Sustained high-level polyclonal hematopoietic marking and transgene expression 4 years after autologous transplantation of rhesus macaques with SIV lentiviral vector-transduced CD34+ cells - Wikidata - awgldk - TriplyDB

Sustained high-level polyclonal hematopoietic marking and transgene expression 4 years after autologous transplantation of rhesus macaques with SIV lentiviral vector-transduced CD34+ cells

Sustained high-level polyclonal hematopoietic marking and transgene expression 4 years after autologous transplantation of rhesus macaques with SIV lentiviral vector-transduced CD34+ cells

http://www.wikidata.org/entity/Q37209028

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Hematopoietic stem cell gene therapy:assessing the relevance of preclinical models Hematopoietic stem cell engineering at a crossroads Accelerated lymphocyte reconstitution and long-term recovery after transplantation of lentiviral-transduced rhesus CD34+ cells mobilized by G-CSF and plerixafor Transduction of human primitive repopulating hematopoietic cells with lentiviral vectors pseudotyped with various envelope proteins.Future alternative therapies for β-thalassemia.Feline leukemia virus integrase and capsid packaging functions do not change the insertion profile of standard Moloney retroviral vectors Large animal models of hematopoietic stem cell gene therapy.Chicken HS4 insulators have minimal barrier function among progeny of human hematopoietic cells transduced with an HIV1-based lentiviral vector.Medicine. A comeback for gene therapy.In vitro functional correction of Hermansky-Pudlak Syndrome type-1 by lentiviral-mediated gene transfer.Gene therapy for canine leukocyte adhesion deficiency with lentiviral vectors using the murine stem cell virus and human phosphoglycerate kinase promoters.Contributions of gene marking to cell and gene therapies.No evidence for clonal selection due to lentiviral integration sites in human induced pluripotent stem cells.Differential Secondary Reconstitution of In Vivo-Selected Human SCID-Repopulating Cells in NOD/SCID versus NOD/SCID/γ chain Mice.Nonmyeloablative conditioning regimen to increase engraftment of gene-modified hematopoietic stem cells in young rhesus monkeys.Stem cell factor-displaying simian immunodeficiency viral vectors together with a low conditioning regimen allow for long-term engraftment of gene-marked autologous hematopoietic stem cells in macaques.High-efficiency transduction of rhesus hematopoietic repopulating cells by a modified HIV1-based lentiviral vector.Stem cell gene therapy: the risks of insertional mutagenesis and approaches to minimize genotoxicity.Transduction of human CD34+ repopulating cells with a self-inactivating lentiviral vector for SCID-X1 produced at clinical scale by a stable cell line.Amelioration of murine beta-thalassemia through drug selection of hematopoietic stem cells transduced with a lentiviral vector encoding both gamma-globin and the MGMT drug-resistance gene.In vivo selection of hematopoietic progenitor cells and temozolomide dose intensification in rhesus macaques through lentiviral transduction with a drug resistance gene.Ectopic platelet-delivered factor (F) VIII for the treatment of Hemophilia A: Plasma and platelet FVIII, is it all the same?No impact of lentiviral transduction on hematopoietic stem/progenitor cell telomere length or gene expression in the rhesus macaque model.Clonal tracking of rhesus macaque hematopoiesis highlights a distinct lineage origin for natural killer cells Gene therapy in thalassemia and hemoglobinopathies.Recent advances in gene therapy for thalassemia.RGB marking facilitates multicolor clonal cell tracking.Quantitative stability of hematopoietic stem and progenitor cell clonal output in rhesus macaques receiving transplants.The Ongoing Challenge of Hematopoietic Stem Cell-Based Gene Therapy for β-Thalassemia.Transgene expression in various organs post BM-HSC transplantation.Highly efficient stable expression of indoleamine 2,3 dioxygenase gene in primary fibroblasts.Blood's 70th anniversary: CARs on the Blood highway.Clonal dominance and transplantation dynamics in hematopoietic stem cell compartments.Stable long-term blood formation by stem cells in murine steady-state hematopoiesis.

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Sustained high-level polyclonal hematopoietic marking and transgene expression 4 years after autologous transplantation of rhesus macaques with SIV lentiviral vector-transduced CD34+ cells

http://www.wikidata.org/entity/Q37209028

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on April 2009

@en

vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

@cs

name

Sustained high-level polyclona ...... vector-transduced CD34+ cells

@en

Sustained high-level polyclona ...... vector-transduced CD34+ cells.

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type

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Sustained high-level polyclona ...... vector-transduced CD34+ cells

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Sustained high-level polyclona ...... vector-transduced CD34+ cells.

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Sustained high-level polyclona ...... vector-transduced CD34+ cells

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Sustained high-level polyclona ...... vector-transduced CD34+ cells.

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BLOOD-2008-10-185199

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Sustained high-level polyclona ...... vector-transduced CD34+ cells

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Andre Larochelle

http://www.w3.org/2001/XMLSchema#string

Arthur W Nienhuis

http://www.w3.org/2001/XMLSchema#string

Derek A Persons

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Gabriel Renaud

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Janice M Riberdy

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Jean Roayaei

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Keiko Akagi

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Peiman Hematti

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Rima Adler

http://www.w3.org/2001/XMLSchema#string

Robert E Donahue

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P2860

Evolutionary and Biomedical Insights from the Rhesus Macaque Genome

PACS-1 binding to adaptors is required for acidic cluster motif-mediated protein traffic.

Genome sequencing in microfabricated high-density picolitre reactors

Gene transfer in humans using a conditionally replicating lentiviral vector

Distinct genomic integration of MLV and SIV vectors in primate hematopoietic stem and progenitor cells

Retroviral DNA integration: ASLV, HIV, and MLV show distinct target site preferences

Functional analysis of human hematopoietic stem cell gene expression using zebrafish.

Gene therapy of human severe combined immunodeficiency (SCID)-X1 disease

LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1

Sustained correction of X-linked severe combined immunodeficiency by ex vivo gene therapy

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5434-5443

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scholarly article

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10.1182/BLOOD-2008-10-185199

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22

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113

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Cynthia E Dunbar

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2009-04-01T00:00:00Z

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24251379

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19339698

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2689045

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