Separate domains of Rev1 mediate two modes of DNA damage bypass in mammalian cells. - Wikidata - awgldk - TriplyDB

Separate domains of Rev1 mediate two modes of DNA damage bypass in mammalian cells.

Separate domains of Rev1 mediate two modes of DNA damage bypass in mammalian cells.

http://www.wikidata.org/entity/Q37192014

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Separate roles of structured and unstructured regions of Y-family DNA polymerases Replication of Structured DNA and its implication in epigenetic stability The mechanisms of UV mutagenesis.REV1 and polymerase ζ facilitate homologous recombination repair Persistently stalled replication forks inhibit nucleotide excision repair in trans by sequestering Replication protein A.DNA-dependent protease activity of human Spartan facilitates replication of DNA-protein crosslink-containing DNA.Error-prone translesion replication of damaged DNA suppresses skin carcinogenesis by controlling inflammatory hyperplasia Kinetic basis of nucleotide selection employed by a protein template-dependent DNA polymerase PCNA ubiquitination is important, but not essential for translesion DNA synthesis in mammalian cells.Redundancy of mammalian Y family DNA polymerases in cellular responses to genomic DNA lesions induced by ultraviolet light Analysis of CPD ultraviolet lesion bypass in chicken DT40 cells: polymerase η and PCNA ubiquitylation play identical roles Proteasomal regulation of the mutagenic translesion DNA polymerase, Saccharomyces cerevisiae Rev1.Single cell analysis of human RAD18-dependent DNA post-replication repair by alkaline bromodeoxyuridine comet assay.Molecular chaperone Hsp90 regulates REV1-mediated mutagenesis.Excision of translesion synthesis errors orchestrates responses to helix-distorting DNA lesions.DNA damage bypass operates in the S and G2 phases of the cell cycle and exhibits differential mutagenicity.FANCD2 and REV1 cooperate in the protection of nascent DNA strands in response to replication stress.Replication Protein A Prohibits Diffusion of the PCNA Sliding Clamp along Single-Stranded DNA.Rev1 promotes replication through UV lesions in conjunction with DNA polymerases η, ι, and κ but not DNA polymerase ζ UV-triggered p21 degradation facilitates damaged-DNA replication and preserves genomic stability DNA polymerases and cancer.Replicating damaged DNA in eukaryotes.PPL2 translesion polymerase is essential for the completion of chromosomal DNA replication in the African trypanosome.Timing and spacing of ubiquitin-dependent DNA damage bypass.Propagation of histone marks and epigenetic memory during normal and interrupted DNA replication.Replication fork dynamics and the DNA damage response.REV1 and DNA polymerase zeta in DNA interstrand crosslink repair.The roles of DNA polymerase ζ and the Y family DNA polymerases in promoting or preventing genome instability.Translesion DNA synthesis and mutagenesis in eukaryotes DNA repair and cell cycle checkpoint defects as drivers and therapeutic targets in melanoma.Translesion synthesis mechanisms depend on the nature of DNA damage in UV-irradiated human cells.UV stalled replication forks restart by re-priming in human fibroblasts.Genomic and functional integrity of the hematopoietic system requires tolerance of oxidative DNA lesions.Identification of Small Molecule Translesion Synthesis Inhibitors That Target the Rev1-CT/RIR Protein-Protein Interaction.USP7 is essential for maintaining Rad18 stability and DNA damage tolerance.Histone H3.3 is required to maintain replication fork progression after UV damage.Determinants of G quadruplex-induced epigenetic instability in REV1-deficient cells.Mechanisms of DNA damage, repair, and mutagenesis.Eukaryotic Translesion DNA Synthesis on the Leading and Lagging Strands: Unique Detours around the Same Obstacle Different sets of translesion synthesis DNA polymerases protect from genome instability induced by distinct food-derived genotoxins.

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Separate domains of Rev1 mediate two modes of DNA damage bypass in mammalian cells.

http://www.wikidata.org/entity/Q37192014

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 30 March 2009

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Separate domains of Rev1 mediate two modes of DNA damage bypass in mammalian cells.

@en

Separate domains of Rev1 mediate two modes of DNA damage bypass in mammalian cells.

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type

label

Separate domains of Rev1 mediate two modes of DNA damage bypass in mammalian cells.

@en

Separate domains of Rev1 mediate two modes of DNA damage bypass in mammalian cells.

@nl

prefLabel

Separate domains of Rev1 mediate two modes of DNA damage bypass in mammalian cells.

@en

Separate domains of Rev1 mediate two modes of DNA damage bypass in mammalian cells.

@nl

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Molecular and Cellular Biology

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Separate domains of Rev1 mediate two modes of DNA damage bypass in mammalian cells.

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Anastasia Tsaalbi-Shtylik

http://www.w3.org/2001/XMLSchema#string

Ayal Hendel

http://www.w3.org/2001/XMLSchema#string

Fredrik Johansson

http://www.w3.org/2001/XMLSchema#string

Giel Hendriks

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Himabindu Gali

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Jacob G Jansen

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Klaus Erixon

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Lajos Haracska

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Leon H F Mullenders

http://www.w3.org/2001/XMLSchema#string

Niels de Wind

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The BRCT domain is a phospho-protein binding domain

Human SHPRH is a ubiquitin ligase for Mms2-Ubc13-dependent polyubiquitylation of proliferating cell nuclear antigen

Mouse Rev1 protein interacts with multiple DNA polymerases involved in translesion DNA synthesis

Polyubiquitination of proliferating cell nuclear antigen by HLTF and SHPRH prevents genomic instability from stalled replication forks

Human HLTF functions as a ubiquitin ligase for proliferating cell nuclear antigen polyubiquitination

The BRCT domain of mammalian Rev1 is involved in regulating DNA translesion synthesis

Vertebrate DNA damage tolerance requires the C-terminus but not BRCT or transferase domains of REV1

Deoxycytidyl transferase activity of yeast REV1 protein.

The 9-1-1 checkpoint clamp physically interacts with polzeta and is partially required for spontaneous polzeta-dependent mutagenesis in Saccharomyces cerevisiae.

A ubiquitin-binding motif in the translesion DNA polymerase Rev1 mediates its essential functional interaction with ubiquitinated proliferating cell nuclear antigen in response to DNA damage.

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3113-3123

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scholarly article

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10.1128/MCB.00071-09

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11

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29

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2009-03-30T00:00:00Z

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19332561

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2682010

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