High-throughput profiling of off-target DNA cleavage reveals RNA-programmed Cas9 nuclease specificity
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Concerning RNA-guided gene drives for the alteration of wild populationsCCTop: An Intuitive, Flexible and Reliable CRISPR/Cas9 Target Prediction ToolPlant genome editing made easy: targeted mutagenesis in model and crop plants using the CRISPR/Cas systemCRISPR/Cas9-mediated gene editing in human tripronuclear zygotesCas9 as a versatile tool for engineering biologyMulti-OMICs and Genome Editing Perspectives on Liver Cancer Signaling NetworksRecent Advances in Genome Editing Using CRISPR/Cas9Genome Engineering with TALE and CRISPR Systems in NeuroscienceThe Rise of CRISPR/Cas for Genome Editing in Stem CellsGenome-editing Technologies for Gene and Cell TherapyTargeting Non-Coding RNAs in Plants with the CRISPR-Cas Technology is a Challenge yet Worth AcceptingHow specific is CRISPR/Cas9 really?Origins of Programmable Nucleases for Genome EngineeringFrom Gene Targeting to Genome Editing: Transgenic animals applications and beyondGenome Editing Using Mammalian Haploid CellsEnabling functional genomics with genome engineeringCRISPR-Cas9: A Revolutionary Tool for Cancer ModellingDesigned nucleases for targeted genome editingOff-target Effects in CRISPR/Cas9-mediated Genome EngineeringA CRISPR method for genome engineeringMaking designer mutants in model organismsMeasuring and Reducing Off-Target Activities of Programmable Nucleases Including CRISPR-Cas9Quantifying on- and off-target genome editingRNA-guided CRISPR-Cas technologies for genome-scale investigation of disease processesCrystal Structure of Cas9 in Complex with Guide RNA and Target DNAThe epigenome: the next substrate for engineeringPatterns of CRISPR/Cas9 activity in plants, animals and microbesThe application of genome editing in studying hearing lossLiver-targeted gene therapy: Approaches and challengesTherapeutic genome editing: prospects and challengesDevelopment and applications of CRISPR-Cas9 for genome engineering.CRISPR/Cas9 allows efficient and complete knock-in of a destabilization domain-tagged essential protein in a human cell line, allowing rapid knockdown of protein functionIdentification of proteins associated with an IFNγ-responsive promoter by a retroviral expression system for enChIP using CRISPRCharacterizing Protease Specificity: How Many Substrates Do We Need?A Biophysical Model of CRISPR/Cas9 Activity for Rational Design of Genome Editing and Gene RegulationResources for functional genomics studies in Drosophila melanogasterCHOPCHOP v2: a web tool for the next generation of CRISPR genome engineeringFusion of catalytically inactive Cas9 to FokI nuclease improves the specificity of genome modificationCRISPR-Cas systems for editing, regulating and targeting genomesDouble nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificity
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High-throughput profiling of off-target DNA cleavage reveals RNA-programmed Cas9 nuclease specificity
description
article científic
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article scientifique
@fr
articolo scientifico
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artigo científico
@pt
bilimsel makale
@tr
scientific article published on 11 August 2013
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vedecký článok
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vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
High-throughput profiling of o ...... mmed Cas9 nuclease specificity
@en
High-throughput profiling of o ...... med Cas9 nuclease specificity.
@nl
type
label
High-throughput profiling of o ...... mmed Cas9 nuclease specificity
@en
High-throughput profiling of o ...... med Cas9 nuclease specificity.
@nl
prefLabel
High-throughput profiling of o ...... mmed Cas9 nuclease specificity
@en
High-throughput profiling of o ...... med Cas9 nuclease specificity.
@nl
P2093
P2860
P356
P1433
P1476
High-throughput profiling of o ...... mmed Cas9 nuclease specificity
@en
P2093
David R Liu
John P Guilinger
Steven Lin
Vikram Pattanayak
P2860
P2888
P304
P356
10.1038/NBT.2673
P577
2013-08-11T00:00:00Z
P5875
P6179
1007302590