PTEN: a default gate-keeping tumor suppressor with a versatile tail.
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SCF(β-TRCP)-mediated degradation of NEDD4 inhibits tumorigenesis through modulating the PTEN/Akt signaling pathwayPTEN regulation of ERK1/2 signaling in cancerStructural mutation analysis of PTEN and its genotype-phenotype correlations in endometriosis and cancerPTEN attenuates PIP3/Akt signaling in the cochlea of the aging CBA/J mouse.Plk1 protein phosphorylates phosphatase and tensin homolog (PTEN) and regulates its mitotic activity during the cell cycleAssociation between PTEN Gene IVS4 polymorphism and risk of cancer: a meta-analysisCdh1, a substrate-recruiting component of anaphase-promoting complex/cyclosome (APC/C) ubiquitin E3 ligase, specifically interacts with phosphatase and tensin homolog (PTEN) and promotes its removal from chromatin.Key signalling nodes in mammary gland development and cancer. Signalling downstream of PI3 kinase in mammary epithelium: a play in 3 Akts.A novel human TPIP splice-variant (TPIP-C2) mRNA, expressed in human and mouse tissues, strongly inhibits cell growth in HeLa cells.PTEN as a prognostic and predictive marker in postoperative radiotherapy for squamous cell cancer of the head and neck.A new role for PTEN in regulating transient receptor potential canonical channel 6-mediated Ca2+ entry, endothelial permeability, and angiogenesis.Metastasis-associated protein 1/histone deacetylase 4-nucleosome remodeling and deacetylase complex regulates phosphatase and tensin homolog gene expression and function.Inhibition of phosphatase and tensin homolog deleted on chromosome 10 decreases rat cortical neuron injury and blood-brain barrier permeability, and improves neurological functional recovery in traumatic brain injury model.ROS enhances CXCR4-mediated functions through inactivation of PTEN in prostate cancer cells.ROS-mediated activation of AKT induces apoptosis via pVHL in prostate cancer cellsA novel PTEN gene promoter mutation and untypical Cowden syndrome.Molecular Features of Phosphatase and Tensin Homolog (PTEN) Regulation by C-terminal Phosphorylation.Curcumin cytotoxicity is enhanced by PTEN disruption in colorectal cancer cellsRegulation of the Tumor-Suppressor Function of the Class III Phosphatidylinositol 3-Kinase Complex by Ubiquitin and SUMONew Treatment Opportunities in Phosphatase and Tensin Homolog (PTEN)-Deficient Tumors: Focus on PTEN/Focal Adhesion Kinase Pathway.Phosphatase and tensin homolog (PTEN) expression on oncologic outcome in renal cell carcinoma: A systematic review and meta-analysis.Cell cycle arrest and apoptosis by expression of a novel TPIP (TPIP-C2) cDNA encoding a C2-domain in HEK-293 cells.Chromatin PTEN is involved in DNA damage response partly through regulating Rad52 sumoylation.Association of PTEN expression with biochemical recurrence in prostate cancer: results based on previous reports.SYNJ2BP promotes the degradation of PTEN through the lysosome-pathway and enhances breast tumor metastasis via PI3K/AKT/SNAI1 signaling.Estimate of the accelerated proliferation by protein tyrosine phosphatase (PTEN) over expression in postoperative radiotherapy of head and neck squamous cell carcinoma.The association of phosphatase and tensin homolog deleted on chromosome 10 polymorphisms and lifestyle habits with colorectal cancer risk in a Chinese population.
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PTEN: a default gate-keeping tumor suppressor with a versatile tail.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on August 2008
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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PTEN: a default gate-keeping tumor suppressor with a versatile tail.
@en
PTEN: a default gate-keeping tumor suppressor with a versatile tail.
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PTEN: a default gate-keeping tumor suppressor with a versatile tail.
@en
PTEN: a default gate-keeping tumor suppressor with a versatile tail.
@nl
prefLabel
PTEN: a default gate-keeping tumor suppressor with a versatile tail.
@en
PTEN: a default gate-keeping tumor suppressor with a versatile tail.
@nl
P2860
P356
P1433
P1476
PTEN: a default gate-keeping tumor suppressor with a versatile tail.
@en
P2093
Xinjiang Wang
Xuejun Jiang
P2860
P2888
P304
P356
10.1038/CR.2008.83
P577
2008-08-01T00:00:00Z
P5875
P6179
1023507396