The transcriptional coactivator MAML1 regulates p300 autoacetylation and HAT activity - Wikidata - awgldk - TriplyDB

The transcriptional coactivator MAML1 regulates p300 autoacetylation and HAT activity

The transcriptional coactivator MAML1 regulates p300 autoacetylation and HAT activity

http://www.wikidata.org/entity/Q37199554

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Protein lysine acetylation by p300/CBP Binding of the histone chaperone ASF1 to the CBP bromodomain promotes histone acetylation Krüppel-like factor 4 interacts with p300 to activate mitofusin 2 gene expression induced by all-trans retinoic acid in VSMCs Identification of C/EBPα as a novel target of the HPV8 E6 protein regulating miR-203 in human keratinocytes.Vascular histone deacetylation by pharmacological HDAC inhibition.Oncogenesis by sequestration of CBP/p300 in transcriptionally inactive hyperacetylated chromatin domains A novel Pzg-NURF complex regulates Notch target gene activity.Histone deacetylase inhibitors: the epigenetic therapeutics that repress hypoxia-inducible factors.SIRT1 regulates endothelial Notch signaling in lung cancer.MAML1 acts cooperatively with EGR1 to activate EGR1-regulated promoters: implications for nephrogenesis and the development of renal cancer.Amplified in breast cancer 1 promotes colorectal cancer progression through enhancing notch signaling.DDX5 is a positive regulator of oncogenic NOTCH1 signaling in T cell acute lymphoblastic leukemia Interaction with the DNA Repair Protein Thymine DNA Glycosylase Regulates Histone Acetylation by p300.The transcriptional coregulator MAML1 affects DNA methylation and gene expression patterns in human embryonic kidney cells.Improving understanding of chromatin regulatory proteins and potential implications for drug discovery.Allosteric regulation of epigenetic modifying enzymes.Arsenic alters global histone modifications in lymphocytes in vitro and in vivo.GSK3beta is a negative regulator of the transcriptional coactivator MAML1.Maml1 acts cooperatively with Gli proteins to regulate sonic hedgehog signaling pathway.Arsenic-induced suppression of kidney cell proliferation and the transcriptional coregulator MAML1.GCN5 acetylates and regulates the stability of the oncoprotein E2A-PBX1 in acute lymphoblastic leukemia.Systems approach to the pharmacological actions of HDAC inhibitors reveals EP300 activities and convergent mechanisms of regulation in diabetes.

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The transcriptional coactivator MAML1 regulates p300 autoacetylation and HAT activity

http://www.wikidata.org/entity/Q37199554

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 20 March 2009

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

The transcriptional coactivator MAML1 regulates p300 autoacetylation and HAT activity

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The transcriptional coactivator MAML1 regulates p300 autoacetylation and HAT activity.

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type

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The transcriptional coactivator MAML1 regulates p300 autoacetylation and HAT activity

@en

The transcriptional coactivator MAML1 regulates p300 autoacetylation and HAT activity.

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prefLabel

The transcriptional coactivator MAML1 regulates p300 autoacetylation and HAT activity

@en

The transcriptional coactivator MAML1 regulates p300 autoacetylation and HAT activity.

@nl

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Nucleic Acids Research

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The transcriptional coactivator MAML1 regulates p300 autoacetylation and HAT activity

@en

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Anita E Popko-Scibor

http://www.w3.org/2001/XMLSchema#string

Annika E Wallberg

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Beverley M Dancy

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Magnus L Hansson

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Mariana Saint Just Ribeiro

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Mikael J Lindberg

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Philip A Cole

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P2860

MAML1, a human homologue of Drosophila mastermind, is a transcriptional co-activator for NOTCH receptors

The notch regulator MAML1 interacts with p53 and functions as a coactivator

Coordination of p300-mediated chromatin remodeling and TRAP/mediator function through coactivator PGC-1alpha

The Notch coactivator, MAML1, functions as a novel coactivator for MEF2C-mediated transcription and is required for normal myogenesis

Structural basis for cooperativity in recruitment of MAML coactivators to Notch transcription complexes

Identification of a family of mastermind-like transcriptional coactivators for mammalian notch receptors.

Mastermind recruits CycC:CDK8 to phosphorylate the Notch ICD and coordinate activation with turnover

TRAP/SMCC/mediator-dependent transcriptional activation from DNA and chromatin templates by orphan nuclear receptor hepatocyte nuclear factor 4.

p300 and PCAF act cooperatively to mediate transcriptional activation from chromatin templates by notch intracellular domains in vitro

p300 acts as a transcriptional coactivator for mammalian Notch-1

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2996-3006

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scholarly article

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10.1093/NAR/GKP163

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9

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37

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2009-03-20T00:00:00Z

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24218180

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19304754

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2685096

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