hypertrophy and heart failure in mice.Unraveling the Mechanisms by Which Calpain Inhibition Prevents Heart Failure Development
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Junctophilin-2 is necessary for T-tubule maturation during mouse heart development.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 27 May 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Junctophilin-2 is necessary for T-tubule maturation during mouse heart development.
@en
Junctophilin-2 is necessary for T-tubule maturation during mouse heart development.
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type
label
Junctophilin-2 is necessary for T-tubule maturation during mouse heart development.
@en
Junctophilin-2 is necessary for T-tubule maturation during mouse heart development.
@nl
prefLabel
Junctophilin-2 is necessary for T-tubule maturation during mouse heart development.
@en
Junctophilin-2 is necessary for T-tubule maturation during mouse heart development.
@nl
P2093
P2860
P50
P356
P1476
Junctophilin-2 is necessary for T-tubule maturation during mouse heart development
@en
P2093
Darlene G Skapura
David L Beavers
Julia O Reynolds
Michael J Ackerman
Sayali S Dixit
P2860
P356
10.1093/CVR/CVT133
P577
2013-05-27T00:00:00Z