Identification of Ikr kinetics and drug binding in native myocytes. - Wikidata - awgldk - TriplyDB

Identification of Ikr kinetics and drug binding in native myocytes.

Identification of Ikr kinetics and drug binding in native myocytes.

http://www.wikidata.org/entity/Q37213334

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Models of HERG gating Extracellular proton depression of peak and late Na⁺ current in the canine left ventricle.Cell-specific cardiac electrophysiology models.Developmental changes in expression and biophysics of ion channels in the canine ventricle.Allocryptopine and benzyltetrahydropalmatine block hERG potassium channels expressed in HEK293 cells Improving cardiomyocyte model fidelity and utility via dynamic electrophysiology protocols and optimization algorithms.Regulation of the voltage-insensitive step of HERG activation by extracellular pH.hERG inhibitors with similar potency but different binding kinetics do not pose the same proarrhythmic risk: implications for drug safety assessment.High-throughput screening of drug-binding dynamics to HERG improves early drug safety assessment.A Heart for Diversity: Simulating Variability in Cardiac Arrhythmia Research

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P2860

Identification of Ikr kinetics and drug binding in native myocytes.

http://www.wikidata.org/entity/Q37213334

description

article científic

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article scientifique

@fr

articolo scientifico

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artigo científico

@pt

bilimsel makale

@tr

scientific article published on 08 April 2009

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

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name

Identification of Ikr kinetics and drug binding in native myocytes.

@en

Identification of Ikr kinetics and drug binding in native myocytes.

@nl

type

label

Identification of Ikr kinetics and drug binding in native myocytes.

@en

Identification of Ikr kinetics and drug binding in native myocytes.

@nl

prefLabel

Identification of Ikr kinetics and drug binding in native myocytes.

@en

Identification of Ikr kinetics and drug binding in native myocytes.

@nl

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S10439-009-9690-5

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Annals of Biomedical Engineering

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Identification of Ikr kinetics and drug binding in native myocytes.

@en

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Andrew C Zygmunt

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Fernando Siso-Nadal

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Gregery T Buzzard

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Jonathan M Cordeiro

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Qinlian Zhou

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Robert E Miller

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P2860

A quantitative description of membrane current and its application to conduction and excitation in nerve

A mechanistic link between an inherited and an acquired cardiac arrhythmia: HERG encodes the IKr potassium channel

HERG, a human inward rectifier in the voltage-gated potassium channel family

Theory of the kinetic analysis of patch-clamp data

The role of stochastic and modal gating of cardiac L-type Ca2+ channels on early after-depolarizations

Activation and inactivation kinetics of an E-4031-sensitive current from single ferret atrial myocytes.

Model of intracellular calcium cycling in ventricular myocytes

A computational model of the human left-ventricular epicardial myocyte.

Maximum likelihood estimation of ion channel kinetics from macroscopic currents

The impact of drug-induced QT interval prolongation on drug discovery and development.

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1294-1309

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scholarly article

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10.1007/S10439-009-9690-5

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7

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37

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19353268

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