6-Hydroxy-1,2,4-triazine-3,5(2H,4H)-dione Derivatives as Novel D-Amino Acid Oxidase Inhibitors
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D-Amino acid oxidase inhibitors based on the 5-hydroxy-1,2,4-triazin-6(1H)-one scaffold.D-Amino-Acid Oxidase Inhibition Increases D-Serine Plasma Levels in Mouse But not in Monkey or Dog.Mouse d-Amino-Acid Oxidase: Distribution and Physiological Substrates.Oral administration of D-alanine in monkeys robustly increases plasma and cerebrospinal fluid levels but experimental D-amino acid oxidase inhibitors had minimal effect.Competitive Inhibitors Unveil Structure/Function Relationships in Human D-Amino Acid Oxidase.
P2860
6-Hydroxy-1,2,4-triazine-3,5(2H,4H)-dione Derivatives as Novel D-Amino Acid Oxidase Inhibitors
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 26 August 2015
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
6-Hydroxy-1,2,4-triazine-3,5(2 ...... -Amino Acid Oxidase Inhibitors
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6-Hydroxy-1,2,4-triazine-3,5(2 ...... Amino Acid Oxidase Inhibitors.
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type
label
6-Hydroxy-1,2,4-triazine-3,5(2 ...... -Amino Acid Oxidase Inhibitors
@en
6-Hydroxy-1,2,4-triazine-3,5(2 ...... Amino Acid Oxidase Inhibitors.
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prefLabel
6-Hydroxy-1,2,4-triazine-3,5(2 ...... -Amino Acid Oxidase Inhibitors
@en
6-Hydroxy-1,2,4-triazine-3,5(2 ...... Amino Acid Oxidase Inhibitors.
@nl
P2093
P2860
P1476
6-Hydroxy-1,2,4-triazine-3,5(2 ...... -Amino Acid Oxidase Inhibitors
@en
P2093
Ajit G Thomas
Barbara S Slusher
Bridget Duvall
Camilo Rojas
Krystyna M Wozniak
Niyada Hin
P2860
P304
P356
10.1021/ACS.JMEDCHEM.5B00482
P407
P577
2015-09-03T00:00:00Z