Strategic Combination of DNA-Damaging Agent and PARP Inhibitor Results in Enhanced Cytotoxicity

Strategic Combination of DNA-Damaging Agent and PARP Inhibitor Results in Enhanced Cytotoxicity

Item
http://www.wikidata.org/entity/Q37205681
Effect of adriamycin on BRCA1 and PARP-1 expression in MCF-7 breast cancer cells.Common cancer-associated imbalances in the DNA damage response confer sensitivity to single agent ATR inhibition.Cytotoxic effects of fascaplysin against small cell lung cancer cell lines.Cisplatin resistance in germ cell tumours: models and mechanisms.Design, Synthesis, and Biological Evaluation of Novel PARP-1 Inhibitors Based on a 1H-Thieno[3,4-d] Imidazole-4-Carboxamide Scaffold.Osteosarcoma cells with genetic signatures of BRCAness are susceptible to the PARP inhibitor talazoparib alone or in combination with chemotherapeutics.Chromatin to Clinic: The Molecular Rationale for PARP1 Inhibitor Function.PARP inhibitors protect against sex- and AAG-dependent alkylation-induced neural degeneration.Population pharmacokinetics of ABT-767 in BRCA1 or BRCA2 mutation carriers with advanced solid tumors or in subjects with high grade serous ovarian, primary peritoneal or fallopian tube cancer.The search for a melanoma-tailored chemotherapy in the new era of personalized therapy: a phase II study of chemo-modulating temozolomide followed by fotemustine and a cooperative study of GOIM (Gruppo Oncologico Italia Meridionale).Corylin increases the sensitivity of hepatocellular carcinoma cells to chemotherapy through long noncoding RNA RAD51-AS1-mediated inhibition of DNA repair.
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Strategic Combination of DNA-Damaging Agent and PARP Inhibitor Results in Enhanced Cytotoxicity

Item
http://www.wikidata.org/entity/Q37205681
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 30 September 2013
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Strategic Combination of DNA-D ...... sults in Enhanced Cytotoxicity
@en
Strategic Combination of DNA-D ...... ults in Enhanced Cytotoxicity.
@nl
type
label
Strategic Combination of DNA-D ...... sults in Enhanced Cytotoxicity
@en
Strategic Combination of DNA-D ...... ults in Enhanced Cytotoxicity.
@nl
prefLabel
Strategic Combination of DNA-D ...... sults in Enhanced Cytotoxicity
@en
Strategic Combination of DNA-D ...... ults in Enhanced Cytotoxicity.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P478
P50
P577
P5875
P698
P921
P932
P356
P1433
P1476
Strategic Combination of DNA-D ...... sults in Enhanced Cytotoxicity
@en
P2093
P2860
P304
P31
P356
P478
P50
P577
P5875
P698
P921
P932