Antagonism of the testis- and ovary-determining pathways during ovotestis development in mice. - Wikidata - awgldk - TriplyDB

Antagonism of the testis- and ovary-determining pathways during ovotestis development in mice.

Antagonism of the testis- and ovary-determining pathways during ovotestis development in mice.

http://www.wikidata.org/entity/Q37187812

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Building the mammalian testis: origins, differentiation, and assembly of the component cell populations Male sex determination: insights into molecular mechanisms Cell fate commitment during mammalian sex determination Antagonistic regulation of Cyp26b1 by transcription factors SOX9/SF1 and FOXL2 during gonadal development in mice NR5A1 is a novel disease gene for 46,XX testicular and ovotesticular disorders of sex development Transgenic expression of Map3k4 rescues T-associated sex reversal (Tas) in mice.Switching on sex: transcriptional regulation of the testis-determining gene Sry A novel mouse Fgfr2 mutant, hobbyhorse (hob), exhibits complete XY gonadal sex reversal.Minor abnormalities of testis development in mice lacking the gene encoding the MAPK signalling component, MAP3K1.Regulation of sex determination in mice by a non-coding genomic region.Determination and stability of gonadal sex Regulation of male sex determination: genital ridge formation and Sry activation in mice.Hematopoietic-Prostaglandin D2 synthase through PGD2 production is involved in the adult ovarian physiology.FOXL2 and BMP2 act cooperatively to regulate follistatin gene expression during ovarian development.Temporal differences in granulosa cell specification in the ovary reflect distinct follicle fates in mice.Normal Levels of Sox9 Expression in the Developing Mouse Testis Depend on the TES/TESCO Enhancer, but This Does Not Act Alone.The molecular and cellular basis of gonadal sex reversal in mice and humans.The forkhead transcription factor FOXL2 is expressed in somatic cells of the human ovary prior to follicle formation.Elucidation of the transcription network governing mammalian sex determination by exploiting strain-specific susceptibility to sex reversal.Sex and the circuitry: progress toward a systems-level understanding of vertebrate sex determination.FOXL2 transcriptionally represses Sf1 expression by antagonizing WT1 during ovarian development in mice.Gonadal development and tumor formation at the crossroads of male and female sex determination.Natural exceptions to normal gonad development in mammals.Genetic control of ovarian development.Early gonadogenesis in mammals: significance of long and narrow gonadal structure.FOXL2 and SOX9 distinguish the lineage of the sex cord-stromal cells in gonadoblastomas.Understanding sex determination in the mouse: genetics, epigenetics and the story of mutual antagonisms.The Gonadal Supporting Cell Lineage and Mammalian Sex Determination: The Differentiation of Sertoli and Granulosa Cells.Methods for the Study of Gonadal Development.Genetic Analyses Reveal Functions for MAP2K3 and MAP2K6 in Mouse Testis Determination.Human Sex Determination at the Edge of Ambiguity: INHERITED XY SEX REVERSAL DUE TO ENHANCED UBIQUITINATION AND PROTEASOMAL DEGRADATION OF A MASTER TRANSCRIPTION FACTOR.Loss of p300 and CBP disrupts histone acetylation at the mouse Sry promoter and causes XY gonadal sex reversal.Testis Determination Requires a Specific FGFR2 Isoform to Repress FOXL2.Different levels of testicular organization during gonadal differentiation in B6.Y(Tir) mice manifesting sex reversal.Identification of novel candidate genes for 46,XY disorders of sex development (DSD) using a C57BL/6J-Y POS mouse model.Analysis of gene function in cultured embryonic mouse gonads using nucleofection.Sox10 gain-of-function causes XX sex reversal in mice: implications for human 22q-linked disorders of sex development.Dynamic expression patterns of Irx3 and Irx5 during germline nest breakdown and primordial follicle formation promote follicle survival in mouse ovaries

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Antagonism of the testis- and ovary-determining pathways during ovotestis development in mice.

http://www.wikidata.org/entity/Q37187812

description

article científic

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article scientifique

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articolo scientifico

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bilimsel makale

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scientific article published on 06 March 2009

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Antagonism of the testis- and ...... ovotestis development in mice.

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Antagonism of the testis- and ...... ovotestis development in mice.

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Antagonism of the testis- and ...... ovotestis development in mice.

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Antagonism of the testis- and ...... ovotestis development in mice.

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Antagonism of the testis- and ...... ovotestis development in mice.

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Antagonism of the testis- and ...... ovotestis development in mice.

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J.MOD.2009.02.006

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Mechanisms of Development

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Antagonism of the testis- and ...... ovotestis development in mice.

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Eva M Eicher

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Linda L Washburn

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Marc Fellous

http://www.w3.org/2001/XMLSchema#string

Vy Truong

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P2860

Fgf9 and Wnt4 act as antagonistic signals to regulate mammalian sex determination

Up-regulation of WNT-4 signaling and dosage-sensitive sex reversal in humans.

Evolution and expression of FOXL2

Direct interaction of SRY-related protein SOX9 and steroidogenic factor 1 regulates transcription of the human anti-Müllerian hormone gene

The human testis determining factor SRY binds a nuclear factor containing PDZ protein interaction domains

Pairing SOX off: with partners in the regulation of embryonic development

Matching SOX: partner proteins and co-factors of the SOX family of transcriptional regulators

A dosage sensitive locus at chromosome Xp21 is involved in male to female sex reversal

Campomelic dysplasia and autosomal sex reversal caused by mutations in an SRY-related gene

Autosomal sex reversal and campomelic dysplasia are caused by mutations in and around the SRY-related gene SOX9

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324-336

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10.1016/J.MOD.2009.02.006

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