Structural modulation of oxidative metabolism in design of improved benzothiophene selective estrogen receptor modulators.
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Diverse methyl sulfone-containing benzo[b]thiophene library via iodocyclization and palladium-catalyzed coupling.Selective estrogen receptor modulator delivery of quinone warheads to DNA triggering apoptosis in breast cancer cells.Novel selective estrogen mimics for the treatment of tamoxifen-resistant breast cancer.Benzothiophene Selective Estrogen Receptor Modulators Provide Neuroprotection by a novel GPR30-dependent MechanismThe naphthol selective estrogen receptor modulator (SERM), LY2066948, is oxidized to an o-quinone analogous to the naphthol equine estrogen, equilenin.Selective estrogen receptor modulator (SERM) lasofoxifene forms reactive quinones similar to estradiolSelective Human Estrogen Receptor Partial Agonists (ShERPAs) for Tamoxifen-Resistant Breast CancerNovel Selective Estrogen Receptor Downregulators (SERDs) Developed against Treatment-Resistant Breast Cancer.Benzothiophene carboxamide derivatives as inhibitors of Plasmodium falciparum enoyl-ACP reductase.
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P2860
Structural modulation of oxidative metabolism in design of improved benzothiophene selective estrogen receptor modulators.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 20 October 2008
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Structural modulation of oxida ...... estrogen receptor modulators.
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Structural modulation of oxida ...... estrogen receptor modulators.
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type
label
Structural modulation of oxida ...... estrogen receptor modulators.
@en
Structural modulation of oxida ...... estrogen receptor modulators.
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prefLabel
Structural modulation of oxida ...... estrogen receptor modulators.
@en
Structural modulation of oxida ...... estrogen receptor modulators.
@nl
P2093
P2860
P356
P1476
Structural modulation of oxida ...... estrogen receptor modulators.
@en
P2093
Cassia R Overk
Daniel D Lantvit
Gregory R J Thatcher
Irida Kastrati
Judy L Bolton
Rezene T Ashgodom
Richard B van Breemen
Yongsoo Choi
Zhihui Qin
P2860
P304
P356
10.1124/DMD.108.023408
P577
2008-10-20T00:00:00Z